Article: Acute kidney injury risk assessment at the hospital front door: what is the best measure of risk?
2015 Volume 8, Issue 6, Page(s) 673–680
Abstract: Background: We examined the prevalence of acute kidney injury (AKI) risk factors in the emergency ... medical unit, generated a modified risk assessment tool and tested its ability to predict AKI.: Methods ... associated AKI risk factors may not facilitate clinicians to apportion risk. This suggests that additional ...
| Abstract | Background: We examined the prevalence of acute kidney injury (AKI) risk factors in the emergency medical unit, generated a modified risk assessment tool and tested its ability to predict AKI. Methods: A total of 1196 patients admitted to medical admission units were assessed for patient-associated AKI risk factors. Subsequently, 898 patients were assessed for a limited number of fixed risk factors with the addition of hypotension and sepsis. This was correlated to AKI episodes. Results: In the first cohort, the prevalence of AKI risk factors was 2.1 ± 2.0 per patient, with a positive relationship between age and the number of risk factors and a higher number of risk factors in patients ≥65 years. In the second cohort, 12.3% presented with or developed AKI. Patients with AKI were older and had a higher number of AKI risk factors. In the AKI cohort, 72% of the patients had two or more AKI risk factors compared with 43% of the cohort with no AKI. When age ≥65 years was added as an independent risk factor, 84% of those with AKI had two or more AKI risk factors compared with 55% of those with no AKI. Receiver operating characteristic analysis suggests that the use of common patient-associated known AKI risk factors performs no better than age alone as a predictor of AKI. Conclusions: Detailed assessment of well-established patient-associated AKI risk factors may not facilitate clinicians to apportion risk. This suggests that additional work is required to develop a more sensitive validated AKI-predictive tool that would be useful in this clinical setting. |
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| Language | English | |||||
| Publishing date | 2015-08-30 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 2655800-2 | |||||
| ISSN | 2048-8513 ; 2048-8505 | |||||
| ISSN (online) | 2048-8513 | |||||
| ISSN | 2048-8505 | |||||
| DOI | 10.1093/ckj/sfv080 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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