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Article: Different effects of influenza virus, respiratory syncytial virus, and Sendai virus on human lymphocytes and macrophages.

Roberts, N J

Infection and immunity

1982  Volume 35, Issue 3, Page(s) 1142–1146

Abstract: Influenza virus, respiratory syncytial virus, and Sendai virus depress human cell-mediated immune ... of lymphocytes, or macrophages, or both cell types. ... other immune defense mechanisms, such as interferon production. Exposure to the different viruses resulted ...

Abstract Influenza virus, respiratory syncytial virus, and Sendai virus depress human cell-mediated immune responses, such as mitogen-induced lymphocyte transformation, but differ in their ability to induce other immune defense mechanisms, such as interferon production. Exposure to the different viruses resulted in depressed transformation responses to the mitogen phytohemagglutinin by affecting the function of lymphocytes, or macrophages, or both cell types.
MeSH term(s) Adult ; Female ; Humans ; Influenza A virus/physiology ; Interferons/biosynthesis ; Lymphocyte Activation ; Lymphocytes/immunology ; Macrophages/immunology ; Male ; Parainfluenza Virus 1, Human/physiology ; Phytohemagglutinins/pharmacology ; Respiratory Syncytial Viruses/physiology
Chemical Substances Phytohemagglutinins ; Interferons (9008-11-1)
Language English
Publishing date 1982-03
Publishing country United States
Document type Comparative Study ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID 218698-6
ISSN 1098-5522 ; 0019-9567
ISSN (online) 1098-5522
ISSN 0019-9567
DOI 10.1128/iai.35.3.1142-1146.1982
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