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  1. Article ; Online: Kinetics and seroprevalence of SARS-CoV-2 antibodies in children.

    Roarty, Cathal / Tonry, Claire / McFetridge, Lisa / Mitchell, Hannah / Watson, Chris / Waterfield, Thomas

    The Lancet. Infectious diseases

    2020  Volume 21, Issue 6, Page(s) e143

    MeSH term(s) Adolescent ; Antibodies, Viral/immunology ; COVID-19/epidemiology ; COVID-19/immunology ; Child ; Child, Preschool ; Humans ; Immunoglobulin G/blood ; Kinetics ; SARS-CoV-2/immunology ; Seroepidemiologic Studies ; United Kingdom/epidemiology
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2020-11-19
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 2061641-7
    ISSN 1474-4457 ; 1473-3099
    ISSN (online) 1474-4457
    ISSN 1473-3099
    DOI 10.1016/S1473-3099(20)30884-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Seroprevalence kinetics of SARS-CoV-2 antibodies in pediatric patients visiting a hospital during COVID-19 pandemic in Japan.

    Hashimoto, Takehiro / Yahiro, Takaaki / Khan, Sakirul / Kimitsuki, Kazunori / Suzuki, Masayoshi / Fujimoto, Tamotsu / Tanaka, Toshihiro / Saito, Nobuo / Hiramatsu, Kazufumi / Nishizono, Akira

    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy

    2023  Volume 30, Issue 2, Page(s) 169–171

    Abstract: ... on the seroprevalence kinetics of SARS-CoV-2 antibodies in children are limited. We conducted a cross-sectional survey ... Children infected with SARS-CoV-2 are often asymptomatic or have mild symptoms. The studies ... in children <1 year of age, the prevalence was 4.0%, and 2.4%, 5.3%, 5.2% and 10% in age groups 1-4, 5-9, 10 ...

    Abstract Children infected with SARS-CoV-2 are often asymptomatic or have mild symptoms. The studies on the seroprevalence kinetics of SARS-CoV-2 antibodies in children are limited. We conducted a cross-sectional survey of the positive rate of the SARS-CoV-2 IgG in pediatric patients without suspected COVID-19 infection between January 2007 and March 2022. We defined the serum samples from the pre-pandemic and pandemic groups (1st-6th waves). Totally, 2557 samples were collected and no samples from the pre-pandemic group or the 1st-4th waves were positive for IgG. There were 4/661 and 16/373 positives at the 5th and 6th waves, respectively. At the 5th wave, the prevalence of IgG was 1.3% in children aged 1-4 years. At the 6th wave, in children <1 year of age, the prevalence was 4.0%, and 2.4%, 5.3%, 5.2% and 10% in age groups 1-4, 5-9, 10-14 and 15-18 years, respectively. In conclusions, the pre-pandemic samples were negative, and the IgG positivity increased during the later period of the pandemic.
    MeSH term(s) Humans ; Child ; Infant ; COVID-19/epidemiology ; SARS-CoV-2 ; Japan/epidemiology ; Pandemics ; Cross-Sectional Studies ; Seroepidemiologic Studies ; Hospitals ; Antibodies, Viral ; Immunoglobulin G
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2023-09-19
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1355399-9
    ISSN 1437-7780 ; 1341-321X
    ISSN (online) 1437-7780
    ISSN 1341-321X
    DOI 10.1016/j.jiac.2023.09.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Kinetics and seroprevalence of SARS-CoV-2 antibodies: a comparison of 3 different assays.

    Kahre, Elisabeth / Galow, Lukas / Unrath, Manja / Haag, Luise / Blankenburg, Judith / Dalpke, Alexander H / Lück, Christian / Berner, Reinhard / Armann, Jakob P

    Scientific reports

    2021  Volume 11, Issue 1, Page(s) 14893

    Abstract: ... in seropositivity in the Euroimmun and Abbott assays. There are significant differences in SARS-CoV-2 antibody ... for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection ... Comparing seroprevalence and antibody kinetics in three different commercially available assays ...

    Abstract Comparing seroprevalence and antibody kinetics in three different commercially available assays for SARS-CoV-2. Serostatus of COVID-19 patients was analyzed 5 months and 10 months after their infection, using three different assays: Diasorin LIAISON, Euroimmun, Abbott Diagnostics ARCHITECT. Seropositivity at baseline differed significantly depending on the assay (Diasorin 81%, Euroimmun 83%, Abbott 59%). At follow-up antibody levels detected in the Diasorin assay were stable, while there was a significant loss in seropositivity in the Euroimmun and Abbott assays. There are significant differences in SARS-CoV-2 antibody kinetics based on the specific assay used.
    MeSH term(s) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Antibodies, Viral/analysis ; Antibodies, Viral/immunology ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/virology ; COVID-19 Testing/methods ; Child ; Child, Preschool ; Female ; Germany/epidemiology ; Humans ; Immunoglobulin G/analysis ; Immunoglobulin G/immunology ; Male ; Middle Aged ; SARS-CoV-2/immunology ; Sensitivity and Specificity ; Seroepidemiologic Studies
    Chemical Substances Antibodies, Viral ; Immunoglobulin G
    Language English
    Publishing date 2021-07-21
    Publishing country England
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-021-94453-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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