Article ; Online: Diabetes mellitus as a risk factor for SARS-CoV-2 test positivity in Mexico: A propensity score matched study.
Diabetes research and clinical practice
2021 Volume 178, Page(s) 108953
Abstract: ... tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score ... of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes ... for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection. ...
Abstract | Aims: We sought to investigate whether individuals with diabetes have a higher likelihood of testing positive for SARS-CoV-2, as a proxy for infection risk, than individuals without diabetes. Methods: We conducted a cross-sectional study of publicly available data among a Mexican population, totaling 2,314,022 adults ≥ 18 years who underwent SARS-CoV-2 testing between March 1 and December 20, 2020. We used 1:1 nearest neighborhood propensity score matching by diabetes status to account for confounding among those with and without diabetes. Results: In the overall study population, 1,057,779 (45.7%) individuals tested positive for SARS-CoV-2 and 270,486 (11.7%) self-reported diabetes. After propensity score matching, patient characteristics were well-balanced, with 150,487 patients in the diabetes group (mean [SD] age 55.9 [12.7] years; 51.3% women) and 150,487 patients in the no diabetes group (55.5 [13.3] years; 50.3% women). The strictest matching algorithm (1:1 nearest neighbor) showed that compared to individuals without diabetes, having diabetes was associated with 9.0% higher odds of having a positive SARS-CoV-2 test (OR 1.09 [95% CI: 1.08-1.10]). Conclusions: Presence of diabetes was associated with higher odds of testing positive for SARS-CoV-2, which could have important implications for risk mitigation efforts for people with diabetes at risk of SARS-CoV-2 infection. |
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MeSH term(s) | Adolescent ; Adult ; Aged ; COVID-19/diagnosis ; COVID-19 Testing ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Propensity Score ; Risk Factors ; SARS-CoV-2 ; Young Adult | |||||
Language | English | |||||
Publishing date | 2021-07-21 | |||||
Publishing country | Ireland | |||||
Document type | Journal Article | |||||
ZDB-ID | 632523-3 | |||||
ISSN | 1872-8227 ; 0168-8227 | |||||
ISSN (online) | 1872-8227 | |||||
ISSN | 0168-8227 | |||||
DOI | 10.1016/j.diabres.2021.108953 | |||||
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Database | MEDical Literature Analysis and Retrieval System OnLINE |
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