LIVIVO - Search results -

Search results

Result 1 - 10 of total 505

Search options

Article ; Online: Long-term respiratory consequences of COVID-19 related pneumonia: a cohort study.

Eizaguirre, Saioa / Sabater, Gladis / Belda, Sònia / Calderón, Juan Carlos / Pineda, Victor / Comas-Cufí, Marc / Bonnin, Marc / Orriols, Ramon

BMC pulmonary medicine

2023 Volume 23, Issue 1, Page(s) 439

Abstract: ... in COVID-19 patients with severe pneumonia requiring non-invasive respiratory support therapies.: Methods ... of patients presenting dyspnoea ≥ 2 decreased (19% vs 7%), the quality-of-life total score improved (22.8% vs ... Background: Our aims were to describe respiratory sequelae up to 12 months after discharge ...

Abstract	Background: Our aims were to describe respiratory sequelae up to 12 months after discharge in COVID-19 patients with severe pneumonia requiring non-invasive respiratory support therapies. Methods: This study was undertaken at University Hospital Doctor Josep Trueta (Girona, Spain) between March 2020 and June 2020. Three months after discharge, we evaluated their dyspnoea and performed Saint George's respiratory questionnaire, pulmonary function tests, blood test, 6-min walking test, and a high-resolution CT (HRCT). At the six and 12-month follow-up, we repeated all tests except for pulmonary function, 6-min walking test, and HRCT, which were performed only if abnormal findings had been previously detected. Results: Out of the 94 patients recruited, 73% were male, the median age was 62.9 years old, and most were non-smokers (58%). When comparing data three and 12 months after discharge, the percentage of patients presenting dyspnoea ≥ 2 decreased (19% vs 7%), the quality-of-life total score improved (22.8% vs 18.9%; p = 0.019), there were less abnormal results in the pulmonary function tests (47% vs 23%), the 6-min walking test distance was enhanced (368.3 m vs 390.7 m, p = 0.020), ground glass opacities findings waned (51.6% vs 11.5%), and traction bronchiectasis increased (5.6% vs 15.9%). Only age showed significant differences between patients with and without pulmonary fibrotic-like changes. Conclusion: Most patients improved their clinical condition, pulmonary function, exercise capacity and quality of life one year after discharge. Nonetheless, pulmonary fibrotic-like changes were observed during the follow-ups.
MeSH term(s)	Humans ; Male ; Middle Aged ; Female ; COVID-19/complications ; Cohort Studies ; Quality of Life ; Lung/diagnostic imaging ; Pulmonary Fibrosis ; Dyspnea/etiology
Language	English
Publishing date	2023-11-11
Publishing country	England
Document type	Journal Article
ZDB-ID	2059871-3
ISSN	1471-2466 ; 1471-2466
ISSN (online)	1471-2466
ISSN	1471-2466
DOI	10.1186/s12890-023-02627-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: COVID-19: long-term respiratory consequences.

Toufen Junior, Carlos / Pêgo-Fernandes, Paulo Manuel

Sao Paulo medical journal = Revista paulista de medicina

2021 Volume 139, Issue 5, Page(s) 421–423

MeSH term(s)	COVID-19 ; Humans ; SARS-CoV-2
Language	English
Publishing date	2021-07-14
Publishing country	Brazil
Document type	Editorial
ZDB-ID	1203171-9
ISSN	1806-9460 ; 1516-3180 ; 0035-0362
ISSN (online)	1806-9460
ISSN	1516-3180 ; 0035-0362
DOI	10.1590/1516-3180.2021.139526052021
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 184: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Consideration of prevention and management of long-term consequences of post-acute respiratory distress syndrome in patients with COVID-19.

Candan, Sevim Acaroz / Elibol, Nuray / Abdullahi, Auwal

Physiotherapy theory and practice

2020 Volume 36, Issue 6, Page(s) 663–668

Abstract: ... as the short-term, consequences of acute respiratory distress syndrome (ARDS) associated with COVID-19 ... This manuscript provides support for physical therapists to focus on the long-term, as well ... However, in recent years, research has focused on poor long-term functional outcomes in patients with ARDS, often ...

Abstract	This manuscript provides support for physical therapists to focus on the long-term, as well as the short-term, consequences of acute respiratory distress syndrome (ARDS) associated with COVID-19. Since late November 2019, COVID-19 has become a global health pandemic and threat. Although most people have no or mild symptoms, COVID-19 spreads aggressively and can lead to ARDS rapidly in a proportion of individuals. The evidence supports that gas exchange and countering the negative effects of bed rest and immobility are priorities in severely affected patients admitted to the intensive care unit (ICU). However, in recent years, research has focused on poor long-term functional outcomes in patients with ARDS, often associated with ICU-acquired weakness, deconditioning, and myopathies and neuropathies. In addition to physical therapists providing respiratory support in the ICU, the literature unequivocally supports the view that early intervention for ICU management of patients with ARDS secondary to COVID-19 needs to focus on reducing contributors to impaired long-term function, with direct attention paid to preventing or managing ICU-acquired weakness, deconditioning, and myopathies and neuropathies, in conjunction with respiratory care.
MeSH term(s)	Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/therapy ; Critical Care ; Humans ; Muscular Diseases/prevention & control ; Muscular Diseases/virology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/therapy ; Respiratory Distress Syndrome/prevention & control ; Respiratory Distress Syndrome/virology ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-05-18
Publishing country	England
Document type	Journal Article
ZDB-ID	1045333-7
ISSN	1532-5040 ; 0959-3985
ISSN (online)	1532-5040
ISSN	0959-3985
DOI	10.1080/09593985.2020.1766181
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2190: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Consideration of prevention and management of long-term consequences of post-acute respiratory distress syndrome in patients with COVID-19

Candan, Sevim Acaroz / Elibol, Nuray / Abdullahi, Auwal

Physiotherapy Theory and Practice

2020 Volume 36, Issue 6, Page(s) 663–668

Keywords	Physical Therapy, Sports Therapy and Rehabilitation ; covid19
Language	English
Publisher	Informa UK Limited
Publishing country	uk
Document type	Article ; Online
ZDB-ID	1045333-7
ISSN	1532-5040 ; 0959-3985
ISSN (online)	1532-5040
ISSN	0959-3985
DOI	10.1080/09593985.2020.1766181
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 2190: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Consideration of prevention and management of long-term consequences of post-acute respiratory distress syndrome in patients with COVID-19

Candan, Sevim Acaroz / Elibol, Nuray / Abdullahi, Auwal

Physiother Theory Pract

Abstract	This manuscript provides support for physical therapists to focus on the long-term, as well as the short-term, consequences of acute respiratory distress syndrome (ARDS) associated with COVID-19. Since late November 2019, COVID-19 has become a global health pandemic and threat. Although most people have no or mild symptoms, COVID-19 spreads aggressively and can lead to ARDS rapidly in a proportion of individuals. The evidence supports that gas exchange and countering the negative effects of bed rest and immobility are priorities in severely affected patients admitted to the intensive care unit (ICU). However, in recent years, research has focused on poor long-term functional outcomes in patients with ARDS, often associated with ICU-acquired weakness, deconditioning, and myopathies and neuropathies. In addition to physical therapists providing respiratory support in the ICU, the literature unequivocally supports the view that early intervention for ICU management of patients with ARDS secondary to COVID-19 needs to focus on reducing contributors to impaired long-term function, with direct attention paid to preventing or managing ICU-acquired weakness, deconditioning, and myopathies and neuropathies, in conjunction with respiratory care.
Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #291096
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: COVID, complement, and the brain.

Vlaicu, Sonia I / Tatomir, Alexandru / Cuevas, Jacob / Rus, Violeta / Rus, Horea

Frontiers in immunology

2023 Volume 14, Page(s) 1216457

Abstract: ... may contribute to several COVID-19 sequelae, including cognitive dysfunction (termed "long COVID ... The brains of COVID-19 patients are affected by the SARS-CoV-2 virus, and these effects ... cognitive decline. COVID-19 can directly infect endothelial cells of the brain, potentially promoting clot ...

Abstract	The brains of COVID-19 patients are affected by the SARS-CoV-2 virus, and these effects may contribute to several COVID-19 sequelae, including cognitive dysfunction (termed "long COVID" by some researchers). Recent advances concerning the role of neuroinflammation and the consequences for brain function are reviewed in this manuscript. Studies have shown that respiratory SARS-CoV-2 infection in mice and humans is associated with selective microglial reactivity in the white matter, persistently impaired hippocampal neurogenesis, a decrease in the number of oligodendrocytes, and myelin loss. Brain MRI studies have revealed a greater reduction in grey matter thickness in the orbitofrontal cortex and parahippocampal gyrus, associated with a greater reduction in global brain size, in those with SARS-CoV-2 and a greater cognitive decline. COVID-19 can directly infect endothelial cells of the brain, potentially promoting clot formation and stroke; complement C3 seems to play a major role in this process. As compared to controls, the brain tissue of patients who died from COVID-19 have shown a significant increase in the extravasation of fibrinogen, indicating leakage in the blood-brain barrier; furthermore, recent studies have documented the presence of IgG, IgM, C1q, C4d, and C5b-9 deposits in the brain tissue of COVID-19 patients. These data suggest an activation of the classical complement pathway and an immune-mediated injury to the endothelial cells. These findings implicate both the classical and alternative complement pathways, and they indicate that C3b and the C5b-9 terminal complement complex (membrane attack complex, MAC) are acting in concert with neuroinflammatory and immune factors to contribute to the neurological sequelae seen in patients with COVID.
MeSH term(s)	Humans ; Mice ; Animals ; Complement Membrane Attack Complex/metabolism ; Endothelial Cells/metabolism ; SARS-CoV-2/metabolism ; COVID-19 ; Brain/metabolism
Chemical Substances	Complement Membrane Attack Complex
Language	English
Publishing date	2023-07-18
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1216457
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Long COVID

Mohammed Masood / Sai Sundeep Chodisetti / Ahmed S BaHammam

Journal of Nature and Science of Medicine, Vol 6, Iss 1, Pp 3-

The long-term consequences of COVID-19 and the proposed pathophysiological mechanisms

2023 Volume 11

Abstract: ... till now. After recovery from COVID-19, some patients develop long-term sequelae called long COVID (LC). LC ... The new devastating pandemic coronavirus disease 2019 (COVID-19) caused by the novel coronavirus ... understanding of the pathophysiology and successful treatment of acute COVID-19, and we see more survivors and ...

Abstract	The new devastating pandemic coronavirus disease 2019 (COVID-19) caused by the novel coronavirus severe acute respiratory syndrome (SARS-CoV-2) has been related to approximately 600 million cases and more than six million deaths till now. After recovery from COVID-19, some patients develop long-term sequelae called long COVID (LC). LC cases have been reported with multi-system involvement, with the most common being neuro-psychiatric, cardiorespiratory, hematological, and gastrointestinal systems highlighting the need for multidisciplinary team involvement and treatment. Since we are more than two and half years into this pandemic, we have more understanding of the pathophysiology and successful treatment of acute COVID-19, and we see more survivors and, subsequently, individuals with LC. However, the pathogenic mechanisms leading to LC are not clear till now. This review describes the potential pathogenic mechanisms leading to LC and common clinical manifestations reported from current evidence.
Keywords	coronavirus disease 2019 ; immune response ; postacute coronavirus disease 2019 syndrome ; postacute sequelae of coronavirus disease 2019 ; postcoronavirus disease 2019 condition ; severe acute respiratory syndrome coronavirus 2 ; Medicine ; R ; Public aspects of medicine ; RA1-1270
Subject code	610
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Men, testosterone and Covid-19.

Groti Antonic, Kristina / Antonic, Blaz / Caliber, Monica / Dhindsa, Sandeep

Clinical endocrinology

2023 Volume 100, Issue 1, Page(s) 56–65

Abstract: ... consequences of Covid-19 on male reproductive health are reviewed. SARS-CoV-2 virus is known to infiltrate ... studies that have evaluated the role of androgens in SARS-CoV-2 infection and illness. Finally, long-term ... Men have more severe Coronavirus disease 2019 (Covid-19) outcomes and higher mortality rates ...

Abstract	Men have more severe Coronavirus disease 2019 (Covid-19) outcomes and higher mortality rates than women, and it was suggested that testosterone levels might promote severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and Covid-19 severity. However, clinical studies have not supported this theory. Studies have consistently shown that serum testosterone concentrations during acute Covid-19 in men are inversely proportional to the inflammatory cytokines and severity of illness. It is likely that lower testosterone concentrations in this setting are a result of acute Covid-19 illness on the hypothalamic-pituitary-testicular axis. Clinical trials that attempted to lower testosterone concentrations further or block androgen signaling acutely during Covid-19 in men did not result in improved Covid-19 outcomes. Additionally, pre-existing male hypogonadism, diagnosed before Covid-19 pandemic, was found to be a risk factor for hospitalization from Covid-19. In this review, we also discuss the preclinical and mechanistic studies that have evaluated the role of androgens in SARS-CoV-2 infection and illness. Finally, long-term consequences of Covid-19 on male reproductive health are reviewed. SARS-CoV-2 virus is known to infiltrate testis and induce orchitis in men, but it is unclear if Covid-19 leads to an increase in incidence of male hypogonadism.
MeSH term(s)	Humans ; Male ; Female ; Testosterone ; COVID-19/complications ; SARS-CoV-2 ; Pandemics ; Androgens/therapeutic use ; Hypogonadism/drug therapy
Chemical Substances	Testosterone (3XMK78S47O) ; Androgens
Language	English
Publishing date	2023-07-27
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	121745-8
ISSN	1365-2265 ; 0300-0664
ISSN (online)	1365-2265
ISSN	0300-0664
DOI	10.1111/cen.14952
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 814: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Post-COVID-19 Condition.

Nalbandian, Ani / Desai, Amar D / Wan, Elaine Y

Annual review of medicine

2022 Volume 74, Page(s) 55–64

Abstract: ... of this entity and its long-term health consequences. ... An estimated 10-15% of those infected with SARS-CoV-2 may have post-COVID-19 condition. Common ... indicate post-COVID-19 condition may occur independent of acuity of initial infection, hospitalization ...

Abstract	An estimated 10-15% of those infected with SARS-CoV-2 may have post-COVID-19 condition. Common lingering signs and symptoms include shortness of breath, fatigue, high heart rate, and memory and cognitive dysfunction even several months after infection, often impacting survivors' quality of life. The prevalence and duration of individual symptoms remain difficult to ascertain due to the lack of standardized research methods across various studies and limited patient follow-up in clinical studies. Nonetheless, data indicate post-COVID-19 condition may occur independent of acuity of initial infection, hospitalization status, age, or pre-existing comorbidities. Risk factors may include female sex and underlying respiratory or psychiatric disease. Supportive therapies to mitigate symptoms remain the mainstay of treatment. Reassuringly, most patients experience a reduction in symptoms by 1 year. The use of a universal case definition and shared research methods will allow for further clarity regarding the pervasiveness of this entity and its long-term health consequences.
MeSH term(s)	Humans ; Female ; COVID-19 ; Quality of Life ; SARS-CoV-2 ; Cognitive Dysfunction/epidemiology ; Cognitive Dysfunction/etiology ; Dyspnea
Language	English
Publishing date	2022-08-01
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	207930-6
ISSN	1545-326X ; 0066-4219
ISSN (online)	1545-326X
ISSN	0066-4219
DOI	10.1146/annurev-med-043021-030635
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ua VI Zs.321: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Evaluation of post-acute-COVID-19, and long-COVID symptoms with a questionnaire: Within one year, a longitudinal study.

Emiroglu, Canan / Dicle, Murat / Ozagar, Serap Demirelli / Gorpelioglu, Suleyman / Aypak, Cenk

Northern clinics of Istanbul

2024 Volume 11, Issue 2, Page(s) 105–114

Abstract: Objective: Long-term consequences of COVID-19 vary widely, representing a growing global health ... Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2) who admitted to COVID-19 follow-up outpatient clinic between December ... challenge. The aim of this report was to define the presence of symptoms in post-acute-COVID-19 syndrome ...

Abstract	Objective: Long-term consequences of COVID-19 vary widely, representing a growing global health challenge. The aim of this report was to define the presence of symptoms in post-acute-COVID-19 syndrome (PCS) patients and to assess the frequency, associated factors, and the spectrum of persistent symptoms. Methods: In this longitudinal study, 487 adults with a previously diagnosed "Severe Acute Respiratory Syndrome Coronavirus 2" (SARS-CoV-2) who admitted to COVID-19 follow-up outpatient clinic between December 1, 2020 and November 31, 2021 were interviewed face-to-face three times. Data was collected on patient demographics, comorbidities, and symptoms. A questionnaire of 160 questions was asked and organized into the following: identification and consent, socio-demographic/epidemiological characteristics, previous medical history, diagnosis and clinical presentation of acute COVID-19, as well as systematic symptoms. Data were evaluated using univariate comparisons and multiple logistic regression. Results: The most prevalent symptoms among all PCS patients during their initial visit were dyspnea, weakness, forgetfulness, fatigue, and arthralgia respectively. The most common symptoms in patients with 6 months or more time from discharge to follow-up at the first and second visits, appear to be persistent. While incidence rates decreased by the third visit, the five most common symptoms remained the same. The possibility of weakness and arthralgia was found to be higher in non-hospitalized patients. Females were associated with the most common persistent symptoms and the strongest association was with arthralgia. Conclusion: A large number of COVID-19 survivors had continuing symptoms at the first year of post-COVID-19-infection. Neither the presence of comorbidities of the patient nor smoking status were associated with the severity of PCS symptoms. A better understanding of the mechanisms, predisposing factors and evaluation require a multidisciplinary team approach.
Language	English
Publishing date	2024-04-22
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	3031921-3
ISSN	2536-4553 ; 2148-4902
ISSN (online)	2536-4553
ISSN	2148-4902
DOI	10.14744/nci.2023.58908
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito