Article ; Online: Systemic Coagulopathy in Hospitalized Patients With Coronavirus Disease 2019: A Systematic Review and Meta-Analysis.
2021 Volume 27, Page(s) 1076029620987629
Abstract: Coagulation activation has been reported in several cohorts of patients Coronavirus Disease 2019 ... In this systematic review and meta-analysis, we performed a literature search using PubMed, EMBASE, and Cochrane ... criteria in patients with COVID-19. The primary outcome was the prevalence of systemic coagulopathy ...
| Abstract | Coagulation activation has been reported in several cohorts of patients Coronavirus Disease 2019 (COVID-19). However, the true burden of systemic coagulopathy in COVID-19 remains unknown. In this systematic review and meta-analysis, we performed a literature search using PubMed, EMBASE, and Cochrane Database to identify studies that reported the prevalence of systemic coagulopathy using established criteria in patients with COVID-19. The primary outcome was the prevalence of systemic coagulopathy (disseminated intravascular coagulation [DIC] and/or sepsis-induced coagulopathy [SIC]). Pooled prevalences and 95% confidence intervals [CIs] were calculated using random-effects model. A total of 5 studies including 1210 patients with confirmed COVID-19 were included. The pooled prevalence of systemic coagulopathy was 7.1% (95%CI: 3.2%,15.3%, I |
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| MeSH term(s) | COVID-19/blood ; COVID-19/epidemiology ; Disseminated Intravascular Coagulation/blood ; Disseminated Intravascular Coagulation/epidemiology ; Female ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Male ; Platelet Count ; Prevalence ; SARS-CoV-2/metabolism ; Sepsis/blood ; Sepsis/epidemiology ; Thrombosis/blood ; Thrombosis/epidemiology | |||||
| Chemical Substances | Fibrin Fibrinogen Degradation Products ; fibrin fragment D | |||||
| Language | English | |||||
| Publishing date | 2021-01-14 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Meta-Analysis ; Systematic Review | |||||
| ZDB-ID | 1237357-6 | |||||
| ISSN | 1938-2723 ; 1076-0296 | |||||
| ISSN (online) | 1938-2723 | |||||
| ISSN | 1076-0296 | |||||
| DOI | 10.1177/1076029620987629 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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