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  1. Article ; Online: Understanding COVID-19 Acute Respiratory Distress Syndrome.

    Singh, Anchit Raj / Kumar, Raj / Sinha, Anwita

    Annals of the American Thoracic Society

    2021  Volume 19, Issue 1, Page(s) 150

    MeSH term(s) COVID-19 ; Humans ; Respiratory Distress Syndrome/diagnosis ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202104-486LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5828: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Understanding the Role of Mesenchymal Stromal Cells in Treating COVID-19 Acute Respiratory Distress Syndrome.

    O'Kane, Cecilia M / Matthay, Michael A

    American journal of respiratory and critical care medicine

    2022  Volume 207, Issue 3, Page(s) 231–233

    MeSH term(s) Humans ; COVID-19 ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2 ; Mesenchymal Stem Cells
    Language English
    Publishing date 2022-10-03
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202209-1838ED
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Understanding the pathophysiology of typical acute respiratory distress syndrome and severe COVID-19.

    Ball, Lorenzo / Silva, Pedro Leme / Giacobbe, Daniele Roberto / Bassetti, Matteo / Zubieta-Calleja, Gustavo R / Rocco, Patricia R M / Pelosi, Paolo

    Expert review of respiratory medicine

    2022  Volume 16, Issue 4, Page(s) 437–446

    Abstract: Introduction: Typical acute respiratory distress syndrome (ARDS) and severe coronavirus-19 (COVID ... of COVID-19-related acute hypoxemic respiratory failure that require attention. Two models have been ... proposed to describe the mechanisms of respiratory failure associated with typical ARDS and severe COVID-19 ...

    Abstract Introduction: Typical acute respiratory distress syndrome (ARDS) and severe coronavirus-19 (COVID-19) pneumonia share complex pathophysiology, a high mortality rate, and an unmet need for efficient therapeutics.
    Areas covered: This review discusses the current advances in understanding the pathophysiologic mechanisms underlying typical ARDS and severe COVID-19 pneumonia, highlighting specific aspects of COVID-19-related acute hypoxemic respiratory failure that require attention. Two models have been proposed to describe the mechanisms of respiratory failure associated with typical ARDS and severe COVID-19 pneumonia.
    Expert opinion: ARDS is defined as a syndrome rather than a distinct pathologic entity. There is great heterogeneity regarding the pathophysiologic, clinical, radiologic, and biological phenotypes in patients with ARDS, challenging clinicians, and scientists to discover new therapies. COVID-19 has been described as a cause of pulmonary ARDS and has reopened many questions regarding the pathophysiology of ARDS itself. COVID-19 lung injury involves direct viral epithelial cell damage and thrombotic and inflammatory reactions. There are some differences between ARDS and COVID-19 lung injury in aspects of aeration distribution, perfusion, and pulmonary vascular responses.
    MeSH term(s) COVID-19/complications ; Humans ; Lung/pathology ; Lung Injury ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency ; SARS-CoV-2
    Language English
    Publishing date 2022-03-30
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2479146-5
    ISSN 1747-6356 ; 1747-6348
    ISSN (online) 1747-6356
    ISSN 1747-6348
    DOI 10.1080/17476348.2022.2057300
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Reply: Understanding COVID-19 Acute Respiratory Distress Syndrome: New Pathogen, Same Heterogeneous Syndrome.

    Drohan, Callie / Bain, William / Kitsios, Georgios D

    Annals of the American Thoracic Society

    2021  Volume 19, Issue 1, Page(s) 151–160

    MeSH term(s) COVID-19 ; Humans ; Respiratory Distress Syndrome/diagnosis ; SARS-CoV-2
    Language English
    Publishing date 2021-06-17
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 2717461-X
    ISSN 2325-6621 ; 1943-5665 ; 2325-6621
    ISSN (online) 2325-6621 ; 1943-5665
    ISSN 2325-6621
    DOI 10.1513/AnnalsATS.202106-650LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5828: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Rapid Progression to Acute Respiratory Distress Syndrome: Review of Current Understanding of Critical Illness from COVID-19 Infection.

    Goh, Ken J / Choong, Mindy Cm / Cheong, Elizabeth Ht / Kalimuddin, Shirin / Duu Wen, Sewa / Phua, Ghee Chee / Chan, Kian Sing / Haja Mohideen, Salahudeen

    Annals of the Academy of Medicine, Singapore

    2020  Volume 49, Issue 3, Page(s) 108–118

    Abstract: ... rapidly worsening respiratory failure and acute respiratory distress syndrome (ARDS) that required ... The coronavirus disease 2019 (COVID-19) outbreak that started in Wuhan, Hubei province, China ... countries as of 7 March 2020. We report a case of COVID-19 infection in a 64-year-old man who developed ...

    Abstract The coronavirus disease 2019 (COVID-19) outbreak that started in Wuhan, Hubei province, China in December 2019 has now extended across the globe with >100,000 cases and 3,000 deaths reported in 93 countries as of 7 March 2020. We report a case of COVID-19 infection in a 64-year-old man who developed rapidly worsening respiratory failure and acute respiratory distress syndrome (ARDS) that required intubation. As the clinical spectrum of COVID-19 ranges widely from mild illness to ARDS with a high risk of mortality, there is a need for more research to identify early markers of disease severity. Current evidence suggests that patients with advanced age, pre-existing comorbidities or dyspnoea should be closely monitored, especially at 1-2 weeks after symptom onset. It remains to be seen if laboratory findings such as lymphopenia or elevated lactate dehydrogenase may serve as early surrogates for critical illness or markers of disease recovery. Management of ARDS in COVID-19 remains supportive while we await results of drug trials. More studies are needed to understand the incidence and outcomes of ARDS and critical illness from COVID-19, which will be important for critical care management and resource planning.
    MeSH term(s) Betacoronavirus/isolation & purification ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Critical Care ; Critical Illness ; Disease Progression ; Humans ; Male ; Middle Aged ; Patient Care Planning ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Respiratory Distress Syndrome/virology ; Risk Factors ; SARS-CoV-2 ; Severity of Illness Index
    Keywords covid19
    Language English
    Publishing date 2020-03-19
    Publishing country Singapore
    Document type Case Reports ; Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: [How to understand the histopathology of SARS and coronavirus disease-19 (COVID-19) associated with acute respiratory distress syndrome].

    Chen, J

    Zhonghua bing li xue za zhi = Chinese journal of pathology

    2020  Volume 49, Issue 4, Page(s) 289–290

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/pathology ; Humans ; Pandemics ; Pneumonia, Viral/pathology ; SARS-CoV-2 ; Severe Acute Respiratory Syndrome/pathology ; Severe Acute Respiratory Syndrome/virology
    Keywords covid19
    Language Chinese
    Publishing date 2020-03-22
    Publishing country China
    Document type Journal Article
    ZDB-ID 784533-9
    ISSN 0529-5807
    ISSN 0529-5807
    DOI 10.3760/cma.j.cn112151-20200309-00185
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Rapid Progression to Acute Respiratory Distress Syndrome: Review of Current Understanding of Critical Illness from COVID-19 Infection

    Goh, Ken J. / Choong, Mindy Cm / Cheong, Elizabeth Ht / Kalimuddin, Shirin / Duu Wen, Sewa / Phua, Ghee Chee / Chan, Kian Sing / Haja Mohideen, Salahudeen

    Annals of the Academy of Medicine, Singapore

    Abstract: ... rapidly worsening respiratory failure and acute respiratory distress syndrome (ARDS) that required ... The coronavirus disease 2019 (COVID-19) outbreak that started in Wuhan, Hubei province, China ... countries as of 7 March 2020 We report a case of COVID-19 infection in a 64-year-old man who developed ...

    Abstract The coronavirus disease 2019 (COVID-19) outbreak that started in Wuhan, Hubei province, China in December 2019 has now extended across the globe with >100,000 cases and 3,000 deaths reported in 93 countries as of 7 March 2020 We report a case of COVID-19 infection in a 64-year-old man who developed rapidly worsening respiratory failure and acute respiratory distress syndrome (ARDS) that required intubation As the clinical spectrum of COVID-19 ranges widely from mild illness to ARDS with a high risk of mortality, there is a need for more research to identify early markers of disease severity Current evidence suggests that patients with advanced age, pre-existing comorbidities or dyspnoea should be closely monitored, especially at 1-2 weeks after symptom onset It remains to be seen if laboratory findings such as lymphopenia or elevated lactate dehydrogenase may serve as early surrogates for critical illness or markers of disease recovery Management of ARDS in COVID-19 remains supportive while we await results of drug trials More studies are needed to understand the incidence and outcomes of ARDS and critical illness from COVID-19, which will be important for critical care management and resource planning
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #11670
    Database COVID19

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  10. Article ; Online: The Growing Understanding of the Pituitary Implication in the Pathogenesis of Long COVID-19 Syndrome: A Narrative Review.

    Taieb, Ach / Nassim, Ben Haj Slama / Asma, Gorchane / Jabeur, Methnani / Ghada, Saad / Asma, Ben Abdelkrim

    Advances in respiratory medicine

    2024  Volume 92, Issue 1, Page(s) 96–109

    Abstract: ... where individuals who have recovered from the acute phase of COVID-19 continue to experience a range of symptoms ... in Post COVID-19 Syndrome. The exact mechanisms of viral action on infected cells remain under discussion ... involvement of the pituitary gland in the persistence of Post COVID-19 Syndrome. ...

    Abstract Long COVID-19, also known as post-acute sequelae of SARS-CoV-2 infection, is a condition where individuals who have recovered from the acute phase of COVID-19 continue to experience a range of symptoms for weeks or even months afterward. While it was initially thought to primarily affect the respiratory system, it has become clear that Long COVID-19 can involve various organs and systems, including the endocrine system, which includes the pituitary gland. In the context of Long COVID-19, there is a growing understanding of the potential implications for the pituitary gland. The virus can directly affect the pituitary gland, leading to abnormalities in hormone production and regulation. This can result in symptoms such as fatigue, changes in appetite, and mood disturbances. Long COVID-19, the persistent and often debilitating condition following acute COVID-19 infection, may be explained by deficiencies in ACTH and Growth hormone production from the pituitary gland. Corticotropin insufficiency can result in the dysregulation of the body's stress response and can lead to prolonged feelings of stress, fatigue, and mood disturbances in Long COVID-19 patients. Simultaneously, somatotropin insufficiency can affect growth, muscle function, and energy metabolism, potentially causing symptoms such as muscle weakness, exercise intolerance, and changes in body composition. Recently, some authors have suggested the involvement of the pituitary gland in Post COVID-19 Syndrome. The exact mechanisms of viral action on infected cells remain under discussion, but inflammatory and autoimmune mechanisms are primarily implicated. The aim of our study will be to review the main pituitary complications following COVID-19 infection. Moreover, we will explain the possible involvement of the pituitary gland in the persistence of Post COVID-19 Syndrome.
    MeSH term(s) Humans ; Post-Acute COVID-19 Syndrome ; COVID-19 ; SARS-CoV-2 ; Pituitary Gland ; Fatigue/etiology
    Language English
    Publishing date 2024-02-14
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2893877-X
    ISSN 2543-6031 ; 2451-4934
    ISSN (online) 2543-6031
    ISSN 2451-4934
    DOI 10.3390/arm92010013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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