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Article ; Online: Omeprazole suppressed plasma magnesium level and duodenal magnesium absorption in male Sprague-Dawley rats.

Thongon, Narongrit / Penguy, Jirawat / Kulwong, Sasikan / Khongmueang, Kanyanat / Thongma, Matthana

Pflugers Archiv : European journal of physiology

2016  Volume 468, Issue 11-12, Page(s) 1809–1821

Abstract: Hypomagnesemia is the most concerned side effect of proton pump inhibitors (PPIs) in chronic users. However, the mechanism of PPIs-induced systemic ... ...

Abstract Hypomagnesemia is the most concerned side effect of proton pump inhibitors (PPIs) in chronic users. However, the mechanism of PPIs-induced systemic Mg
MeSH term(s) Animals ; Anti-Ulcer Agents/adverse effects ; Anti-Ulcer Agents/pharmacology ; Cation Transport Proteins/metabolism ; Claudins/metabolism ; Duodenum/drug effects ; Duodenum/metabolism ; Intestinal Absorption/drug effects ; Magnesium/blood ; Magnesium/metabolism ; Magnesium Deficiency/etiology ; Male ; Omeprazole/adverse effects ; Omeprazole/pharmacology ; Rats ; Rats, Sprague-Dawley ; TRPM Cation Channels/metabolism
Chemical Substances Anti-Ulcer Agents ; Cation Transport Proteins ; Claudins ; Cnnm4 protein, rat ; TRPM Cation Channels ; TRPM6 protein, rat ; Magnesium (I38ZP9992A) ; Omeprazole (KG60484QX9)
Language English
Publishing date 2016
Publishing country Germany
Document type Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 6380-0
ISSN 1432-2013 ; 0031-6768
ISSN (online) 1432-2013
ISSN 0031-6768
DOI 10.1007/s00424-016-1905-7
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