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  1. Article ; Online: Age, neutrophil lymphocyte ratio, and radiographic assessment of the quantity of lung edema (RALE) score to predict in-hospital mortality in COVID-19 patients: a retrospective study.

    Sensusiati, Anggraini Dwi / Amin, Muhammad / Nasronudin, Nasronudin / Rosyid, Alfian Nur / Ramadhan, Nanda Aulya / Lathifah, Rofida / Puspitasari, Eva / Wahyuningtyas, Ria Indah / Soebakti, Erika

    F1000Research

    2020  Volume 9, Page(s) 1286

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Adult ; Age Factors ; Aged ; COVID-19/diagnosis ; COVID-19/mortality ; Edema/diagnostic imaging ; Female ; Hospital Mortality ; Humans ; Lung/diagnostic imaging ; Lung/physiopathology ; Lymphocytes/cytology ; Male ; Middle Aged ; Neutrophils/cytology ; Respiratory Sounds ; Retrospective Studies
    Language English
    Publishing date 2020-10-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 2699932-8
    ISSN 2046-1402 ; 2046-1402
    ISSN (online) 2046-1402
    ISSN 2046-1402
    DOI 10.12688/f1000research.26723.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Age, neutrophil lymphocyte ratio, and radiographic assessment of the quantity of lung edema (RALE) score to predict in-hospital mortality in COVID-19 patients

    Anggraini Dwi Sensusiati / Muhammad Amin / Nasronudin Nasronudin / Alfian Nur Rosyid / Nanda Aulya Ramadhan / Rofida Lathifah / Eva Puspitasari / Ria Indah Wahyuningtyas / Erika Soebakti

    F1000Research, Vol

    a retrospective study [version 2; peer review: 2 approved]

    2021  Volume 9

    Abstract: ... Conclusions Age, NLR score and RALE score were associated with mortality of COVID-19 patients in the hospital ... assessment of the quantity of lung edema (RALE) score, and mortality. Data were analyzed using SPSS 25.0 ... This study aimed to assess the factors associated with hospital mortality of COVID-19 patients, and develop ...

    Abstract Background: Available data suggest that case fatality rate of COVID-19 patients in Surabaya is higher than global cases. Thus, it is important to identify risk factors to prevent the mortality. This study aimed to assess the factors associated with hospital mortality of COVID-19 patients, and develop a prediction score based on these findings. Methods: We analyzed 111 patients, who were diagnosed with COVID-19 based on reverse-transcriptase polymerase chain reaction. The following patient characteristics were obtained from records: age, gender, type of symptoms, onset of symptoms, neutrophil lymphocyte ratio (NLR), absolute lymphocyte count, chest x-ray abnormalities, lung involvement, type of lesion, radiographic assessment of the quantity of lung edema (RALE) score, and mortality. Data were analyzed using SPSS 25.0. Results Multivariate analysis showed that age >50 years (p=0.043), NLR score >5.8 (p=0.016) and RALE score >2 (p=0.002) can predict the mortality of COVID-19 patients in the hospital. ROC curve analysis of the score ability to predict mortality showed an area under the curve of 0.794. The cut-off point is 4.5, with a sensitivity of 96.7% and specificity of 49.4% to predict the mortality of COVID-19 patient in the hospital. Conclusions Age, NLR score and RALE score were associated with mortality of COVID-19 patients in the hospital and might be used as a predictor for mortality of COVID-19 patients in health care centre where radiologists are available. The prediction score may be useful for frontline physicians to effectively manage patients with a higher score to prevent mortality.
    Keywords Medicine ; R ; Science ; Q
    Subject code 310
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher F1000 Research Ltd
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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