Article ; Online: Stopping lopinavir/ritonavir in COVID-19 patients: duration of the drug interacting effect.
The Journal of antimicrobial chemotherapy
2020 Volume 75, Issue 10, Page(s) 3084–3086
MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/drug therapy ; Coronavirus Infections/metabolism ; Cytochrome P-450 CYP3A Inhibitors/administration & dosage ; Cytochrome P-450 CYP3A Inhibitors/metabolism ; Drug Interactions/physiology ; Drug Therapy, Combination ; Female ; Humans ; Lopinavir/administration & dosage ; Lopinavir/metabolism ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/drug therapy ; Pneumonia, Viral/metabolism ; Ritonavir/administration & dosage ; Ritonavir/metabolism ; SARS-CoV-2 ; Time Factors ; Withholding Treatment/trends ; Young Adult |
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Chemical Substances | Cytochrome P-450 CYP3A Inhibitors ; Lopinavir (2494G1JF75) ; Ritonavir (O3J8G9O825) |
Keywords | covid19 |
Language | English |
Publishing date | 2020-06-01 |
Publishing country | England |
Document type | Letter ; Research Support, Non-U.S. Gov't |
ZDB-ID | 191709-2 |
ISSN | 1460-2091 ; 0305-7453 |
ISSN (online) | 1460-2091 |
ISSN | 0305-7453 |
DOI | 10.1093/jac/dkaa253 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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