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  1. Article: Anterior instability of the shoulder after trauma.

    Robinson, C M / Dobson, R J

    The Journal of bone and joint surgery. British volume

    2004  Volume 86, Issue 4, Page(s) 469–479

    MeSH term(s) Athletic Injuries/complications ; Athletic Injuries/therapy ; Humans ; Joint Instability/etiology ; Joint Instability/surgery ; Recurrence ; Risk Factors ; Shoulder Dislocation/complications ; Shoulder Dislocation/therapy
    Language English
    Publishing date 2004-03-15
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 220626-2
    ISSN 2044-5377 ; 0301-620X ; 0447-9076
    ISSN (online) 2044-5377
    ISSN 0301-620X ; 0447-9076
    DOI 10.1302/0301-620x.86b4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The prevalence of shoulders with a large glenoid defect and small bone fragment increases after several instability events during conservative treatment for traumatic anterior instability.

    Nakagawa, Shigeto / Take, Yasuhiro / Mizuno, Naoko / Ozaki, Ritsuro / Hanai, Hiroto / Iuchi, Ryo / Kinugasa, Kazutaka

    JSES international

    2023  Volume 7, Issue 4, Page(s) 538–543

    Abstract: ... for traumatic anterior instability.: Methods: We retrospectively investigated 114 shoulders that underwent ... conservative treatment and computed tomography (CT) examination at least twice after an instability event ... fragment increases significantly after several instability events. ...

    Abstract Background: Unstable shoulders with a large glenoid defect and small bone fragment are at higher risk for postoperative recurrence after arthroscopic Bankart repair. The purpose of the present study was to clarify the changes in the prevalence of such shoulders during conservative treatment for traumatic anterior instability.
    Methods: We retrospectively investigated 114 shoulders that underwent conservative treatment and computed tomography (CT) examination at least twice after an instability event in the period from July 2004 to December 2021. We investigated the changes in glenoid rim morphology, glenoid defect size, and bone fragment size from the first to the final CT.
    Results: At first CT, 51 shoulders showed no glenoid bone defect, 12 showed glenoid erosion, and 51 showed a glenoid bone fragment [33 small bone fragment (<7.5%) and 18 large bone fragment (≥7.5%); mean size: 4.9 ± 4.2% (0-17.9%)]. Among patients with glenoid defect (fragment and erosion), the mean glenoid defect was 5.4 ± 6.6% (0-26.6%); 49 were considered a small glenoid defect (<13.5%) and 14 were a large glenoid defect (≥13.5%). While all 14 shoulders with large glenoid defect had a bone fragment, small fragment was solely seen in 4 shoulders. At final CT, 23 of the 51 shoulders persisted without glenoid defect. The number of shoulders presenting glenoid erosion increased from 12 to 24, and the number of shoulders with bone fragment increased from 51 to 67 [36 small bone fragment and 31 large bone fragment; mean size: 5.1 ± 4.9% (0-21.1%)]. The prevalence of shoulders with no or a small bone fragment did not increase from first CT (71.4%) to final CT (65.9%;
    Conclusions: The prevalence of shoulders with a large glenoid defect and small bone fragment increases significantly after several instability events.
    Language English
    Publishing date 2023-04-10
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6383
    ISSN (online) 2666-6383
    DOI 10.1016/j.jseint.2023.03.008
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  3. Article ; Online: Secondary frozen shoulder after traumatic anterior shoulder instability.

    Harada, Yohei / Iwahori, Yusuke / Kajita, Yukihiro / Saito, Yutaka / Takahashi, Ryosuke / Deie, Masataka

    JSES international

    2019  Volume 4, Issue 1, Page(s) 72–76

    Abstract: ... to stiffness after traumatic anterior shoulder instability. Conservative treatment can be used as the first ... Background: Secondary frozen shoulder after traumatic anterior shoulder instability is rare ... the cases of 12 patients with secondary frozen shoulder after anterior shoulder dislocation or subluxation ...

    Abstract Background: Secondary frozen shoulder after traumatic anterior shoulder instability is rare. The therapeutic management and clinical outcome of this condition are not well known. This study aimed to investigate the characteristics of such rare cases and verify treatment outcomes.
    Methods: We reviewed the cases of 12 patients with secondary frozen shoulder after anterior shoulder dislocation or subluxation between April 2007 and March 2018. All patients underwent physical therapy along with an intra-articular injection. Patients with refractory stiffness received arthroscopic mobilization. The range of motion, Rowe score, and University of California, Los Angeles score were evaluated at the first and final visits. A telephone survey was performed to determine the long-term outcomes including recurrent instability, the Oxford Shoulder Score, and the Oxford Instability Score.
    Results: The mean age of patients at the first visit was 42.5 years. Two patients underwent surgical treatment, which revealed scar-like tissue of the anteroinferior capsule. The range of motion, Rowe score, and University of California, Los Angeles score significantly improved at a mean follow-up of 15 months. At a mean follow-up of 82 months, the telephone survey revealed recurrent instability in 1 patient who was conservatively treated; the average Oxford Shoulder Score and Oxford Instability Score were 46.4 and 43.2, respectively.
    Conclusions: The average patient age observed in this study was higher than the known peak age of traumatic anterior shoulder instability occurrence. Less activity, loss of capsule elasticity, or scarring after a capsular tear may lead to stiffness after traumatic anterior shoulder instability. Conservative treatment can be used as the first-line therapy, followed by effective arthroscopic mobilization when conservative treatment fails.
    Language English
    Publishing date 2019-12-16
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6383
    ISSN (online) 2666-6383
    DOI 10.1016/j.jses.2019.10.100
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  4. Article ; Online: Return to Professional Australian Rules Football After Surgery for Traumatic Anterior Shoulder Instability.

    Perret, Michael / Warby, Sarah / Brais, Godefroy / Hinse, Stephanie / Hoy, Sophie / Hoy, Gregory

    The American journal of sports medicine

    2021  Volume 49, Issue 11, Page(s) 3066–3075

    Abstract: Background: The treatment of traumatic anterior shoulder instability in professional Australian ... different procedures for traumatic anterior shoulder instability in professional AFL players.: Study ... of instability recurrence.: Purpose: To investigate return-to-sport (RTS) outcomes and complications after 2 ...

    Abstract Background: The treatment of traumatic anterior shoulder instability in professional Australian Football League (AFL) players is challenging, with an emphasis on early return to play and avoidance of instability recurrence.
    Purpose: To investigate return-to-sport (RTS) outcomes and complications after 2 different procedures for traumatic anterior shoulder instability in professional AFL players.
    Study design: Cohort study; Level of evidence, 3.
    Methods: We retrospectively reviewed our surgical database for professional AFL players who underwent capsulolabral stabilization or open Latarjet procedure by a single surgeon between 2006 and 2017. Outcomes included RTS, on-field performance, and complications. Between-group analyses for RTS and complications were estimated using Kaplan-Meier survival analyses. Within-group analyses for on-field performance data were performed using paired
    Results: A total of 58 capsulolabral stabilization procedures in 54 players and 32 Latarjet procedures in 29 players were included in the analysis; 93.1% of capsulolabral patients and 96.9% of Latarjet patients returned to professional AFL. The median RTS time was 6.8 months for the capsulolabral group and 7.3 months for the Latarjet group. There was no significant difference in RTS rates between the 2 groups (
    Conclusion: In this study, the median RTS in AFL players was approximately 7 months after capsulolabral and Latarjet surgery with no compromise to on-field performance. Instability-related complications occurred only in the capsulolabral group, and the incidence increased with time.
    MeSH term(s) Humans ; Australia/epidemiology ; Cohort Studies ; Joint Instability/surgery ; Retrospective Studies ; Shoulder ; Shoulder Dislocation ; Shoulder Joint ; Team Sports
    Language English
    Publishing date 2021-08-16
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 197482-8
    ISSN 1552-3365 ; 0363-5465
    ISSN (online) 1552-3365
    ISSN 0363-5465
    DOI 10.1177/03635465211029022
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  5. Article ; Online: Immobilisation in external rotation after first-time traumatic anterior shoulder instability reduces recurrent instability: a meta-analysis.

    Hurley, Eoghan T / Fried, Jordan W / Alaia, Michael J / Strauss, Eric J / Jazrawi, Laith M / Matache, Bogdan A

    Journal of ISAKOS : joint disorders & orthopaedic sports medicine

    2020  Volume 6, Issue 1, Page(s) 22–27

    Abstract: ... Immobilisation of the shoulder in external rotation after a traumatic first-time anterior shoulder ... to compare immobilisation in external versus internal rotation after first-time anterior shoulder ... displacement when the shoulder is placed in external rotation as compared with internal rotation.: Objective ...

    Abstract Importance: Cadaveric and MRI findings have demonstrated significantly less labral separation and displacement when the shoulder is placed in external rotation as compared with internal rotation.
    Objective: The purpose of the current study is to meta-analyse the randomised controlled trials in the literature to compare immobilisation in external versus internal rotation after first-time anterior shoulder dislocation.
    Evidence review: A literature search of MEDLINE, EMBASE and the Cochrane Library was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Randomised controlled trials comparing immobilisation in external rotation versus internal rotation for first-time anterior shoulder dislocation were included.
    Findings: Nine randomised controlled trials with 795 patients were included. The mean age of included patients was 29 years, 82.4% were male and the mean follow-up was 25.5 months. As compared with immobilisation in internal rotation, compliance was significantly higher (74.5% vs 67.4%, p=0.01), and the rate of recurrent dislocations was significantly lower (22.2% vs 33.4%, p=0.02) with immobilisation in external rotation. Additionally, in patients 20-40 years old the rate of recurrent dislocations was significantly lower in those treated with immobilisation in external rotation than internal rotation (12.1% vs 31.4%, p=0.006). Immobilisation in external rotation also resulted in a higher rate of return to preinjury level of play (60.1% vs 42.6%, p=0.0001).
    Conclusions and relevance: Immobilisation of the shoulder in external rotation after a traumatic first-time anterior shoulder dislocation results in a higher compliance rate, a lower recurrent dislocation rate and a higher rate of return to play as compared with immobilisation in internal rotation.
    Level of evidence: Level I.
    MeSH term(s) Adult ; Female ; Humans ; Immobilization/methods ; Joint Instability/physiopathology ; Joint Instability/therapy ; Male ; Orthopedic Procedures/methods ; Patient Compliance ; Randomized Controlled Trials as Topic ; Range of Motion, Articular ; Recurrence ; Return to Sport ; Rotation ; Shoulder Dislocation/physiopathology ; Shoulder Dislocation/therapy ; Shoulder Joint/injuries ; Shoulder Joint/physiopathology ; Young Adult
    Language English
    Publishing date 2020-12-23
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ISSN 2059-7762
    ISSN (online) 2059-7762
    DOI 10.1136/jisakos-2020-000511
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  6. Article ; Online: Predicting Recurrent Instability of the Shoulder (PRIS): A Valid Tool to Predict Which Patients Will Not Have Repeat Shoulder Instability After First-Time Traumatic Anterior Dislocation.

    Olds, Margie / Ellis, Richard / Kersten, Paula

    The Journal of orthopaedic and sports physical therapy

    2020  Volume 50, Issue 8, Page(s) 431–437

    Abstract: ... Instability of the Shoulder (PRIS) tool in people with a first-time traumatic anterior shoulder ... following first-time traumatic anterior shoulder dislocation. The PRIS tool cannot accurately predict ... available for 1-year follow-up, 57 (76%) did not have recurrent shoulder instability. With the PRIS tool cut ...

    Abstract Objective: To assess the sensitivity, specificity, and validity of the Predicting Recurrent Instability of the Shoulder (PRIS) tool in people with a first-time traumatic anterior shoulder dislocation.
    Design: Prospective cohort study.
    Methods: People with first-time traumatic anterior shoulder dislocation (n = 85), aged 16 to 40 years, were recruited within 12 weeks of their shoulder dislocation and followed prospectively for 1 year post injury. We calculated the sensitivity, specificity, negative predictive value, and positive predictive value of the PRIS tool.
    Results: Of the 75 participants available for 1-year follow-up, 57 (76%) did not have recurrent shoulder instability. With the PRIS tool cut point set at 0.895, the tool's sensitivity was 39% (95% confidence interval [CI]: 17.3%, 64.3%) and its specificity was 95% (95% CI: 85.4%, 98.9%). The area under the curve was 0.69 (95% CI: 0.55, 0.84;
    Conclusion: The PRIS tool can predict those who will not have further shoulder instability in the year following first-time traumatic anterior shoulder dislocation. The PRIS tool cannot accurately predict those who will have recurrent shoulder instability.
    MeSH term(s) Adolescent ; Adult ; Female ; Follow-Up Studies ; Humans ; Joint Instability/diagnosis ; Joint Instability/etiology ; Joint Instability/therapy ; Male ; Prognosis ; Prospective Studies ; Recurrence ; Risk Assessment/methods ; Sensitivity and Specificity ; Shoulder Dislocation/diagnosis ; Shoulder Dislocation/etiology ; Shoulder Dislocation/therapy ; Young Adult
    Language English
    Publishing date 2020-07-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604640-x
    ISSN 1938-1344 ; 0190-6011
    ISSN (online) 1938-1344
    ISSN 0190-6011
    DOI 10.2519/jospt.2020.9284
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  7. Article ; Online: Minimum 10-Year Clinical Outcomes After Arthroscopic 270° Labral Repair in Traumatic Shoulder Instability Involving Anterior, Inferior, and Posterior Labral Injury.

    Berthold, Daniel P / LeVasseur, Matthew R / Muench, Lukas N / Mancini, Michael R / Uyeki, Colin L / Lee, Julianna / Beitzel, Knut / Imhoff, Andreas B / Arciero, Robert A / Scheiderer, Bastian / Siebenlist, Sebastian / Mazzocca, Augustus D

    The American journal of sports medicine

    2021  Volume 49, Issue 14, Page(s) 3937–3944

    Abstract: ... outcomes and complication and redislocation rates in patients with traumatic shoulder instability involving ... scale for pain, and Single Assessment Numeric Evaluation (SANE). Western Ontario Shoulder Instability ... years, the clinical outcomes, complications, and recurrent instability in patients with 270° labral ...

    Abstract Background: Current literature reports highly satisfactory short- and midterm clinical outcomes in patients with arthroscopic 270° labral tear repairs. However, data remain limited on long-term clinical outcomes and complication and redislocation rates in patients with traumatic shoulder instability involving anterior, inferior, and posterior labral injury.
    Purpose: To investigate, at a minimum follow-up of 10 years, the clinical outcomes, complications, and recurrent instability in patients with 270° labral tears involving the anterior, inferior, and posterior labrum treated with arthroscopic stabilization using suture anchors.
    Study design: Case series; Level of evidence, 4.
    Methods: A retrospective outcomes study was completed for all patients with a minimum 10-year follow-up who underwent arthroscopic 270° labral tear repairs with suture anchors by a single surgeon. Outcome measures included pre- and postoperative Rowe score, American Shoulder and Elbow Surgeons (ASES) score, Simple Shoulder Test, visual analog scale for pain, and Single Assessment Numeric Evaluation (SANE). Western Ontario Shoulder Instability Index (WOSI) scores were collected postoperatively. Complication data were collected, including continued instability, subluxation or dislocation events, and revision surgery. Failure was defined as any cause of revision surgery.
    Results: In total, 21 patients (mean ± SD age, 27.1 ± 9.6 years) with 270° labral repairs were contacted at a minimum 10-year follow-up. All outcome measures showed statistically significant improvements as compared with those preoperatively: Rowe (53.9 ± 11.4 to 88.7 ± 8.9;
    Conclusion: Arthroscopic repairs of 270° labral tears involving the anterior, inferior, and posterior labrum have highly satisfactory clinical outcomes at 10 years, with complication and redislocation rates similar to those reported at 2 years. This suggests that repairs of extensile labral tears are effective in restoring and maintaining mechanical stability of the glenohumeral joint in the long term.
    MeSH term(s) Adolescent ; Adult ; Arthroscopy ; Humans ; Joint Instability/surgery ; Retrospective Studies ; Shoulder ; Shoulder Injuries ; Shoulder Joint/surgery ; Treatment Outcome ; Young Adult
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 197482-8
    ISSN 1552-3365 ; 0363-5465
    ISSN (online) 1552-3365
    ISSN 0363-5465
    DOI 10.1177/03635465211053632
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  8. Article ; Online: Recurrence Rate of Instability After Remplissage for Treatment of Traumatic Anterior Shoulder Instability: A Systematic Review in Treatment of Subcritical Glenoid Bone Loss.

    Liu, Joseph N / Gowd, Anirudh K / Garcia, Grant H / Cvetanovich, Gregory L / Cabarcas, Brandon C / Verma, Nikhil N

    Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association

    2018  Volume 34, Issue 10, Page(s) 2894–2907.e2

    Abstract: Purpose: To report outcomes after arthroscopic remplissage in patients with anterior shoulder ... instability and subcritical glenoid bone loss, specifically regarding recurrence of instability, return ... and Scopus databases. Forest plots were used to evaluate the overall values for recurrent instability ...

    Abstract Purpose: To report outcomes after arthroscopic remplissage in patients with anterior shoulder instability and subcritical glenoid bone loss, specifically regarding recurrence of instability, return to sport, and changes in range of motion.
    Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were used to perform a search using the PubMed, Embase, Cochrane Library, and Scopus databases. Forest plots were used to evaluate the overall values for recurrent instability, change in external rotation, and return to sport after arthroscopic Bankart repair with or without remplissage. The Methodological Index for Non-randomized Studies and Risk of Bias in Nonrandomized Studies-Interventions checklist were used to evaluate bias.
    Results: Twenty-two articles met the inclusion and exclusion criteria. The Methodological Index for Non-randomized Studies and Risk of Bias in Nonrandomized Studies-Interventions checklists deemed studies as acceptable quality with low bias. Among 694 patients (522 male and 106 female patients) undergoing remplissage, the mean age was 28.3 ± 5.3 years and the mean duration of follow-up was 32.5 ± 13.9 months. The recurrence rate of instability ranged from 0% to 20%. The change in external rotation in 90° of abduction ranged from -11.3° to -1.0°, and the change in external rotation with the arm fully adducted ranged from -8.0° to +4.5°. The overall rate of return to sport ranged from 56.9% to 100% after remplissage. The rate of return to sport at the preinjury level ranged from 41.7% to 100%. In addition, arthroscopic remplissage in addition to Bankart repair had a reduced odds of recurrent instability developing, ranging from 0.07 to 0.88, when compared with isolated Bankart repair.
    Conclusions: Arthroscopic remplissage combined with Bankart repair is an effective procedure in the treatment of patients with engaging Hill-Sachs lesions and minimal glenoid bone loss. Patients can expect favorable rates of recurrent instability with a negligible loss of external rotation when compared with isolated Bankart repair. Treatment algorithms may be updated to include this procedure for engaging Hill-Sachs lesions, measuring between 20% and 40% in volume, with subcritical (<20%) glenoid bone loss.
    Level of evidence: Level IV, systematic review of Level III and IV studies.
    MeSH term(s) Arthroscopy/methods ; Bankart Lesions/surgery ; Glenoid Cavity/pathology ; Humans ; Joint Instability/surgery ; Recurrence ; Shoulder Dislocation/surgery ; Shoulder Joint/surgery
    Language English
    Publishing date 2018-09-05
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 632528-2
    ISSN 1526-3231 ; 0749-8063
    ISSN (online) 1526-3231
    ISSN 0749-8063
    DOI 10.1016/j.arthro.2018.05.031
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  9. Article: Indication for Computed Tomography Scan in Shoulder Instability: Sensitivity and Specificity of Standard Radiographs to Predict Bone Defects After Traumatic Anterior Glenohumeral Instability.

    Delage Royle, Audrey / Balg, Frédéric / Bouliane, Martin J / Canet-Silvestri, Fanny / Garant-Saine, Laurianne / Sheps, David M / Lapner, Peter / Rouleau, Dominique M

    Orthopaedic journal of sports medicine

    2017  Volume 5, Issue 10, Page(s) 2325967117733660

    Abstract: ... of recurrent shoulder instability.: Study design: Cohort study (diagnosis); Level of evidence, 2.: Methods ... in the treatment algorithm for accurate quantification of bone loss to prevent high rates of recurrent instability. ... A true anteroposterior (AP) view, alone and in combination with an axillary view, was used to evaluate ...

    Abstract Background: Quantifying glenohumeral bone loss is key in preoperative surgical planning for a successful Bankart repair.
    Hypothesis: Simple radiographs can accurately measure bone defects in cases of recurrent shoulder instability.
    Study design: Cohort study (diagnosis); Level of evidence, 2.
    Methods: A true anteroposterior (AP) view, alone and in combination with an axillary view, was used to evaluate the diagnostic properties of radiographs compared with computed tomography (CT) scan, the current gold standard, to predict significant bone defects in 70 patients. Sensitivity, specificity, and positive and negative predictive values were evaluated and compared.
    Results: Detection of glenoid bone loss on plain film radiographs, with and without axillary view, had a sensitivity of 86% for both views and a specificity of 73% and 64% with and without the axillary view, respectively. For detection of humeral bone loss, the sensitivity was 8% and 17% and the specificity was 98% and 91% with and without the axillary view, respectively. Regular radiographs would have missed 1 instance of significant bone loss on the glenoid side and 20 on the humeral side. Interobserver reliabilities were moderate for glenoid detection (κ = 0.473-0.503) and poor for the humeral side (κ = 0.278-0.336).
    Conclusion: Regular radiographs showed suboptimal sensitivity, specificity, and reliability. Therefore, CT scan should be considered in the treatment algorithm for accurate quantification of bone loss to prevent high rates of recurrent instability.
    Language English
    Publishing date 2017-10-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2706251-X
    ISSN 2325-9671
    ISSN 2325-9671
    DOI 10.1177/2325967117733660
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  10. Article ; Online: Periostin Is a Biomarker for Anterior Shoulder Instability: Proteomic Analysis of Synovial Fluid.

    Galvin, Joseph W / Milam, Rachel J / Patterson, Brendan M / Nepola, James V / Buckwalter, Joseph A / Wolf, Brian R / Say, Felicity M / Free, Katherine E / Yohannes, Elizabeth

    The American journal of sports medicine

    2024  , Page(s) 3635465241246258

    Abstract: ... as a significant target in anterior shoulder instability is a novel finding. Therefore, further study is warranted ... analysis of synovial fluid in patients with shoulder instability may improve our understanding of proteins ... of synovial fluid in patients with shoulder instability.: Study design: Descriptive laboratory study.: Methods ...

    Abstract Background: The incremental biological changes in the synovial microenvironment of the shoulder in acute and chronic instability that may contribute to joint degeneration are poorly understood. Proteomic analysis of synovial fluid in patients with shoulder instability may improve our understanding of proteins that are shed into shoulder synovial fluid after an injury.
    Hypothesis: Injury-specific factors such as the direction of instability and the severity of glenoid and humeral bone loss are associated with the proteome of synovial fluid in patients with shoulder instability.
    Study design: Descriptive laboratory study.
    Methods: Synovial fluid lavage samples were compared between patients with anterior (n = 12) and posterior (n = 8) instability and those without instability (n = 5). Synovial proteins were identified with liquid chromatography-tandem mass spectrometry. Orthogonal validation of protein targets found to be significant on tandem mass spectrometry was performed in a separate set of prospective patients with Western blotting. Data were processed and analyzed, and
    Results: A total of 25 patients were included. Tandem mass spectrometry identified 720 protein groups in synovial fluid of patients with shoulder instability. There were 4 synovial proteins that were significantly expressed in patients with anterior instability relative to posterior instability: periostin (POSTN) (adjusted
    Conclusion: Proteomic analysis enriched our understanding of proteins that were secreted into shoulder synovial fluid of patients with shoulder instability. The identification of POSTN, a proinflammatory catabolic protein involved with tissue remodeling and repair, as a significant target in anterior shoulder instability is a novel finding. Therefore, further study is warranted to determine the role that POSTN may play in the progression of bone loss and posttraumatic osteoarthritis.
    Clinical relevance: Proteomic analysis of synovial fluid in patients with shoulder instability improved our understanding of this abnormality after an injury.
    Language English
    Publishing date 2024-05-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 197482-8
    ISSN 1552-3365 ; 0363-5465
    ISSN (online) 1552-3365
    ISSN 0363-5465
    DOI 10.1177/03635465241246258
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