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Article: Changes in Medical Services and Drug Utilization and Associated Costs After Narcolepsy Diagnosis in the United States.

Villa, Kathleen F / Reaven, Nancy L / Funk, Susan E / McGaughey, Karen / Black, Jed

American health & drug benefits

2018  Volume 11, Issue 3, Page(s) 137–145

Abstract: ... Objective: To analyze the changes in medication use, healthcare utilization, and the associated costs after ... diagnosis of narcolepsy. The utilization and cost of medical services and the percentage of patients filling ... associated costs of medical services in the first 3 years after diagnosis. The total costs encompassing ...

Abstract Background: Healthcare utilization and the cost implications associated with undiagnosed and/or misdiagnosed narcolepsy have not been evaluated, and there is scant literature characterizing the newly diagnosed population with narcolepsy with respect to treatment patterns and resource utilization.
Objective: To analyze the changes in medication use, healthcare utilization, and the associated costs after a new diagnosis of narcolepsy.
Methods: In this retrospective cohort study, we used data from the Truven Health Analytics MarketScan Research Databases, between January 2006 and March 2013, to identify patients who had a probable new diagnosis of narcolepsy-defined as a de novo medical claim for a multiple sleep latency test-which was preceded by ≥6 months of continuous insurance and was followed by a de novo diagnosis of narcolepsy. The utilization and cost of medical services and the percentage of patients filling prescriptions for narcolepsy-related medications were evaluated in 3 consecutive 1-year periods from the date of a positive multiple sleep latency test result (ie, index date), and each year's findings were compared with the annualized results from the 6-month preindex period.
Results: A total of 3757 patients who met the definition of a new diagnosis of narcolepsy were identified. The total medical service utilization decreased each year from a preindex average of 28.2 visits per patient per year (PPPY) to 26.9 visits (
Conclusions: In this study, the confirmation of a diagnosis of narcolepsy was associated with decreasing utilization and associated costs of medical services in the first 3 years after diagnosis. The total costs encompassing medical services and pharmacy costs were relatively stable during this period.
Language English
Publishing date 2018-06-01
Publishing country United States
Document type Journal Article
ZDB-ID 2853721-X
ISSN 1942-2970 ; 1942-2962
ISSN (online) 1942-2970
ISSN 1942-2962
Database MEDical Literature Analysis and Retrieval System OnLINE

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