Article ; Online: Surviving the Rookie Virus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2): The Immunopathology of a SARS-CoV2 Infection.
2021 Volume 30, Page(s) 963689721993769
Abstract: ... 16 million, within which 655 k deaths. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2 ... rate. In this review, we compare the immunopathology among SARS-CoV, Middle East respiratory syndrome ... coronavirus, and SARS-CoV2. SARS-CoV2 is similar to SARS-CoV; it can cause lymphocytopenia and a rising ...
| Abstract | Until July 29th, the number of confirmed coronavirus (COVID-19) cases worldwide has risen to over 16 million, within which 655 k deaths. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) emerges as the 11th global pandemic disease, showing the highest infectivity and lowest infection fatality rate. In this review, we compare the immunopathology among SARS-CoV, Middle East respiratory syndrome coronavirus, and SARS-CoV2. SARS-CoV2 is similar to SARS-CoV; it can cause lymphocytopenia and a rising granulocyte count. Here we point out the human body and concentrated society make for an excellent incubator for virus evolution. Most research energies put into developing the SARS-CoV2 vaccine are trying to block virus infection. Sixty-five percent of severe patients die with multiple organ failure, inflammation, and cytokine storm, which indicates that the patient's immune system maintains functionality. Finding a way to trigger the specific T cell subset and plasmablast in our body is the best shot to get away with SARS-CoV2. |
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| MeSH term(s) | Animals ; COVID-19/immunology ; COVID-19/pathology ; Coronavirus/immunology ; Coronavirus Infections/immunology ; Coronavirus Infections/pathology ; Cytokine Release Syndrome/immunology ; Cytokine Release Syndrome/pathology ; Humans ; Inflammation/immunology ; Inflammation/pathology ; SARS Virus/immunology ; SARS-CoV-2/immunology ; Severe Acute Respiratory Syndrome/immunology ; Severe Acute Respiratory Syndrome/pathology |
| Language | English |
| Publishing date | 2021-04-25 |
| Publishing country | United States |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Review |
| ZDB-ID | 1135816-6 |
| ISSN | 1555-3892 ; 0963-6897 |
| ISSN (online) | 1555-3892 |
| ISSN | 0963-6897 |
| DOI | 10.1177/0963689721993769 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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