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  1. Article ; Online: Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis.

    Wang, Bolin / Li, Ruobao / Lu, Zhong / Huang, Yan

    Aging

    2020  Volume 12, Issue 7, Page(s) 6049–6057

    Abstract: ... factors associated with COVID-19 patients. The meta-analysis revealed no correlation between increased risk of COVID ... whether the presence of common comorbidities increases COVID-19 patients' risk. A literature search was performed using ... but relationship between comorbidity and patients with COVID-19 still not clear. The aim was to explore ...

    Abstract Currently, the number of patients with coronavirus disease 2019 (COVID-19) has increased rapidly, but relationship between comorbidity and patients with COVID-19 still not clear. The aim was to explore whether the presence of common comorbidities increases COVID-19 patients' risk. A literature search was performed using the electronic platforms (PubMed, Cochrane Library, Embase, and other databases) to obtain relevant research studies published up to March 1, 2020. Relevant data of research endpoints in each study were extracted and merged. All data analysis was performed using Stata12.0 software. A total of 1558 patients with COVID-19 in 6 studies were enrolled in our meta-analysis eventually. Hypertension (OR: 2.29, P<0.001), diabetes (OR: 2.47, P<0.001), chronic obstructive pulmonary disease (COPD) (OR: 5.97, P<0.001), cardiovascular disease (OR: 2.93, P<0.001), and cerebrovascular disease (OR:3.89, P=0.002)were independent risk factors associated with COVID-19 patients. The meta-analysis revealed no correlation between increased risk of COVID-19 and liver disease, malignancy, or renal disease. Hypertension, diabetes, COPD, cardiovascular disease, and cerebrovascular disease are major risk factors for patients with COVID-19. Knowledge of these risk factors can be a resource for clinicians in the early appropriate medical management of patients with COVID-19.
    MeSH term(s) COVID-19 ; Comorbidity ; Coronavirus Infections/epidemiology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; Risk Assessment
    Keywords covid19
    Language English
    Publishing date 2020-04-08
    Publishing country United States
    Document type Journal Article ; Meta-Analysis
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.103000
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Does comorbidity increase the risk of patients with COVID-19: evidence from meta-analysis

    Wang, Bolin / Li, Ruobao / Lu, Zhong / Huang, Yan

    Aging (Albany NY)

    Abstract: ... factors associated with COVID-19 patients. The meta-analysis revealed no correlation between increased risk of COVID ... whether the presence of common comorbidities increases COVID-19 patients' risk. A literature search was performed using ... but relationship between comorbidity and patients with COVID-19 still not clear. The aim was to explore ...

    Abstract Currently, the number of patients with coronavirus disease 2019 (COVID-19) has increased rapidly, but relationship between comorbidity and patients with COVID-19 still not clear. The aim was to explore whether the presence of common comorbidities increases COVID-19 patients' risk. A literature search was performed using the electronic platforms (PubMed, Cochrane Library, Embase, and other databases) to obtain relevant research studies published up to March 1, 2020. Relevant data of research endpoints in each study were extracted and merged. All data analysis was performed using Stata12.0 software. A total of 1558 patients with COVID-19 in 6 studies were enrolled in our meta-analysis eventually. Hypertension (OR: 2.29, P<0.001), diabetes (OR: 2.47, P<0.001), chronic obstructive pulmonary disease (COPD) (OR: 5.97, P<0.001), cardiovascular disease (OR: 2.93, P<0.001), and cerebrovascular disease (OR:3.89, P=0.002)were independent risk factors associated with COVID-19 patients. The meta-analysis revealed no correlation between increased risk of COVID-19 and liver disease, malignancy, or renal disease. Hypertension, diabetes, COPD, cardiovascular disease, and cerebrovascular disease are major risk factors for patients with COVID-19. Knowledge of these risk factors can be a resource for clinicians in the early appropriate medical management of patients with COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #46003
    Database COVID19

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  3. Article ; Online: Does Asthma Increase the Mortality of Patients with COVID-19?: A Systematic Review and Meta-Analysis.

    Wang, Yuanyuan / Chen, Jingjing / Chen, Wei / Liu, Ling / Dong, Mei / Ji, Juan / Hu, Die / Zhang, Nianzhi

    International archives of allergy and immunology

    2020  Volume 182, Issue 1, Page(s) 76–82

    Abstract: ... indicates that asthma as a comorbidity may not increase the mortality of COVID-19. Data on the influence ... retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 ... data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma ...

    Abstract The purpose of this systematic review and meta-analysis was to explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma. The databases PubMed, Scopus, Embase, Google Scholar, and medRxiv.org were searched for studies comparing the clinical outcomes of asthmatic patients with those of nonasthmatic patients diagnosed with COVID-19. Mortality data were summarized using the Mantel-Haenszel OR with 95% CI in a random-effects model. Five retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 nonasthmatic patients indicated that the presence of asthma had no significant effect on mortality (OR = 0.96; 95% CI 0.70-1.30; I2 = 0%; p = 0.79). Results were stable in a sensitivity analysis. A descriptive analysis of other clinical outcomes indicated no difference in the duration of hospitalization and the risk of intensive care unit (ICU) transfer between asthmatic and nonasthmatic patients. To conclude, preliminary data indicates that asthma as a comorbidity may not increase the mortality of COVID-19. Data on the influence of asthma on the risk of hospitalization, the duration of hospitalization, the requirement of ICU admission, and disease severity is still too limited to draw any strong conclusions. Further studies with a larger sample size are required to establish strong evidence.
    MeSH term(s) Asthma/mortality ; COVID-19/mortality ; Comorbidity ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-09-22
    Publishing country Switzerland
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 1108932-5
    ISSN 1423-0097 ; 1018-2438
    ISSN (online) 1423-0097
    ISSN 1018-2438
    DOI 10.1159/000510953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Does Asthma Increase the Mortality of Patients with COVID-19?: A Systematic Review and Meta-Analysis

    Wang, Yuanyuan / Chen, Jingjing / Chen, Wei / Liu, Ling / Dong, Mei / Ji, Juan / Hu, Die / Zhang, Nianzhi

    Int Arch Allergy Immunol

    Abstract: ... indicates that asthma as a comorbidity may not increase the mortality of COVID-19. Data on the influence ... retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 ... data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma ...

    Abstract The purpose of this systematic review and meta-analysis was to explore the literature and collate data comparing the mortality of coronavirus disease 2019 (COVID-19) patients with and without asthma. The databases PubMed, Scopus, Embase, Google Scholar, and medRxiv.org were searched for studies comparing the clinical outcomes of asthmatic patients with those of nonasthmatic patients diagnosed with COVID-19. Mortality data were summarized using the Mantel-Haenszel OR with 95% CI in a random-effects model. Five retrospective studies met the inclusion criteria. A meta-analysis of data from 744 asthmatic patients and 8,151 nonasthmatic patients indicated that the presence of asthma had no significant effect on mortality (OR = 0.96; 95% CI 0.70-1.30; I2 = 0%; p = 0.79). Results were stable in a sensitivity analysis. A descriptive analysis of other clinical outcomes indicated no difference in the duration of hospitalization and the risk of intensive care unit (ICU) transfer between asthmatic and nonasthmatic patients. To conclude, preliminary data indicates that asthma as a comorbidity may not increase the mortality of COVID-19. Data on the influence of asthma on the risk of hospitalization, the duration of hospitalization, the requirement of ICU admission, and disease severity is still too limited to draw any strong conclusions. Further studies with a larger sample size are required to establish strong evidence.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #788276
    Database COVID19

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

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