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  1. TI=Spectrum of cystic neoplasms of the pancreas and their surgical management
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  1. Article: Spectrum of cystic neoplasms of the pancreas and their surgical management.

    Sheehan, Maureen K / Beck, Kimberly / Pickleman, Jack / Aranha, Gerard V

    Archives of surgery (Chicago, Ill. : 1960)

    2003  Volume 138, Issue 6, Page(s) 657–60; discussion 660–2

    Abstract: ... 24 men) underwent surgical resection of a cystic neoplasm of the pancreas from January 1992 ... neoplasms of the pancreas are divided into the following 4 main groups: serous cystic neoplasms, mucinous cystic neoplasms ... our experience with cystic neoplasms of the pancreas at our institution from January 1992 through September 2002 ...

    Abstract Background: Owing to increased awareness and the widespread use of abdominal ultrasonography and computed tomography, an increasing number of cystic neoplasms are being identified. Cystic neoplasms of the pancreas are divided into the following 4 main groups: serous cystic neoplasms, mucinous cystic neoplasms, solid pseudopapillary neoplasms, and intraductal pancreatic mucinous neoplasms.
    Objective: To review our experience with cystic neoplasms of the pancreas at our institution from January 1992 through September 2002.
    Methods: Medical records were reviewed for age, sex, clinical signs and symptoms, diagnosis, surgical treatment, morbidity, mortality, and histologic features.
    Results: Seventy-three patients (49 women and 24 men) underwent surgical resection of a cystic neoplasm of the pancreas from January 1992 through September 2002. The most common presenting symptom was abdominal pain. Other symptoms included nausea, emesis, weight loss, jaundice, and pancreatitis. Most patients (73%) had no complications. The most common complication (10%) was pancreatic fistula. There were 3 deaths.
    Conclusions: Cystic neoplasms of the pancreas are an increasing entity. Long-term survival of patients with these tumors is generally better than that of patients with adenocarcinoma of the pancreas and mandates aggressive resectional therapy in most patients. Resection of these tumors can be done with resultant low morbidity and mortality rates.
    MeSH term(s) Carcinoma, Pancreatic Ductal/diagnosis ; Carcinoma, Pancreatic Ductal/surgery ; Female ; Humans ; Male ; Neoplasms, Cystic, Mucinous, and Serous/diagnosis ; Neoplasms, Cystic, Mucinous, and Serous/surgery ; Pancreatectomy/methods ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/surgery ; Retrospective Studies ; Tomography, X-Ray Computed
    Language English
    Publishing date 2003-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80055-7
    ISSN 1538-3644 ; 0004-0010 ; 0096-6908 ; 0272-5533
    ISSN (online) 1538-3644
    ISSN 0004-0010 ; 0096-6908 ; 0272-5533
    DOI 10.1001/archsurg.138.6.657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Spectrum and Classification of Cystic Neoplasms of the Pancreas.

    Greer, Jonathan B / Ferrone, Cristina R

    Surgical oncology clinics of North America

    2016  Volume 25, Issue 2, Page(s) 339–350

    Abstract: ... neoplasms of the pancreas are found. Intraductal papillary mucinous neoplasms and mucinous cystic neoplasms are the most ... common. The revised Sendai guidelines provide a safe algorithm for expectant management of certain cystic ... As patients are living longer and axial imaging is more widespread, increasing numbers of cystic ...

    Abstract As patients are living longer and axial imaging is more widespread, increasing numbers of cystic neoplasms of the pancreas are found. Intraductal papillary mucinous neoplasms and mucinous cystic neoplasms are the most common. The revised Sendai guidelines provide a safe algorithm for expectant management of certain cystic neoplasms; however, studies are ongoing to identify further subgroups that can be treated nonoperatively. For those patients with high-risk clinical features or symptoms, surgical resection can be performed safely at high-volume pancreatic centers. Accurate diagnosis is critical for accurate decision making.
    MeSH term(s) Humans ; Pancreas/pathology ; Pancreatic Cyst/classification ; Pancreatic Cyst/pathology ; Pancreatic Neoplasms/classification ; Pancreatic Neoplasms/pathology
    Language English
    Publishing date 2016-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1196919-2
    ISSN 1558-5042 ; 1055-3207
    ISSN (online) 1558-5042
    ISSN 1055-3207
    DOI 10.1016/j.soc.2015.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The changing spectrum of surgically treated cystic neoplasms of the pancreas.

    Plichta, Jennifer K / Brosius, Jacqueline A / Pappas, Sam G / Abood, Gerard J / Aranha, Gerard V

    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery

    2015  Volume 2015, Page(s) 791704

    Abstract: ... to evaluate the changes in their surgical management. Methods. Patients with pancreatic cystic lesions ... who underwent surgical resection from 2003 to 2013 were identified. Clinicopathologic factors were analyzed and ... included 18 serous, 47 mucinous, 11 pseudopapillary, and 58 intraductal papillary mucinous neoplasms (IPMN ...

    Abstract Introduction. While the incidence of pancreatic cystic lesions has steadily increased, we sought to evaluate the changes in their surgical management. Methods. Patients with pancreatic cystic lesions who underwent surgical resection from 2003 to 2013 were identified. Clinicopathologic factors were analyzed and compared to a similar cohort from 1992 to 2002. Results. There were 134 patients with pancreatic cystic lesions who underwent surgical resection from 2003 to 2013, compared to 73 from 1992 to 2002. The most common preoperative imaging was a CT scan, although 66% underwent EUS and 63% underwent biopsy. Pathology included 18 serous, 47 mucinous, 11 pseudopapillary, and 58 intraductal papillary mucinous neoplasms (IPMN). In comparing cohorts, there were significantly fewer serous lesions and more IPMN. Postoperative complication rates were similar, and perioperative mortality rates were comparable. Conclusion. There has been a dramatic change in surgically treated pancreatic cystic tumors over the past two decades. Our data suggests that the incorporation of new imaging and diagnostic tests has led to greater detection of cystic tumors and a decreased rate of potentially unnecessary resections. Therefore, all patients with cystic pancreatic lesions should undergo a focused CT-pancreas, and an EUS biopsy should be considered, in order to best select those that would benefit from surgical resection.
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1025964-8
    ISSN 1607-8462 ; 0894-8569
    ISSN (online) 1607-8462
    ISSN 0894-8569
    DOI 10.1155/2015/791704
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The spectrum of serous cystadenoma of the pancreas. Clinical, pathologic, and surgical aspects.

    Pyke, C M / van Heerden, J A / Colby, T V / Sarr, M G / Weaver, A L

    Annals of surgery

    1992  Volume 215, Issue 2, Page(s) 132–139

    Abstract: ... because of our current inability to reliably differentiate many of these benign neoplasms from malignant cystic ... with von Hippel-Lindau syndrome. The current role for conservative management remains questionable ... neoplasms of the pancreas. ...

    Abstract Serous cystadenoma of the pancreas is a rare lesion thought to be almost invariably benign. Since 1978, 211 cases have been reported in the literature. Some have been recognized by computed tomography (CT) when small and asymptomatic. The authors have reviewed their experience with 40 patients (median follow-up of 1.9 years, maximum of 22.2 years) from 1936 to 1991. One third (13) were asymptomatic, of whom eight (20%) were discovered intraoperatively. Of those 20 who had CT, an unequivocal preoperative diagnosis was reached in none. Needle biopsy proved accurate in two patients. Endoscopic retrograde cholangiopancreatography (ERCP) and biopsy were performed with diagnostic success on one occasion. Three patients presented acutely. The tumor was resected in 90%, with an operative mortality rate of 10%. Enucleation of the tumor without formal anatomic pancreatectomy necessitated reoperation for complications in four of eight patients. Survival after successful resection paralleled expected survival. Serous cystadenoma may be associated with von Hippel-Lindau syndrome. The current role for conservative management remains questionable because of our current inability to reliably differentiate many of these benign neoplasms from malignant cystic neoplasms of the pancreas.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Cystadenoma/complications ; Cystadenoma/etiology ; Cystadenoma/pathology ; Cystadenoma/surgery ; Female ; Humans ; Male ; Middle Aged ; Pancreatic Neoplasms/complications ; Pancreatic Neoplasms/etiology ; Pancreatic Neoplasms/pathology ; Pancreatic Neoplasms/surgery ; Prognosis ; Survival Analysis
    Language English
    Publishing date 1992-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/00000658-199202000-00007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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