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Article: Nonvalue of the initial microbiological studies in the management of nonsevere community-acquired pneumonia.

Theerthakarai, R / El-Halees, W / Ismail, M / Solis, R A / Khan, M A

Chest

2001  Volume 119, Issue 1, Page(s) 181–184

Abstract: ... cultures, have no value in the management of nonsevere CAP without comorbid factors. ... Study objective: To assess the value of the initial microbiological studies (MBS), consisting ... acquired pneumonia (CAP) without comorbidity.: Design: A prospective study of 74 adult patients ...

Abstract Study objective: To assess the value of the initial microbiological studies (MBS), consisting of sputum Gram's stains, sputum cultures, and blood cultures, in the etiologic diagnosis of community-acquired pneumonia (CAP) without comorbidity.
Design: A prospective study of 74 adult patients hospitalized with nonsevere CAP empirically treated according to the American Thoracic Society guidelines (ATS-GL) and evaluated with Gram's stains and cultures of valid sputum specimens and blood cultures.
Setting: University-affiliated community hospital.
Results: Gram's stain of a valid sputum specimen failed to identify the etiologic agent in all patients. Sputum cultures identified pathogens in only four patients (5%). The results of all blood cultures were negative. All patients responded to the initial empiric antibiotic coverage selected according to the ATS-GL, and the results of the initial MBS had no clinical impact.
Conclusion: The initial MBS, such as sputum Gram's stains, sputum cultures, and blood cultures, have no value in the management of nonsevere CAP without comorbid factors.
MeSH term(s) Adult ; Bacteriological Techniques ; Community-Acquired Infections/diagnosis ; Community-Acquired Infections/microbiology ; Female ; Gentian Violet ; Humans ; Male ; Middle Aged ; Phenazines ; Pneumonia, Bacterial/diagnosis ; Pneumonia, Bacterial/microbiology ; Predictive Value of Tests ; Prospective Studies ; Sputum/microbiology
Chemical Substances Gram's stain ; Phenazines ; Gentian Violet (J4Z741D6O5)
Language English
Publishing date 2001-01
Publishing country United States
Document type Journal Article
ZDB-ID 1032552-9
ISSN 1931-3543 ; 0012-3692
ISSN (online) 1931-3543
ISSN 0012-3692
DOI 10.1378/chest.119.1.181
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