Article ; Online: Olfactory and gustatory function impairment in COVID-19 patients: Italian objective multicenter-study.
2020 Volume 42, Issue 7, Page(s) 1560–1569
Abstract: ... and gustatory symptoms and the development of severe COVID-19.: Conclusions: Patients under-report ... in the Literature.: Methods: Multicenter cohort study that involved four Italian hospitals. Three hundred and ... forty-five COVID-19 patients underwent objective chemosensitive evaluation.: Results: Chemosensitive ...
| Abstract | Background: Objective data on chemosensitive disorders during COVID-19 are lacking in the Literature. Methods: Multicenter cohort study that involved four Italian hospitals. Three hundred and forty-five COVID-19 patients underwent objective chemosensitive evaluation. Results: Chemosensitive disorders self-reported by 256 patients (74.2%) but the 30.1% of the 89 patients who did not report dysfunctions proved objectively hyposmic. Twenty-five percentage of patients were seen serious long-lasting complaints. All asymptomatic patients had a slight lowering of the olfactory threshold. No significant correlations were found between the presence and severity of chemosensitive disorders and the severity of the clinical course. On the contrary, there is a significant correlation between the duration of the olfactory and gustatory symptoms and the development of severe COVID-19. Conclusions: Patients under-report the frequency of chemosensitive disorders. Contrary to recent reports, such objective testing refutes the proposal that the presence of olfactory and gustatory dysfunction may predict a milder course, but instead suggests that those with more severe disease neglect such symptoms in the setting of severe respiratory disease. |
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| MeSH term(s) | Adult ; Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Cohort Studies ; Coronavirus Infections/complications ; Female ; Humans ; Italy ; Male ; Middle Aged ; Olfaction Disorders/diagnosis ; Olfaction Disorders/virology ; Pandemics ; Pneumonia, Viral/complications ; SARS-CoV-2 ; Sensory Thresholds ; Severity of Illness Index ; Taste Disorders/diagnosis ; Taste Disorders/virology ; Young Adult |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-05-21 |
| Publishing country | United States |
| Document type | Journal Article ; Multicenter Study |
| ZDB-ID | 645165-2 |
| ISSN | 1097-0347 ; 0148-6403 ; 1043-3074 |
| ISSN (online) | 1097-0347 |
| ISSN | 0148-6403 ; 1043-3074 |
| DOI | 10.1002/hed.26269 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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