Article ; Online: High-density lipoprotein: does it have a dark side?
2008 Volume 10, Issue 5, Page(s) 121
Abstract: There are proven pleiotropic anti-atherogenic actions of high-density lipoprotein (HDL ... However, in systemic inflammation, HDL can have pro-inflammatory properties that may contribute to accelerated ...
| Abstract | There are proven pleiotropic anti-atherogenic actions of high-density lipoprotein (HDL). However, in systemic inflammation, HDL can have pro-inflammatory properties that may contribute to accelerated atherosclerosis, likely mediated by a change in the structure of HDL to pro-inflammatory HDL (PiHDL). Validation of the technically challenging assay for PiHDL, and confirmation of an association of PiHDL in multiple populations with known risk for atherosclerosis will eventually provide a useful biomarker. Identification of PiHDL in patients with rheumatic disease may help identify patients at risk of accelerated atherosclerosis, and focus our therapeutic interventions. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Animals ; Atherosclerosis/etiology ; Atherosclerosis/metabolism ; Humans ; Inflammation/metabolism ; Lipoproteins, HDL/adverse effects ; Lipoproteins, HDL/chemistry ; Lipoproteins, HDL/metabolism | |||||
| Chemical Substances | Lipoproteins, HDL | |||||
| Language | English | |||||
| Publishing date | 2008-10-31 | |||||
| Publishing country | England | |||||
| Document type | Comment ; Editorial | |||||
| ZDB-ID | 2107602-9 | |||||
| ISSN | 1478-6362 ; 1478-6354 | |||||
| ISSN (online) | 1478-6362 | |||||
| ISSN | 1478-6354 | |||||
| DOI | 10.1186/ar2527 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 5490: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.