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Article: Pseudocyesis: psychologic and neuroendocrine interrelationships.

Starkman, M N / Marshall, J C / La Ferla, J / Kelch, R P

Psychosomatic medicine

1985  Volume 47, Issue 1, Page(s) 46–57

Abstract: ... neuroendocrine abnormalities in pseudocyesis. We have studied two patients using a multimodal investigatory ... single neuroendocrine profile is common to all patients with pseudocyesis. ... There is a paucity of information concerning the interrelationship of psychiatric and ...

Abstract There is a paucity of information concerning the interrelationship of psychiatric and neuroendocrine abnormalities in pseudocyesis. We have studied two patients using a multimodal investigatory approach, with particular attention to the association of depression and alterations in endocrine secretory patterns. Both patients had abnormal growth hormone secretory patterns, as demonstrated by lack of sleep-associated peaks and the absence of a response to L-dopa administration. Both patients had elevated testosterone and estradiol levels and normal prolactin levels. Only the patient who met DSM III criteria for a major depressive episode had abnormally elevated luteinizing hormone (LH) levels and large LH pulse amplitudes. These findings, together with a review of cases reported in the literature, suggest that no single neuroendocrine profile is common to all patients with pseudocyesis.
MeSH term(s) Adult ; Depressive Disorder/complications ; Estradiol/blood ; Female ; Grief ; Growth Hormone/blood ; Histrionic Personality Disorder/complications ; Hormones/blood ; Humans ; Luteinizing Hormone/blood ; Pseudopregnancy/blood ; Pseudopregnancy/etiology ; Pseudopregnancy/psychology ; Testosterone/blood
Chemical Substances Hormones ; Testosterone (3XMK78S47O) ; Estradiol (4TI98Z838E) ; Luteinizing Hormone (9002-67-9) ; Growth Hormone (9002-72-6)
Language English
Publishing date 1985-01
Publishing country United States
Document type Case Reports ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID 3469-1
ISSN 1534-7796 ; 0033-3174
ISSN (online) 1534-7796
ISSN 0033-3174
DOI 10.1097/00006842-198501000-00005
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