Article: Need for Caution in the Diagnosis of Radiation Pneumonitis During the COVID-19 Pandemic.
Advances in radiation oncology
2020 Volume 5, Issue 4, Page(s) 617–620
Abstract: ... but ultimately diagnosed with COVID-19 showed ground-glass opacities mostly pronounced outside the radiation ... 19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiation therapy with clinical and ... with symptoms of RP during the intensification of a regional COVID-19 epidemic to report on their clinical ...
| Abstract | Purpose: Patients with cancer are at high risk for mortality from coronavirus disease 2019 (COVID-19). Radiation pneumonitis (RP) is a common toxicity of thoracic radiation therapy with clinical and imaging features that overlap with those of COVID-19; however, RP is treated with high-dose corticosteroids, which may exacerbate COVID-19-associated lung injury. We reviewed patients who presented with symptoms of RP during the intensification of a regional COVID-19 epidemic to report on their clinical course and COVID-19 testing results. Methods and materials: The clinical course and chest computed tomography (CT) imaging findings of consecutive patients who presented with symptoms of RP in March 2020 were reviewed. The first regional COVID-19 case was diagnosed on March 1, 2020. All patients underwent COVID-19 qualitative RNA testing. Results: Four patients with clinical suspicion for RP were assessed. Three out of 4 patients tested positive for COVID-19. All patients presented with symptoms of cough and dyspnea. Two patients had a fever, of whom only 1 tested positive for COVID-19. Two patients started on an empirical high-dose corticosteroid taper for presumed RP, but both had clinical deterioration and ultimately tested positive for COVID-19 and required hospitalization. Chest CT findings in patients suspected of RP but ultimately diagnosed with COVID-19 showed ground-glass opacities mostly pronounced outside the radiation field. Conclusions: As this pandemic continues, patients with symptoms of RP require diagnostic attention. We recommend that patients suspected of RP be tested for COVID-19 before starting empirical corticosteroids and for careful attention to be paid to chest CT imaging to prevent potential exacerbation of COVID-19 in these high-risk patients. |
|---|---|
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-05-05 |
| Publishing country | United States |
| Document type | Journal Article |
| ISSN | 2452-1094 |
| ISSN | 2452-1094 |
| DOI | 10.1016/j.adro.2020.04.015 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.