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  1. Article ; Online: Assessment of pulmonary arterial circulation 3 months after hospitalization for SARS-CoV-2 pneumonia: Dual-energy CT (DECT) angiographic study in 55 patients.

    Remy-Jardin, Martine / Duthoit, Louise / Perez, Thierry / Felloni, Paul / Faivre, Jean-Baptiste / Fry, Stéphanie / Bautin, Nathalie / Chenivesse, Cécile / Remy, Jacques / Duhamel, Alain

    EClinicalMedicine

    2021  Volume 34, Page(s) 100778

    Abstract: ... 3 months after hospitalization for SARS-CoV-2 pneumonia in patients with persistent respiratory ... of pulmonology. Among them, dual-energy CT angiography (DECTA) was obtained in 55 patients.: Findings: The 55 ... symptoms.: Methods: Among the 320 patients who participated in a systematic follow-up 3 months after ...

    Abstract Background: During COVID-19, the main manifestations of the disease are not only pneumonia but also coagulation disorders. The purpose of this study was to evaluate pulmonary vascular abnormalities 3 months after hospitalization for SARS-CoV-2 pneumonia in patients with persistent respiratory symptoms.
    Methods: Among the 320 patients who participated in a systematic follow-up 3 months after hospitalization, 76 patients had residual symptoms justifying a specialized follow-up in the department of pulmonology. Among them, dual-energy CT angiography (DECTA) was obtained in 55 patients.
    Findings: The 55 patients had partial (
    Interpretation: DECT depicted proximal arterial thrombosis in 5.4% of patients and perfusion abnormalities suggestive of widespread microangiopathy in 65.5% of patients. Lung microcirculation was abnormal in 4 patients with normal lung parenchyma.
    Language English
    Publishing date 2021-03-30
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2021.100778
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Assessment of pulmonary arterial circulation 3 months after hospitalization for SARS-CoV-2 pneumonia

    Martine Remy-Jardin / Louise Duthoit / Thierry Perez / Paul Felloni / Jean-Baptiste Faivre / Stéphanie Fry / Nathalie Bautin / Cécile Chenivesse / Jacques Remy / Alain Duhamel

    EClinicalMedicine, Vol 34, Iss , Pp 100778- (2021)

    Dual-energy CT (DECT) angiographic study in 55 patients

    2021  

    Abstract: ... after hospitalization for SARS-CoV-2 pneumonia in patients with persistent respiratory symptoms. Methods ... Among them, dual-energy CT angiography (DECTA) was obtained in 55 patients. Findings: The 55 patients had partial ... Among the 320 patients who participated in a systematic follow-up 3 months after hospitalization, 76 patients ...

    Abstract Background: During COVID-19, the main manifestations of the disease are not only pneumonia but also coagulation disorders. The purpose of this study was to evaluate pulmonary vascular abnormalities 3 months after hospitalization for SARS-CoV-2 pneumonia in patients with persistent respiratory symptoms. Methods: Among the 320 patients who participated in a systematic follow-up 3 months after hospitalization, 76 patients had residual symptoms justifying a specialized follow-up in the department of pulmonology. Among them, dual-energy CT angiography (DECTA) was obtained in 55 patients. Findings: The 55 patients had partial (n = 40; 72.7%) or complete (n = 15; 27.3%) resolution of COVID-19 lung infiltration. DECTA was normal in 52 patients (52/55; 94.6%) and showed endoluminal filling defects in 3 patients (3/55; 5.4%) at the level of one (n = 1) and two (n = 1) segmental arteries of a single lobe and within central and peripheral arteries (n = 1). DECT lung perfusion was rated as non-interpretable (n = 2;3.6%), normal (n = 17; 30.9%) and abnormal (n = 36; 65.5%), the latter group comprising 32 patients with residual COVID-19 opacities (32/36; 89%) and 4 patients with normal lung parenchyma (4/36; 11%). Perfusion abnormalities consisted of (a) patchy defects (30/36; 83%), (b) PE-type defects (6/36; 16.6%) with (n = 1) or without proximal thrombosis (n = 5); and (c) focal areas of hypoperfusion (2/36; 5.5%). Increased perfusion was seen in 15 patients, always matching GGOs, bands and/or vascular tree-in- bud patterns. Interpretation: DECT depicted proximal arterial thrombosis in 5.4% of patients and perfusion abnormalities suggestive of widespread microangiopathy in 65.5% of patients. Lung microcirculation was abnormal in 4 patients with normal lung parenchyma.
    Keywords CT angiography ; Dual-energy CT ; Lung perfusion ; Pulmonary embolism ; COVID-19 ; Medicine (General) ; R5-920
    Subject code 610
    Language English
    Publishing date 2021-04-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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