Article: Endocarditis caused by Coccidioides species.
2004 Volume 79, Issue 11, Page(s) 1451–1454
Abstract: Endocarditis caused by Coccidioides species has been reported rarely. Herein, we report 2 ... from blood cultures. The patients had a wide range of serologic titers for Coccidioides species (1:1-1:2048 ... endocarditis is an uncommon manifestation of Coccidioides infection that connotes a poor prognosis. ...
| Abstract | Endocarditis caused by Coccidioides species has been reported rarely. Herein, we report 2 such cases and summarize 4 published reports. Coccidioidal endocarditis was found in patients who had prolonged or disseminated infection. Vegetations were identified on mitral or aortic valves or valvular rings, and embolic phenomena were observed. Diagnosis was hindered by uniformly negative results from blood cultures. The patients had a wide range of serologic titers for Coccidioides species (1:1-1:2048). The infection was fatal in 4 of the 6 patients whose cases we reviewed. We conclude that coccidioidal endocarditis is an uncommon manifestation of Coccidioides infection that connotes a poor prognosis. |
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| MeSH term(s) | Adult ; Antifungal Agents/therapeutic use ; Coccidioides/isolation & purification ; Coccidioidomycosis/complications ; Coccidioidomycosis/drug therapy ; Endocarditis/drug therapy ; Endocarditis/microbiology ; Fatal Outcome ; Humans ; Male ; Middle Aged |
| Chemical Substances | Antifungal Agents |
| Language | English |
| Publishing date | 2004-11 |
| Publishing country | England |
| Document type | Case Reports ; Journal Article ; Review |
| ZDB-ID | 124027-4 |
| ISSN | 1942-5546 ; 0025-6196 |
| ISSN (online) | 1942-5546 |
| ISSN | 0025-6196 |
| DOI | 10.4065/79.11.1451 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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