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  1. Article ; Online: Mass severe acute respiratory coronavirus 2 (SARS-CoV-2) testing of asymptomatic healthcare personnel - ERRATUM.

    Roberts, Scott C / Peaper, David R / Thorne, Craig D / Sussman, L Scott / Murray, Thomas S / Choi, Steven J / Pettker, Christian M / Russi, Mark B / Martinello, Richard A

    Infection control and hospital epidemiology

    2021  Volume 43, Issue 9, Page(s) 1312

    MeSH term(s) COVID-19/diagnosis ; COVID-19 Testing ; Delivery of Health Care ; Health Personnel ; Humans ; SARS-CoV-2
    Language English
    Publishing date 2021-03-29
    Publishing country United States
    Document type Journal Article ; Published Erratum
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.107
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Mass severe acute respiratory coronavirus 2 (SARS-CoV-2) testing of asymptomatic healthcare personnel.

    Roberts, Scott C / Peaper, David R / Thorne, Craig D / Sussman, L Scott / Murray, Thomas S / Choi, Steven J / Pettker, Christian M / Russi, Mark B / Martinello, Richard A

    Infection control and hospital epidemiology

    2021  Volume 42, Issue 5, Page(s) 625–626

    Abstract: Mass asymptomatic SARS-CoV-2 nucleic acid amplified testing of healthcare personnel (HCP) was ...

    Abstract Mass asymptomatic SARS-CoV-2 nucleic acid amplified testing of healthcare personnel (HCP) was performed at a large tertiary health system. A low period-prevalence of positive HCP was observed. Of those who tested positive, half had mild symptoms in retrospect. HCP with even mild symptoms should be isolated and tested.
    MeSH term(s) Asymptomatic Infections/epidemiology ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19 Testing/statistics & numerical data ; Connecticut/epidemiology ; Health Personnel/statistics & numerical data ; Humans ; SARS-CoV-2/isolation & purification
    Language English
    Publishing date 2021-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639378-0
    ISSN 1559-6834 ; 0195-9417 ; 0899-823X
    ISSN (online) 1559-6834
    ISSN 0195-9417 ; 0899-823X
    DOI 10.1017/ice.2021.9
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1714: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Excellent option for mass testing during the SARS-CoV-2 pandemic: painless self-collection and direct RT-qPCR.

    Kriegova, Eva / Fillerova, Regina / Raska, Milan / Manakova, Jirina / Dihel, Martin / Janca, Ondrej / Sauer, Pavel / Klimkova, Martina / Strakova, Petra / Kvapil, Petr

    Virology journal

    2021  Volume 18, Issue 1, Page(s) 95

    Abstract: ... for the sensitive PCR detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This approach was ... nasal-swab self-collection and direct RT-qPCR for mass testing during the SARS-CoV-2 pandemic and ... nasopharyngeal swabs obtained with the assistance of healthcare personnel and analysed by classic two-step RT ...

    Abstract The early identification of asymptomatic yet infectious cases is vital to curb the 2019 coronavirus (COVID-19) pandemic and to control the disease in the post-pandemic era. In this paper, we propose a fast, inexpensive and high-throughput approach using painless nasal-swab self-collection followed by direct RT-qPCR for the sensitive PCR detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This approach was validated in a large prospective cohort study of 1038 subjects, analysed simultaneously using (1) nasopharyngeal swabs obtained with the assistance of healthcare personnel and analysed by classic two-step RT-qPCR on RNA isolates and (2) nasal swabs obtained by self-collection and analysed with direct RT-qPCR. Of these subjects, 28.6% tested positive for SARS-CoV-2 using nasopharyngeal swab sampling. Our direct RT-qPCR approach for self-collected nasal swabs performed well with results similar to those of the two-step RT-qPCR on RNA isolates, achieving 0.99 positive and 0.98 negative predictive values (cycle threshold [Ct] < 37). Our research also reports on grey-zone viraemia, including samples with near-cut-off Ct values (Ct ≥ 37). In all investigated subjects (n = 20) with grey-zone viraemia, the ultra-small viral load disappeared within hours or days with no symptoms. Overall, this study underscores the importance of painless nasal-swab self-collection and direct RT-qPCR for mass testing during the SARS-CoV-2 pandemic and in the post-pandemic era.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/prevention & control ; COVID-19 Testing/methods ; Clinical Laboratory Techniques/methods ; Diagnostic Tests, Routine/methods ; Humans ; Mass Screening/methods ; Real-Time Polymerase Chain Reaction ; SARS-CoV-2/genetics ; Self-Examination/methods ; Sensitivity and Specificity ; Specimen Handling/methods ; Surveys and Questionnaires ; Viral Load/methods
    Language English
    Publishing date 2021-05-04
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
    ZDB-ID 2160640-7
    ISSN 1743-422X ; 1743-422X
    ISSN (online) 1743-422X
    ISSN 1743-422X
    DOI 10.1186/s12985-021-01567-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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