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  1. Article ; Online: Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.

    Tejada Cifuentes, Francisco / Lloret Callejo, Ángeles / Tirado Peláez, María José / Rubio Pulido, Olga / Ruiz-Morote Aragón, Marta / Fernández Urrusuno, Rocío / Muñoz Carreras, María Isabel / Méndez Esteban, María Isabel / Maestre Sánchez, Victoria / García Bonilla, Antonio / Paredero Dominguez, José Manuel / Arroyo Pineda, Virginia / Marco Tejón, Esther / Romero Candel, Gregorio / Fernández Marchante, Ana Isabel / Marco Del Rio, José / Ortiz Martín, Teresa / López Sánchez, Piedad

    Medicina clinica (English ed.)

    2021  Volume 156, Issue 4, Page(s) 166–171

    Abstract: ... relationship between chronic use of hydroxychloroquine and the incidence of Covid-19. ... Objective: To analyze the incidence of Covid-19 in patients who are chronic users ... 4,45%) patients had Covid-19 infection, of which 12 (7.1 %) died and 32 (18.9%) required hospital ...

    Abstract Objective: To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine.
    Patients and methods: Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded.
    Results: 169 (4,45%) patients had Covid-19 infection, of which 12 (7.1 %) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (
    Conclusion: There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.
    Language English
    Publishing date 2021-01-23
    Publishing country Spain
    Document type Journal Article
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.10.012
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Incidencia de la COVID-19 en pacientes en tratamiento crónico con hidroxicloroquina.

    Tejada Cifuentes, Francisco / Lloret Callejo, Ángeles / Tirado Peláez, María José / Rubio Pulido, Olga / Ruiz-Morote Aragón, Marta / Fernández Urrusuno, Rocío / Muñoz Carreras, María Isabel / Méndez Esteban, María Isabel / Maestre Sánchez, Victoria / García Bonilla, Antonio / Paredero Dominguez, José Manuel / Arroyo Pineda, Virginia / Marco Tejón, Esther / Romero Candel, Gregorio / Fernández Marchante, Ana Isabel / Marco Del Rio, José / Ortiz Martín, Teresa / López Sánchez, Piedad

    Medicina clinica

    2020  Volume 156, Issue 4, Page(s) 166–171

    Abstract: ... Conclusion: There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19. ... Objective: To analyze the incidence of Covid-19 in patients who are chronic users ... 4,45%) patients had Covid-19 infection, of which 12 (7.1%) died and 32 (18.9%) required hospital ...

    Title translation Incidence of COVID-19 in patients under chronic treatment with hydroxychloroquine.
    Abstract Objective: To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine.
    Patients and methods: Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded.
    Results: 169 (4,45%) patients had Covid-19 infection, of which 12 (7.1%) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (P<.05). Maculopathy appears in 5.3% of patients and is significantly related to the dose of hydroxychloroquine consumed (P<.05).
    Conclusion: There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Antirheumatic Agents/therapeutic use ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19 Testing ; Chronic Disease ; Cross-Sectional Studies ; Female ; Humans ; Hydroxychloroquine/therapeutic use ; Incidence ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/drug therapy ; Male ; Middle Aged ; Prognosis ; Protective Factors ; Retrospective Studies ; Risk Factors ; Spain/epidemiology
    Chemical Substances Antirheumatic Agents ; Hydroxychloroquine (4QWG6N8QKH)
    Language Spanish
    Publishing date 2020-11-06
    Publishing country Spain
    Document type Journal Article ; Multicenter Study ; Observational Study
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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