Article ; Online: Mimivirus is not a frequent cause of ventilator-associated pneumonia in critically ill patients.
2013 Volume 85, Issue 10, Page(s) 1836–1841
Abstract: ... of ventilator-associated pneumonia, and APMV does not seem to be a frequent cause of ventilator-associated pneumonia. ... of ventilator-associated pneumonia (86 patients). The presence of APMV DNA could not be demonstrated in the bacterial ... samples. Although suspected, APMV appeared not to be present in critically ill patients suspected ...
| Abstract | Acanthamoeba polyphaga mimivirus (APMV) belongs to the amoebae-associated microorganisms. Antibodies to APMV have been found in patients with pneumonia suggesting a potential role as a respiratory pathogen. In addition, positive serology for APMV was associated with an increased duration of mechanical ventilation and intensive care unit stay in patients with ventilator-associated pneumonia. The aim of the present study was to assess the presence of APMV in bronchoalveolar lavage fluid samples of critically ill patients suspected of ventilator-associated pneumonia. The study was conducted in the intensive care unit of the Maastricht University Medical Centre. All consecutive bronchoalveolar lavage fluid samples obtained between January 2005 and October 2009 from patients suspected of ventilator-associated pneumonia were eligible for inclusion. All samples were analyzed by real-time PCR targeting the APMV. A total of 260 bronchoalveolar lavage fluid samples from 214 patients (139 male, 75 female) were included. Bacterial ventilator-associated pneumonia was confirmed microbiologically in 105 out of 260 (40%) suspected episodes of ventilator-associated pneumonia (86 patients). The presence of APMV DNA could not be demonstrated in the bacterial ventilator-associated pneumonia positive or in the bacterial ventilator-associated pneumonia negative bronchoalveolar lavage fluid samples. Although suspected, APMV appeared not to be present in critically ill patients suspected of ventilator-associated pneumonia, and APMV does not seem to be a frequent cause of ventilator-associated pneumonia. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Academic Medical Centers ; Adult ; Aged ; Aged, 80 and over ; Bronchoalveolar Lavage Fluid/virology ; Critical Illness ; DNA Virus Infections/epidemiology ; DNA Virus Infections/virology ; Female ; Humans ; Male ; Middle Aged ; Mimiviridae/isolation & purification ; Netherlands/epidemiology ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/virology ; Retrospective Studies | |||||
| Keywords | covid19 | |||||
| Language | English | |||||
| Publishing date | 2013-07-16 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 752392-0 | |||||
| ISSN | 1096-9071 ; 0146-6615 | |||||
| ISSN (online) | 1096-9071 | |||||
| ISSN | 0146-6615 | |||||
| DOI | 10.1002/jmv.23655 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
Full text online
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 1320: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.