Article ; Online: Recommendations on the management of adult patients with rheumatic diseases in the context of SARS-CoV-2/COVID-19 infection. Colombian Association of Rheumatology.
Reumatologia clinica
2020 Volume 16, Issue 6, Page(s) 437–446
Abstract: ... the infection, and to suspend it in patients with a diagnosis of SARS-CoV-2/COVID-19. ... Objective: To produce recommendations for patients with rheumatological diseases receiving ... in rheumatology is to continue with immunomodulatory or immunosuppressive therapies in patients who do not have ...
| Title translation | Recomendaciones sobre el manejo de pacientes adultos con enfermedades reumáticas en el contexto de la infección por SARS-CoV-2/COVID-19. Asociación Colombiana de Reumatología. |
|---|---|
| Abstract | Objective: To produce recommendations for patients with rheumatological diseases receiving immunomodulatory and immunosuppressive therapies (conventional drugs, biologicals, and small molecules) during the COVID-19 pandemic. Materials and methods: The recommendations were determined using the Delphi method as an agreement tool. A panel of experts was formed, with academic backgrounds and research experience in rheumatology. A literature search was conducted and 42 questions were generated. The level of agreement was made with 80% of approval by the participants. Results: A group of eleven rheumatologists from 7 cities in the country participated. The response rate was 100% for the three consultation rounds. In the first round, agreement was reached on 35 questions, on 37 in the second round, and on 42 questions in the third round. Conclusion: The recommendation for the majority of the pharmacological treatments used in rheumatology is to continue with immunomodulatory or immunosuppressive therapies in patients who do not have the infection, and to suspend it in patients with a diagnosis of SARS-CoV-2/COVID-19. |
| MeSH term(s) | Adult ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal/therapeutic use ; Antimalarials/adverse effects ; Antimalarials/therapeutic use ; Antirheumatic Agents/adverse effects ; Antirheumatic Agents/therapeutic use ; Betacoronavirus ; Biological Products/adverse effects ; Biological Products/therapeutic use ; COVID-19 ; Clinical Trials as Topic ; Colombia ; Coronavirus Infections/complications ; Coronavirus Infections/drug therapy ; Delphi Technique ; Drug Interactions ; Drug Repositioning ; Glucocorticoids/adverse effects ; Glucocorticoids/therapeutic use ; Humans ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/adverse effects ; Immunologic Factors/therapeutic use ; Immunosuppressive Agents/adverse effects ; Immunosuppressive Agents/therapeutic use ; Multicenter Studies as Topic ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/drug therapy ; Rheumatic Diseases/complications ; Rheumatic Diseases/drug therapy ; SARS-CoV-2 |
| Chemical Substances | Anti-Inflammatory Agents, Non-Steroidal ; Antibodies, Monoclonal ; Antimalarials ; Antirheumatic Agents ; Biological Products ; Glucocorticoids ; Immunoglobulins, Intravenous ; Immunologic Factors ; Immunosuppressive Agents |
| Keywords | covid19 |
| Language | Spanish |
| Publishing date | 2020-07-28 |
| Publishing country | Spain |
| Document type | Consensus Development Conference ; Journal Article ; Practice Guideline ; Review |
| ISSN | 2173-5743 |
| ISSN (online) | 2173-5743 |
| DOI | 10.1016/j.reuma.2020.06.011 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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