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  1. Article ; Online: Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process.

    Vanni, Gianluca / Materazzo, Marco / Pellicciaro, Marco / Ingallinella, Sara / Rho, Maurizio / Santori, Francesca / Cotesta, Maria / Caspi, Jonathan / Makarova, Anna / Pistolese, Chiara Adriana / Buonomo, Oreste Claudio

    In vivo (Athens, Greece)

    2020  Volume 34, Issue 3 Suppl, Page(s) 1651–1659

    Abstract: ... on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19 ... PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC ... could affect patients' decision-making process. ...

    Abstract Background/aim: Coronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19.
    Patients and methods: Between the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason.
    Results: BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients.
    Conclusion: COVID-19-related anxiety could affect patients' decision-making process.
    MeSH term(s) Aged ; Aged, 80 and over ; Anxiety/etiology ; Anxiety/psychology ; Attitude to Health ; Biopsy, Large-Core Needle/methods ; Biopsy, Large-Core Needle/psychology ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/pathology ; Breast Neoplasms/psychology ; Breast Neoplasms/surgery ; COVID-19 ; Coronavirus Infections/psychology ; Decision Making ; Elective Surgical Procedures/psychology ; Fear/psychology ; Female ; Humans ; Italy ; Mammography ; Mastectomy/psychology ; Middle Aged ; Pandemics ; Pneumonia, Viral/psychology ; Retrospective Studies ; Socioeconomic Factors ; Treatment Refusal/psychology ; Ultrasonography, Mammary ; Vacuum
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 807031-3
    ISSN 1791-7549 ; 0258-851X
    ISSN (online) 1791-7549
    ISSN 0258-851X
    DOI 10.21873/invivo.11957
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Breast Cancer and COVID-19: The Effect of Fear on Patients' Decision-making Process

    Vanni, Gianluca / Materazzo, Marco / Pellicciaro, Marco / Ingallinella, Sara / Rho, Maurizio / Santori, Francesca / Cotesta, Maria / Caspi, Jonathan / Makarova, Anna / Pistolese, Chiara Adriana / Buonomo, Oreste Claudio

    In Vivo

    Abstract: ... on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19 ... PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC ... patients' decision-making process. ...

    Abstract BACKGROUND/AIM: Coronavirus-19 (COVID-19) pandemic outbreak is currently having a huge impact on medical resource allocation. Breast Cancer (BC) patients are concerned both with BC treatment and COVID-19. This study aimed to estimate the impact of anxiety among patients, caused by the spreading of COVID-19. PATIENTS AND METHODS: Between the 16th of January and the 20th of March 2020, we retrospectively enrolled 160 patients. Eighty-two patients with a suspected breast lesion (SBL) were divided into two groups: PRE-COVID-19-SBL and POST-COVID-19-SBL. Seventy-eight BC patients were divided into PRE-COVID-19-BC and POST-COVID-19-BC. Patient characteristics including age, marital status, SBL/BC diameter, personal and family history of BC, clinical stage and molecular subtype were recorded. Procedure Refusal (PR) and Surgical Refusal (SR) were also recorded with their reason. RESULTS: BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). Both POST-COVID-19-SBL and POST-COVID-19-BC groups showed higher rates of PR and SR (p=0.0208, p=0.0065 respectively). Infection risk represented primary reason for refusal among POST-COVID-19 patients. CONCLUSION: COVID-19-related anxiety could affect patients' decision-making process.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #543430
    Database COVID19

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  3. Article ; Online: Anxiety and Fear of Breast Cancer Patients During and After the COVID-19 Era.

    Vanni, Gianluca / Materazzo, Marco / Pellicciaro, Marco / Caspi, Jonathan / Portarena, Ilaria / Tacconi, Federico / Noce, Annalisa / Marsella, Valentina Enrica / Granai, Alessandra Vittoria / Pistolese, Chiara Adriana / Buonomo, Oreste Claudio

    Anticancer research

    2023  Volume 43, Issue 7, Page(s) 3255–3263

    Abstract: ... decision-making process.: Patients and methods: Between the 16: Results: BC and SBL analysis showed no difference ... seem to affect the decision-making process of patients with BC. ... resource allocation. While it is clear that the surgery refusal rate of patients with breast cancer (BC) was higher ...

    Abstract Background/aim: Coronavirus-19 (COVID-19) pandemic had a huge impact on medical resource allocation. While it is clear that the surgery refusal rate of patients with breast cancer (BC) was higher during the pandemic, long-term effect of COVID-19 pandemic on hospital admission in the post-pandemic period has not been fully evaluated. This study aimed to estimate how patients' behavior changed following the pandemic and whether the cross-infection risk is still influencing patients' decision-making process.
    Patients and methods: Between the 16
    Results: BC and SBL analysis showed no difference in pre-treatment characteristics (p>0.05). While higher rate of PR and SR rates were reported in COVID-19-SBL and COVID-19-BC groups when compared with PRE-COVID-19 (p=0.003, p=0.013, respectively) and POST-COVID-19 (p=0.005, p=0.004, respectively) groups, no statistical difference was found between PRE-COVID-19 and POST-COVID-19 subanalysis.
    Conclusion: Thanks to preventive measures, COVID-19 does not currently seem to affect the decision-making process of patients with BC.
    MeSH term(s) Humans ; Female ; Breast Neoplasms/surgery ; Breast Neoplasms/pathology ; COVID-19/epidemiology ; Pandemics ; SARS-CoV-2 ; Anxiety ; Fear
    Language English
    Publishing date 2023-06-23
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 604549-2
    ISSN 1791-7530 ; 0250-7005
    ISSN (online) 1791-7530
    ISSN 0250-7005
    DOI 10.21873/anticanres.16500
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Facilitators and barriers to reducing chemotherapy for early-stage breast cancer: a qualitative analysis of interviews with patients and patient advocates.

    Andrews, Courtney / Childers, Timothy C / Wiseman, Kimberly D / Lawhon, Valerie / Ingram, Stacey / Smith, Mary Lou / Wolff, Antonio C / Wagner, Lynne / Rocque, Gabrielle B

    BMC cancer

    2022  Volume 22, Issue 1, Page(s) 141

    Abstract: ... for patients with early-stage breast cancer (EBC). Clinical trials are needed to determine the feasibility ... breast cancer and sixteen patient advocates. Interviews explored potential barriers and facilitators ... lack of information about expected outcomes, (5) fear of regret, and (6) having young children ...

    Abstract Background: As the combination of systemic and targeted chemotherapies is associated with severe adverse side effects and long-term health complications, there is interest in reducing treatment intensity for patients with early-stage breast cancer (EBC). Clinical trials are needed to determine the feasibility of reducing treatment intensity while maintaining 3-year recurrence-free survival of greater than 92%. To recruit participants for these trials, it is important to understand patient perspectives on reducing chemotherapy.
    Methods: We collected qualitative interview data from twenty-four patients with Stage II-III breast cancer and sixteen patient advocates. Interviews explored potential barriers and facilitators to participation in trials testing reduced amounts of chemotherapy. As the COVID-19 pandemic struck during data collection, seventeen participants were asked about the potential impact of COVID-19 on their interest in these trials. Interviews were audio-recorded and transcribed, and researchers used qualitative content analysis to code for dominant themes.
    Results: Seventeen participants (42.5%) expressed interest in participating in a trial of reduced chemotherapy. Barriers to reducing chemotherapy included (1) fear of recurrence and inefficacy, (2) preference for aggressive treatment, (3) disinterest in clinical trials, (4) lack of information about expected outcomes, (5) fear of regret, and (6) having young children. Facilitators included (1) avoiding physical toxicity, (2) understanding the scientific rationale of reducing chemotherapy, (3) confidence in providers, (4) consistent monitoring and the option to increase dosage, (5) fewer financial and logistical challenges, and (6) contributing to scientific knowledge. Of those asked, nearly all participants said they would be more motivated to reduce treatment intensity in the context of COVID-19, primarily to avoid exposure to the virus while receiving treatment.
    Conclusions: Among individuals with EBC, there is significant interest in alleviating treatment-related toxicity by reducing chemotherapeutic intensity. Patients will be more apt to participate in trials testing reduced amounts of chemotherapy if these are framed in terms of customizing treatment to the individual patient and added benefit-reduced toxicities, higher quality of life during treatment and lower risk of long-term complications-rather than in terms of taking treatments away or doing less than the standard of care. Doctor-patient rapport and provider support will be crucial in this process.
    MeSH term(s) Adult ; Aged ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Breast Neoplasms/psychology ; COVID-19/epidemiology ; Decision Making ; Fear/psychology ; Female ; Humans ; Interviews as Topic ; Middle Aged ; Motivation ; Patient Advocacy/psychology ; Qualitative Research ; Quality of Life
    Language English
    Publishing date 2022-02-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041352-X
    ISSN 1471-2407 ; 1471-2407
    ISSN (online) 1471-2407
    ISSN 1471-2407
    DOI 10.1186/s12885-022-09189-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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