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  1. Article ; Online: Recognition, diagnosis, and early management of sepsis: NICE guideline.

    Tavaré, Alison / O'Flynn, Norma

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2017  Volume 67, Issue 657, Page(s) 185–186

    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Checklist ; Early Diagnosis ; Guideline Adherence ; Humans ; Practice Guidelines as Topic ; Primary Health Care ; Risk Factors ; Sepsis/diagnosis ; United Kingdom
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2017
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp17X690401
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Book ; Online: Sepsis

    National Guideline Centre (Great Britain), ; National Institute for Health and Care Excellence (Great Britain), ; Royal College of Physicians of London,

    recognition, assessment and early management : final version

    (NICE guideline ; 51)

    2016  

    Abstract: ... avoidable deaths, people with sepsis need to be recognised early and treatment initiated. This guideline ... for anyone presenting with a possible infection. Detailed guidelines exist for the management of sepsis in adult and ... with someone of any age with chest pain, this guideline aims to make "could this be sepsis?" the first consideration ...

    Author's details developed by the National Guideline Centre, hosted by the Royal College of Physicians
    Series title NICE guideline ; 51
    Abstract Sepsis is a clinical syndrome caused by the body's immune and coagulation systems being switched on by an infection. Sepsis with shock is a life-threatening condition that is characterised by low blood pressure despite adequate fluid replacement, and organ dysfunction or failure. Sepsis is an important cause of death in people of all ages. Both a UK Parliamentary and Health Service Ombudsman enquiry (2013) and UK National Confidential Enquiry into Patient Outcome and Death (NCEPOD, 2015) have recently highlighted sepsis as being a leading cause of avoidable death that kills more people than breast, bowel and prostate cancer combined. Clinicians and healthcare professionals of all kinds, at all levels of seniority and in all clinical settings often find sepsis difficult to diagnose with certainty. Although people with sepsis may have a history of infection, fever is not present in all cases. The signs and symptoms of sepsis are usually very non-specific and can be missed if clinicians do not think "could this be sepsis?". In the same way that healthcare professionals consider "could this pain be cardiac in origin?" when presented with someone of any age with chest pain, this guideline aims to make "could this be sepsis?" the first consideration for anyone presenting with a possible infection. Detailed guidelines exist for the management of sepsis in adult and paediatric intensive care units, and by intensive care clinicians called to other settings. To reduce avoidable deaths, people with sepsis need to be recognised early and treatment initiated. This guideline aims to ensure healthcare systems in all clinical settings consider sepsis as an immediate life-threatening condition that should be recognised and treated as an emergency. The guideline outlines the immediate actions required for those with suspicion of sepsis and who are at highest risk of morbidity and mortality from sepsis. It provides a framework for risk assessment, treatment and follow-up or "safety-netting" of people not requiring immediate resuscitation.
    MeSH term(s) Sepsis/diagnosis ; Sepsis/therapy ; Risk Assessment ; Evidence-Based Medicine
    Keywords United Kingdom
    Language English
    Size 1 online resource (1 PDF file (583 pages)) :, illustrations.
    Document type Book ; Online
    ISBN 9781473119987 ; 1473119987
    Database Catalogue of the US National Library of Medicine (NLM)

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