Article ; Online: Short-term cardiac outcome in survivors of COVID-19: a systematic study after hospital discharge.
Clinical research in cardiology : official journal of the German Cardiac Society
2021 Volume 110, Issue 7, Page(s) 1063–1072
Abstract: ... involvement has been reported during infection. The short-term cardiac outcome in survivors of COVID-19 is not ... Survivors of COVID-19 were compared with 105 matched controls. We also compared the cardiac outcome and lung ... of survivors of COVID-19, nor cardiac differences were detected between patients who had different severity ...
| Abstract | Background: COVID-19 has caused considerable morbidity and mortality worldwide and cardiac involvement has been reported during infection. The short-term cardiac outcome in survivors of COVID-19 is not known. Objective: To examine the heart of patients who survived COVID-19 and to compare the cardiac outcome between patients who recovered from mild-to-moderate or severe illness. Methods: With use of ECG and echocardiography, we examined the heart of 105 patients who had been hospitalized with COVID-19 and were consecutively recruited after hospital discharge while attending follow-up visits. Survivors of COVID-19 were compared with 105 matched controls. We also compared the cardiac outcome and lung ultrasound scan between COVID-19 patients who had mild-to-moderate or severe illness. Results: Cardiac data were collected a median of 41 days from the first detection of COVID-19. Symptoms were present in a low percentage of patients. In comparison with matched controls, no considerable structural or functional differences were observed in the heart of survivors of COVID-19. Lung ultrasound scan detected significantly greater residual pulmonary involvement in COVID-19 patients who had recovered from severe than mild-to-moderate illness. No significant differences were detected in ECG tracings nor were found in the left and right ventricular function of patients who had recovered from mild-to-moderate or severe illness. Conclusions: In a short-term follow-up, no abnormalities were identified in the heart of survivors of COVID-19, nor cardiac differences were detected between patients who had different severity of illness. With the limitations of a cross-sectional study, these findings suggest that patients who recover from COVID-19 do not have considerable cardiac sequelae. |
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| MeSH term(s) | Adult ; Aged ; COVID-19/complications ; Cross-Sectional Studies ; Echocardiography ; Electrocardiography ; Female ; Heart Diseases/epidemiology ; Heart Diseases/physiopathology ; Heart Diseases/virology ; Humans ; Male ; Middle Aged ; Patient Discharge ; Severity of Illness Index ; Survivors | |||||
| Language | English | |||||
| Publishing date | 2021-01-22 | |||||
| Publishing country | Germany | |||||
| Document type | Journal Article ; Observational Study | |||||
| ZDB-ID | 2213295-8 | |||||
| ISSN | 1861-0692 ; 1861-0684 | |||||
| ISSN (online) | 1861-0692 | |||||
| ISSN | 1861-0684 | |||||
| DOI | 10.1007/s00392-020-01800-z | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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