Article: Coinfections in Patients Hospitalized with COVID-19: A Descriptive Study from the United Arab Emirates.
2021 Volume 14, Page(s) 2289–2296
Abstract: Purpose: Microbial coinfections in COVID-19 patients carry a risk of poor outcomes. This study ... Khalifa General Hospital Umm Al Quwain.: Results: Of 29,802 patients hospitalized with COVID-19, 392 (1 ... occurrence of coinfections among patients with COVID-19 in our setting, clinical outcomes remained poor ...
| Abstract | Purpose: Microbial coinfections in COVID-19 patients carry a risk of poor outcomes. This study aimed to characterize the clinical and microbiological profiles of coinfections in patients with COVID-19. Methods: A retrospective review of the clinical and laboratory records of COVID-19 patients with laboratory-confirmed infections with bacteria, fungi, and viruses was conducted. Only adult COVID-19 patients hospitalized at participating health-care facilities between February 1 and July 31, 2020 were included. Data were collected from the centralized electronic system of Dubai Health Authority hospitals and Sheikh Khalifa General Hospital Umm Al Quwain. Results: Of 29,802 patients hospitalized with COVID-19, 392 (1.3%) had laboratory-confirmed coinfections. The mean age of patients with coinfections was 49.3±12.5 years, and a majority were male (n=330 of 392, 84.2%). Mean interval to commencement of empirical antibiotics was 1.2±3.6) days postadmission, with ceftriaxone, azithromycin, and piperacillin-tazobactam the most commonly used. Median interval between admission and first positive culture (mostly from blood, endotracheal aspirates, and urine specimens) was 15 (IQR 8-25) days. Conclusion: Despite the low occurrence of coinfections among patients with COVID-19 in our setting, clinical outcomes remained poor. Predominance of Gram-negative pathogens, emergence of |
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| Language | English |
| Publishing date | 2021-06-21 |
| Publishing country | New Zealand |
| Document type | Journal Article |
| ZDB-ID | 2494856-1 |
| ISSN | 1178-6973 |
| ISSN | 1178-6973 |
| DOI | 10.2147/IDR.S314029 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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