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Article ; Online: Making US poison centers a part of the solution to the COVID-19 pandemic.

Spyker, Daniel A / Bronstein, Alvin C / Weber, Julie A

Clinical toxicology (Philadelphia, Pa.)

2021  Volume 60, Issue 1, Page(s) 102–114

Abstract: ... 13-Feb-2020 through 15-Apr-2021 National Poison Data System (NPDS) COVID-19 records for changes over ... time. We examined NPDS cases and VAERS COVID-19 vaccine reports 1-Nov-2020 through 2-Apr-2021 ... 052,174 COVID-19 contacts; maximum (peak) contacts/day (12,163) on 16-Mar-2020. As of 5-Apr-2021 ...

Abstract Objectives: Our six goals are: 1) describe the relationship between the
Methods: We reviewed 13-Feb-2020 through 15-Apr-2021 National Poison Data System (NPDS) COVID-19 records for changes over time. We examined NPDS cases and VAERS COVID-19 vaccine reports 1-Nov-2020 through 2-Apr-2021 for vaccine manufacturer, patient characteristics, state, and clinical effects.
Results: PCs reported 1,052,174 COVID-19 contacts; maximum (peak) contacts/day (12,163) on 16-Mar-2020. As of 5-Apr-2021 the US reported >167 million administrations of COVID-19 vaccines (Pfizer-BioNTech, Moderna or Janssen). US PCs reported 162,052 COVID-19 vaccine contacts. Most (61.1%) were medical information calls, 34.9% were drug information, and 2.58% were exposures. Over the same period VAERS reported 49,078 COVID-19 vaccine cases reporting 226,205 symptoms - headache most frequent, ranging from 20% to 40% across the 3 vaccines.
Conclusions and recommendations: Although differences exist between the intent and content of the 2 data sets, NPDS volume is compelling. The PC nationwide 800 number facilitates data collection and suggests comingling the 2 data streams has merit. PC professionals received tens of thousands of calls and can: 1) support fact-based vaccine information; 2) contribute vaccine AE follow-up information: 3) advocate for best-case coding and reporting, especially for vaccine adverse experiences.
MeSH term(s) Adverse Drug Reaction Reporting Systems ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Humans ; Pandemics ; Poison Control Centers ; United States
Chemical Substances COVID-19 Vaccines
Language English
Publishing date 2021-08-27
Publishing country England
Document type Journal Article
ZDB-ID 204476-6
ISSN 1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
ISSN (online) 1556-9519
ISSN 0009-9309 ; 0731-3810 ; 1556-3650
DOI 10.1080/15563650.2021.1933510
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