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Article: Does reactivation of cytomegalovirus contribute to severe COVID-19 disease?

Söderberg-Nauclér, Cecilia

Immunity & ageing : I & A

2021  Volume 18, Issue 1, Page(s) 12

Abstract: ... mortality rate. The risk of severe COVID-19 is highest among those who are over 70 years of age. Why severe ... COVID-19 develops in some people but not others is not understood. Could some cases involve reactivation ... of latent cytomegalovirus (CMV)? ...

Abstract The majority of people infected with SARS-CoV-2 are asymptomatic or have mild to moderate symptoms. However, for unknown reasons, about 15 % have severe pneumonia requiring hospital care and oxygen support, and about 5 % develop acute respiratory distress syndrome, septic shock, and multiorgan failure that result in a high mortality rate. The risk of severe COVID-19 is highest among those who are over 70 years of age. Why severe COVID-19 develops in some people but not others is not understood. Could some cases involve reactivation of latent cytomegalovirus (CMV)?
Language English
Publishing date 2021-03-12
Publishing country England
Document type Letter
ISSN 1742-4933
ISSN 1742-4933
DOI 10.1186/s12979-021-00218-z
Database MEDical Literature Analysis and Retrieval System OnLINE

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