LIVIVO - Search results -

Search results

Result 1 - 10 of total 52

Search options

Article: Congenital and acquired long QT syndromes.

Morphet, John

2003 Volume 19, Issue 8, Page(s) 949; author reply 949

MeSH term(s)	Electrocardiography ; Heart Conduction System/abnormalities ; Heart Conduction System/pathology ; Humans ; Long QT Syndrome/congenital ; Long QT Syndrome/etiology ; Long QT Syndrome/pathology ; Torsades de Pointes/congenital ; Torsades de Pointes/etiology ; Torsades de Pointes/pathology
Language	English
Publishing date	2003-07
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	632813-1
ISSN	1916-7075 ; 0828-282X
ISSN (online)	1916-7075
ISSN	0828-282X
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2150: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article: Congenital and acquired long QT syndromes.

Walker, Bruce D / Krahn, Andrew D / Klein, George J / Skanes, Allan C / Wang, Jian / Hegele, Robert A / Yee, Raymond

The Canadian journal of cardiology

2003 Volume 19, Issue 1, Page(s) 76–87

Abstract: Exploration into the underlying genetic causes of congenital long QT syndrome (LQTS) has opened ... of congenital and acquired LQTS. ... from gene and channel studies that have used the congenital syndrome as a springboard for directing research ...

Abstract	Exploration into the underlying genetic causes of congenital long QT syndrome (LQTS) has opened the door to our understanding of repolarization disorders. Expression of LQTS mutations has led to an improved understanding of the mechanisms of arrhythmogenesis, clinical diagnostic tools and channel specific therapy. Further insight into the mechanisms underlying the more common acquired LQTS is emerging from gene and channel studies that have used the congenital syndrome as a springboard for directing research to improve understanding. This review summarizes the clinical, genetic and electrophysiological understanding of congenital and acquired LQTS.
MeSH term(s)	Action Potentials/physiology ; Anti-Arrhythmia Agents/adverse effects ; Anti-Arrhythmia Agents/therapeutic use ; Cardiac Catheterization ; Electrophysiology ; Genetic Linkage ; Heart Conduction System/abnormalities ; Heart Conduction System/drug effects ; Humans ; Long QT Syndrome/congenital ; Long QT Syndrome/genetics ; Long QT Syndrome/therapy ; Sodium Channels/physiology ; Torsades de Pointes/etiology
Chemical Substances	Anti-Arrhythmia Agents ; Sodium Channels
Language	English
Publishing date	2003-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	632813-1
ISSN	1916-7075 ; 0828-282X
ISSN (online)	1916-7075
ISSN	0828-282X
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2150: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Molecular basis of congenital and acquired long QT syndromes.

Ackerman, Michael J

Journal of electrocardiology

2004 Volume 37 Suppl, Page(s) 1–6

MeSH term(s)	Electrocardiography ; Genotype ; Humans ; Ion Channels/genetics ; Long QT Syndrome/congenital ; Long QT Syndrome/genetics ; Long QT Syndrome/physiopathology ; Molecular Biology ; Mutation/genetics ; Phenotype
Chemical Substances	Ion Channels
Language	English
Publishing date	2004-09-03
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	410286-1
ISSN	1532-8430 ; 0022-0736
ISSN (online)	1532-8430
ISSN	0022-0736
DOI	10.1016/j.jelectrocard.2004.08.002
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 701: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: Drug induced QT prolongation: lessons from congenital and acquired long QT syndromes.

Walker, Bruce D / Krahn, Andrew D / Klein, George J / Skanes, Allan C / Yee, Raymond

Current drug targets. Cardiovascular & haematological disorders

2003 Volume 3, Issue 4, Page(s) 327–335

Abstract: ... of congenital long QT syndrome have shed new light in the area of repolarization disorders and their resultant ... long QT syndrome, though the genetic basis of this has not been elucidated in the majority of cases ... cardiac arrhythmias. Drug induced or acquired QT prolongation often represents a latent form of congenital ...

Abstract	Recent developments regarding the underlying genetic and intracardiac ion channel causes of congenital long QT syndrome have shed new light in the area of repolarization disorders and their resultant cardiac arrhythmias. Drug induced or acquired QT prolongation often represents a latent form of congenital long QT syndrome, though the genetic basis of this has not been elucidated in the majority of cases. Understanding this has lead to a new concept of repolarization reserve, a measure of inherent susceptibility to repolarization-mediated arrhythmias. The majority of pharmacologic agents that cause significant QT prolongation have potassium channel blocking characteristics, predominantly affecting the rapidly activating current I(Kr). The list of agents known to affect I(Kr)continues to grow, best monitored through several websites that collate reports of drug-induced QT prolongation and arrhythmias. Discontinuation of the offending agent and supportive care are often all that is necessary when clinical arrhythmias arise.
MeSH term(s)	Anti-Arrhythmia Agents/adverse effects ; Anti-Arrhythmia Agents/therapeutic use ; Female ; Humans ; Long QT Syndrome/chemically induced ; Long QT Syndrome/congenital ; Long QT Syndrome/genetics ; Middle Aged ; Potassium Channels/genetics ; Potassium Channels/physiology ; Torsades de Pointes/chemically induced
Chemical Substances	Anti-Arrhythmia Agents ; Potassium Channels
Language	English
Publishing date	2003-11-11
Publishing country	Netherlands
Document type	Case Reports ; Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	2064870-4
ISSN	1875-5895 ; 1568-0061
ISSN (online)	1875-5895
ISSN	1568-0061
DOI	10.2174/1568006033481393
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 5610: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Mechanisms and management of congenital and acquired long QT syndromes.

Lazzara, R

Archives des maladies du coeur et des vaisseaux

1996 Volume 89 Spec No 1, Page(s) 51–55

Abstract: The long QT syndromes can be divided into congenital and acquired forms. Early afterdepolarizations ... have been identified as triggering mechanisms for both congenital and acquired QT syndromes but reentry ... which enhances K+ current, and Ca2+ blockers or Mg, also a Ca2+ blocker. In the congenital long QT syndromes ...

Abstract	The long QT syndromes can be divided into congenital and acquired forms. Early afterdepolarizations have been identified as triggering mechanisms for both congenital and acquired QT syndromes but reentry may play a role in the perpetuation of the ventricular tachycardia, torsade de pointes. Studies of the ionic mechanisms of early afterdepolarizations have implicated L-type Ca2+ current, persisting Na+ current, and Na+:Ca2+ exchange current related to Ca2+ loading. Different ionic mechanisms may be operative in early afterdepolarizations occuring at different levels of membrane potential in the setting of prolonged repolarization by blocking K+ currents or maintaining non-inactivating Ca2+ or Na+ currents or in early afterdepolarizations due to adrenergic stimulation. In the congenital long QT syndromes, two mutations have recently been discovered in the genes SCN5A and HERG which encode respectively the Na+ channel and a K+ channel conducting the current IKr. It is postulated that the SCN5A mutation leads to a problem with inactivation of Na+ current. In the case of the HERG mutation, the K+ current appears to be diminished. In the case of the acquired long QT syndromes, the therapeutic challenge is to maintain the prolonged repolarization but to interrupt the arrhythmogenic cascade. Current therapies for torsades de pointes include speeding of the heart rate, which enhances K+ current, and Ca2+ blockers or Mg, also a Ca2+ blocker. In the congenital long QT syndromes, therapy in the past has been directed toward reducting adrenergic influence either by betablockade or left cardiac sympathectomy. Recent discoveries open other possibilities such as Na+ channel blockers and methods to increase IKr such as elevation of extracellular K+.
MeSH term(s)	Adrenergic beta-Antagonists/therapeutic use ; Anti-Arrhythmia Agents/pharmacology ; Anti-Arrhythmia Agents/therapeutic use ; Heart Conduction System/physiopathology ; Humans ; Long QT Syndrome/congenital ; Long QT Syndrome/physiopathology ; Long QT Syndrome/therapy ; Mutation ; Pacemaker, Artificial ; Sodium Channels/drug effects ; Sodium Channels/genetics ; Sympathectomy ; Sympathetic Nervous System/physiopathology
Chemical Substances	Adrenergic beta-Antagonists ; Anti-Arrhythmia Agents ; Sodium Channels
Language	English
Publishing date	1996-02
Publishing country	France
Document type	Journal Article ; Review
ZDB-ID	211571-2
ISSN	0003-9683 ; 0301-4525
ISSN	0003-9683 ; 0301-4525
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ui IV Zs.8: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review.

Tardo, Daniel T / Peck, Matthew / Subbiah, Rajesh N / Vandenberg, Jamie I / Hill, Adam P

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc

2022 , Page(s) e13015

Abstract: ... using the terms "LQTS," "long QT syndrome," "QTc prolongation," "prolonged QT," and "T wave," "T wave ... Introduction: QTc prolongation is key in diagnosing long QT syndrome (LQTS), however 25%-50 ... subtypes but its role in acquired LQTS (aLQTS) is unclear.: Methods: Electronic databases were searched ...

Abstract	Introduction: QTc prolongation is key in diagnosing long QT syndrome (LQTS), however 25%-50% with congenital LQTS (cLQTS) demonstrate a normal resting QTc. T wave morphology (TWM) can distinguish cLQTS subtypes but its role in acquired LQTS (aLQTS) is unclear. Methods: Electronic databases were searched using the terms "LQTS," "long QT syndrome," "QTc prolongation," "prolonged QT," and "T wave," "T wave morphology," "T wave pattern," "T wave biomarkers." Whole text articles assessing TWM, independent of QTc, were included. Results: Seventeen studies met criteria. TWM measurements included T-wave amplitude, duration, magnitude, Tpeak-Tend, QTpeak, left and right slope, center of gravity (COG), sigmoidal and polynomial classifiers, repolarizing integral, morphology combination score (MCS) and principal component analysis (PCA); and vectorcardiographic biomarkers. cLQTS were distinguished from controls by sigmoidal and polynomial classifiers, MCS, QTpeak, Tpeak-Tend, left slope; and COG x axis. MCS detected aLQTS more significantly than QTc. Flatness, asymmetry and notching, J-Tpeak; and Tpeak-Tend correlated with QTc in aLQTS. Multichannel block in aLQTS was identified by early repolarization (ERD Conclusion: Numerous TWM biomarkers which supplement QTc assessment were identified. Their diagnostic capabilities include differentiation of genotypes, identification of concealed LQTS, differentiating aLQTS from cLQTS; and determining multichannel versus hERG channel blockade.
Language	English
Publishing date	2022-11-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	1325530-7
ISSN	1542-474X ; 1082-720X
ISSN (online)	1542-474X
ISSN	1082-720X
DOI	10.1111/anec.13015
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4953: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Sex influences on ventricular repolarization duration in normal subjects and in type 1, 2 and 3 long QT syndrome patients: Different effect in acquired and congenital type 2 LQTS.

Extramiana, Fabrice / Badilini, Fabio / Denjoy, Isabelle / Vaglio, Martino / Green, Cynthia L / Kligfield, Paul / Leenhardt, Antoine / Maison-Blanche, Pierre

Journal of electrocardiology

2020 Volume 62, Page(s) 148–154

Abstract: Aim: To evaluate the interaction between sex and rate corrected QT interval (QTc) duration ... in normal subjects after drug-induced QT prolongation and in LQTS patients.: Methods: Semi-automated ... and 33 LQT3 patients (15 females)). A sex specific coefficient was calculated in each group and was ...

Abstract	Aim: To evaluate the interaction between sex and rate corrected QT interval (QTc) duration in normal subjects after drug-induced QT prolongation and in LQTS patients. Methods: Semi-automated measurements were performed on 875 digital ECGs (200 normal subjects off drugs (100 females), 200 normal subjects on Moxifloxacin (100 females), 259 LQT1 patients (161 females), 183 LQT2 patients (100 females) and 33 LQT3 patients (15 females)). A sex specific coefficient was calculated in each group and was used to calculate group specific corrected QT intervals (QTci). Results: The mean sex difference (female minus male) in QTci interval duration was 17 ms 95%CI(12.7; 21.3) in normal subjects, 19 ms (14.5; 23.5) on Moxifloxacin, and 13 ms (4.8; 21.2) in LQT1 patients. The mean difference was 2 ms (-7.9; 11.9) in LQT2 and - 5 ms (-32.2; 22.2) in LQT3 patients (p = 0.0067 for the group and sex interaction). In the subgroup of patients above 15 years and without beta blocker treatment, the sex effect (female minus male) on QTci interval duration was 17 ms (4.1; 29.9) in LQT1 patients. QTc duration was not different between sex in LQT2 and in LQT3 patients (mean difference - 3 ms (-21.6; 15.6) and 12 ms (-28.4; 52.4), respectively) (p = 0.0191 for group and sex interaction). Conclusions: The interaction between sex and QTc interval is preserved in type 1 LQTS and drug-induced QTc prolongation but blurred in type 2 LQTS. Further experimental studies are warranted to better understand the interaction of sexual hormones with malfunctioning KCNH2 encoded repolarizing potassium channel.
MeSH term(s)	Adrenergic beta-Antagonists ; Electrocardiography ; Female ; Humans ; Long QT Syndrome/diagnosis ; Male
Chemical Substances	Adrenergic beta-Antagonists
Language	English
Publishing date	2020-08-26
Publishing country	United States
Document type	Journal Article
ZDB-ID	410286-1
ISSN	1532-8430 ; 0022-0736
ISSN (online)	1532-8430
ISSN	0022-0736
DOI	10.1016/j.jelectrocard.2020.08.016
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 701: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: The application of root mean square electrocardiography (RMS ECG) for the detection of acquired and congenital long QT syndrome.

Lux, Robert L / Sower, Christopher Todd / Allen, Nancy / Etheridge, Susan P / Tristani-Firouzi, Martin / Saarel, Elizabeth V

PloS one

2014 Volume 9, Issue 1, Page(s) e85689

Abstract: ... Long QT Syndrome (LQTS).: Methods: RMS ECG signals were derived from high-resolution 24 hour Holter monitor ... automatically measured using custom software and compared to traditional QT measures using lead II.: Results ... of RMS ECG to assess ventricular repolarization in humans in the setting of drug-induced and congenital ...

Abstract	Background: Precise measurement of the QT interval is often hampered by difficulty determining the end of the low amplitude T wave. Root mean square electrocardiography (RMS ECG) provides a novel alternative measure of ventricular repolarization. Experimental data have shown that the interval between the RMS ECG QRS and T wave peaks (RTPK) closely reflects the mean ventricular action potential duration while the RMS T wave width (TW) tracks the dispersion of repolarization timing. Here, we tested the precision of RMS ECG to assess ventricular repolarization in humans in the setting of drug-induced and congenital Long QT Syndrome (LQTS). Methods: RMS ECG signals were derived from high-resolution 24 hour Holter monitor recordings from 68 subjects after receiving placebo and moxifloxacin and from standard 12 lead ECGs obtained in 97 subjects with LQTS and 97 age- and sex-matched controls. RTPK, QTRMS and RMS TW intervals were automatically measured using custom software and compared to traditional QT measures using lead II. Results: All measures of repolarization were prolonged during moxifloxacin administration and in LQTS subjects, but the variance of RMS intervals was significantly smaller than traditional lead II measurements. TW was prolonged during moxifloxacin and in subjects with LQT-2, but not LQT-1 or LQT-3. Conclusion: These data validate the application of RMS ECG for the detection of drug-induced and congenital LQTS. RMS ECG measurements are more precise than the current standard of care lead II measurements.
MeSH term(s)	Adolescent ; Adult ; Cardiotonic Agents/therapeutic use ; Case-Control Studies ; Child ; Child, Preschool ; Data Interpretation, Statistical ; Electrocardiography, Ambulatory/methods ; Female ; Fluoroquinolones/therapeutic use ; Heart Rate ; Humans ; Long QT Syndrome/diagnosis ; Long QT Syndrome/drug therapy ; Long QT Syndrome/physiopathology ; Male ; Middle Aged ; Moxifloxacin ; Randomized Controlled Trials as Topic ; Young Adult
Chemical Substances	Cardiotonic Agents ; Fluoroquinolones ; Moxifloxacin (U188XYD42P)
Language	English
Publishing date	2014-01-15
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1932-6203
ISSN (online)	1932-6203
DOI	10.1371/journal.pone.0085689
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Molecular aspects of the congenital and acquired Long QT Syndrome: clinical implications.

Saenen, J B / Vrints, C J

Journal of molecular and cellular cardiology

2008 Volume 44, Issue 4, Page(s) 633–646

Abstract: The Long QT Syndrome (LQTS) is a complex and multi-factorial disorder that predisposes to life ... threatening ventricular arrhythmias. Both hereditary and acquired subforms have been identified over the years ... Recently, it has become clear that the interaction of multiple acquired and genetic aetiologic factors (e.g ...

Abstract	The Long QT Syndrome (LQTS) is a complex and multi-factorial disorder that predisposes to life-threatening ventricular arrhythmias. Both hereditary and acquired subforms have been identified over the years. Recently, it has become clear that the interaction of multiple acquired and genetic aetiologic factors (e.g. disease modifiers) play an important role in differentiating genotype into a continuous spectrum of clinical or subclinical phenotypes. The genotype-phenotype correlation thereby remains very unpredictable in asymptomatic patients, raising important concerns for clinical practice and also for drug development. Therefore, this review aims at providing a comprehensive overview on LQTS highlighting the molecular mechanisms of arrhythmogenesis involved in both the hereditary and the acquired subtypes of the disorder. From this perspective this manuscript then focuses on how the genotype translates into phenotype. A logical overview is provided with the multitude of hereditary and acquired factors that are involved and of the complexity of the interactions that ultimately result in the heterogeneous expressivity and the unpredictability of the phenotype. Based on recent basic and clinical data this review further aims at providing an update on the clinical properties and management of LQT patients including diagnostic work-up and therapy.
MeSH term(s)	Genotype ; Humans ; Long QT Syndrome/congenital ; Long QT Syndrome/diagnosis ; Long QT Syndrome/pathology ; Long QT Syndrome/therapy ; Phenotype
Language	English
Publishing date	2008-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	80157-4
ISSN	1095-8584 ; 0022-2828
ISSN (online)	1095-8584
ISSN	0022-2828
DOI	10.1016/j.yjmcc.2008.01.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 426: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: The application of root mean square electrocardiography (RMS ECG) for the detection of acquired and congenital long QT syndrome.

Robert L Lux / Christopher Todd Sower / Nancy Allen / Susan P Etheridge / Martin Tristani-Firouzi / Elizabeth V Saarel

PLoS ONE, Vol 9, Iss 1, p e

2014 Volume 85689

Abstract: ... Long QT Syndrome (LQTS). METHODS: RMS ECG signals were derived from high-resolution 24 hour Holter monitor ... automatically measured using custom software and compared to traditional QT measures using lead II. RESULTS ... of RMS ECG to assess ventricular repolarization in humans in the setting of drug-induced and congenital ...

Abstract	BACKGROUND: Precise measurement of the QT interval is often hampered by difficulty determining the end of the low amplitude T wave. Root mean square electrocardiography (RMS ECG) provides a novel alternative measure of ventricular repolarization. Experimental data have shown that the interval between the RMS ECG QRS and T wave peaks (RTPK) closely reflects the mean ventricular action potential duration while the RMS T wave width (TW) tracks the dispersion of repolarization timing. Here, we tested the precision of RMS ECG to assess ventricular repolarization in humans in the setting of drug-induced and congenital Long QT Syndrome (LQTS). METHODS: RMS ECG signals were derived from high-resolution 24 hour Holter monitor recordings from 68 subjects after receiving placebo and moxifloxacin and from standard 12 lead ECGs obtained in 97 subjects with LQTS and 97 age- and sex-matched controls. RTPK, QTRMS and RMS TW intervals were automatically measured using custom software and compared to traditional QT measures using lead II. RESULTS: All measures of repolarization were prolonged during moxifloxacin administration and in LQTS subjects, but the variance of RMS intervals was significantly smaller than traditional lead II measurements. TW was prolonged during moxifloxacin and in subjects with LQT-2, but not LQT-1 or LQT-3. CONCLUSION: These data validate the application of RMS ECG for the detection of drug-induced and congenital LQTS. RMS ECG measurements are more precise than the current standard of care lead II measurements.
Keywords	Medicine ; R ; Science ; Q
Subject code	551
Language	English
Publishing date	2014-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED