Article ; Online: Pragmatic clinic randomized trial to improve chronic kidney disease care: Design and adaptation due to COVID disruptions.
2021 Volume 109, Page(s) 106501
Abstract: Background: We describe a clinic-randomized trial to improve chronic kidney disease (CKD) care ... we encountered due to COVID-19 care disruption.: Methods/design: Primary care clinics (N = 32) were randomized ... trial of web-based EHR-integrated CKD-CDS and modifications necessary mid-study to complete the study ...
| Abstract | Background: We describe a clinic-randomized trial to improve chronic kidney disease (CKD) care through a CKD-clinical decision support (CKD-CDS) intervention in primary care clinics and the challenges we encountered due to COVID-19 care disruption. Methods/design: Primary care clinics (N = 32) were randomized to usual care (UC) or to CKD-CDS. Between April 17, 2019 and March 14, 2020, more than 7000 patients had accrued for analysis by meeting study-eligibility criteria at an index office visit: age 18-75, laboratory criteria for stage 3 or 4 CKD (eGFR 15-59 mL/min/1.73 m Discussion: We describe a NIH-funded pragmatic trial of web-based EHR-integrated CKD-CDS and modifications necessary mid-study to complete the study as intended in the face of COVID-19 pandemic challenges. |
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| MeSH term(s) | Adolescent ; Adult ; Aged ; Angiotensin Receptor Antagonists/therapeutic use ; Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; COVID-19 ; Humans ; Middle Aged ; Pandemics ; Primary Health Care ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/therapy ; SARS-CoV-2 ; Young Adult | |||||
| Chemical Substances | Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors | |||||
| Language | English | |||||
| Publishing date | 2021-07-13 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural | |||||
| ZDB-ID | 2182176-8 | |||||
| ISSN | 1559-2030 ; 1551-7144 | |||||
| ISSN (online) | 1559-2030 | |||||
| ISSN | 1551-7144 | |||||
| DOI | 10.1016/j.cct.2021.106501 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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