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Article ; Online: Past, present and future of spike sorting techniques.

Rey, Hernan Gonzalo / Pedreira, Carlos / Quian Quiroga, Rodrigo

Brain research bulletin

2015  Volume 119, Issue Pt B, Page(s) 106–117

Abstract: ... to support the neuroscientific research of the near future. ... Spike sorting is a crucial step to extract information from extracellular recordings. With new ... assess the performance of new algorithms. In this work, we review the basic concepts of spike sorting ...

Abstract Spike sorting is a crucial step to extract information from extracellular recordings. With new recording opportunities provided by the development of new electrodes that allow monitoring hundreds of neurons simultaneously, the scenario for the new generation of algorithms is both exciting and challenging. However, this will require a new approach to the problem and the development of a common reference framework to quickly assess the performance of new algorithms. In this work, we review the basic concepts of spike sorting, including the requirements for different applications, together with the problems faced by presently available algorithms. We conclude by proposing a roadmap stressing the crucial points to be addressed to support the neuroscientific research of the near future.
MeSH term(s) Action Potentials/physiology ; Algorithms ; Animals ; Computer Simulation ; Electrodes, Implanted ; Humans ; Models, Neurological ; Neuroimaging/instrumentation ; Neuroimaging/methods ; Neurons/physiology
Language English
Publishing date 2015-04-27
Publishing country United States
Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID 197620-5
ISSN 1873-2747 ; 0361-9230
ISSN (online) 1873-2747
ISSN 0361-9230
DOI 10.1016/j.brainresbull.2015.04.007
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