Article ; Online: Rates of COVID-19-Related Outcomes in Cancer Compared With Noncancer Patients.
JNCI cancer spectrum
2021 Volume 5, Issue 1, Page(s) Pkaa120
Abstract: ... disease 2019 (COVID-19) infection. Increased COVID-19 morbidity and mortality in cancer patients may be ... to the cancer itself. Most studies to date have focused on hospitalized patients with severe COVID-19, thereby ... We compared outcomes of SARS-CoV-2 infection in 323 patients enrolled in a population-based study ...
| Abstract | Cancer patients are a vulnerable population postulated to be at higher risk for severe coronavirus disease 2019 (COVID-19) infection. Increased COVID-19 morbidity and mortality in cancer patients may be attributable to age, comorbidities, smoking, health care exposure, and cancer treatments, and partially to the cancer itself. Most studies to date have focused on hospitalized patients with severe COVID-19, thereby limiting the generalizability and interpretability of the association between cancer and COVID-19 severity. We compared outcomes of SARS-CoV-2 infection in 323 patients enrolled in a population-based study before the pandemic (n = 67 cancer patients; n = 256 noncancer patients). After adjusting for demographics, smoking status, and comorbidities, a diagnosis of cancer was independently associated with higher odds of hospitalization (odds ratio = 2.16, 95% confidence interval = 1.12 to 4.18) and 30-day mortality (odds ratio = 5.67, 95% confidence interval = 1.49 to 21.59). These associations were primarily driven by patients with active cancer. These results emphasize the critical importance of preventing SARS-CoV-2 exposure and mitigating infection in cancer patients. |
|---|---|
| MeSH term(s) | Adult ; Aged ; COVID-19/complications ; COVID-19/epidemiology ; COVID-19/virology ; Female ; Hospitalization/statistics & numerical data ; Humans ; Intensive Care Units/statistics & numerical data ; Male ; Middle Aged ; Neoplasms/complications ; Neoplasms/mortality ; Neoplasms/therapy ; Odds Ratio ; Outcome Assessment, Health Care ; Pandemics ; Risk Factors ; SARS-CoV-2/physiology ; Survival Rate |
| Language | English |
| Publishing date | 2021-01-21 |
| Publishing country | England |
| Document type | Comparative Study ; Journal Article ; Research Support, N.I.H., Extramural |
| ISSN | 2515-5091 |
| ISSN (online) | 2515-5091 |
| DOI | 10.1093/jncics/pkaa120 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.
Inter-library loan at ZB MED
Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.