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  1. Article ; Online: Changes in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak.

    Wang, Yuanyuan / Hu, Zhishan / Feng, Yi / Wilson, Amanda / Chen, Runsen

    Molecular psychiatry

    2020  Volume 25, Issue 12, Page(s) 3140–3149

    Abstract: ... properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms ... throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and ... The current study investigated the mechanism and changes in psychopathology symptoms ...

    Abstract The current study investigated the mechanism and changes in psychopathology symptoms throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and the after peak stages, with 2540 participants were recruited from February 6 to 16, 2020, and 2543 participants were recruited from April 25 to May 5, 2020. The network models were created to explore the relationship between psychopathology symptoms both within and across anxiety and depression, with anxiety measured by the Generalized Anxiety Disorder-7 and depression measured by the Patient Health Questionnaire-9. Symptom network analysis was conducted to evaluate network and bridge centrality, and the network properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms such as impaired motor skills, restlessness, and inability to relax exhibited high centrality during the outbreak, which still relatively high but showed substantial remission during after peak stage (in terms of strength, betweenness, or bridge centrality). Meanwhile, symptoms of irritability (strength, betweenness, or bridge centrality) and loss of energy (bridge centrality) played an important role in the network after the peak of the pandemic. This study provides novel insights into the changes in central features during the different COVID-19 stages and highlights motor-related symptoms as bridge symptoms, which could activate the connection between anxiety and depression. The results revealed that restrictions on movement were associated with worsen in psychomotor symptoms, indicating that future psychological interventions should target motor-related symptoms as priority.
    MeSH term(s) Anxiety/diagnosis ; Anxiety/epidemiology ; COVID-19/epidemiology ; Depression/diagnosis ; Depression/epidemiology ; Humans ; Models, Psychological ; Pandemics ; Psychiatric Status Rating Scales ; SARS-CoV-2 ; Time Factors
    Keywords covid19
    Language English
    Publishing date 2020-09-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 1330655-8
    ISSN 1476-5578 ; 1359-4184
    ISSN (online) 1476-5578
    ISSN 1359-4184
    DOI 10.1038/s41380-020-00881-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Changes in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak

    Wang, Yuanyuan / Hu, Zhishan / Feng, Yi / Wilson, Amanda / Chen, Runsen

    Molecular Psychiatry ; ISSN 1359-4184 1476-5578

    2020  

    Abstract: ... properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms ... throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and ... Abstract The current study investigated the mechanism and changes in psychopathology symptoms ...

    Abstract Abstract The current study investigated the mechanism and changes in psychopathology symptoms throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and the after peak stages, with 2540 participants were recruited from February 6 to 16, 2020, and 2543 participants were recruited from April 25 to May 5, 2020. The network models were created to explore the relationship between psychopathology symptoms both within and across anxiety and depression, with anxiety measured by the Generalized Anxiety Disorder-7 and depression measured by the Patient Health Questionnaire-9. Symptom network analysis was conducted to evaluate network and bridge centrality, and the network properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms such as impaired motor skills, restlessness, and inability to relax exhibited high centrality during the outbreak, which still relatively high but showed substantial remission during after peak stage (in terms of strength, betweenness, or bridge centrality). Meanwhile, symptoms of irritability (strength, betweenness, or bridge centrality) and loss of energy (bridge centrality) played an important role in the network after the peak of the pandemic. This study provides novel insights into the changes in central features during the different COVID-19 stages and highlights motor-related symptoms as bridge symptoms, which could activate the connection between anxiety and depression. The results revealed that restrictions on movement were associated with worsen in psychomotor symptoms, indicating that future psychological interventions should target motor-related symptoms as priority.
    Keywords Molecular Biology ; Cellular and Molecular Neuroscience ; Psychiatry and Mental health ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1038/s41380-020-00881-6
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Changes in network centrality of psychopathology symptoms between the COVID-19 outbreak and after peak

    Wang, Yuanyuan / Hu, Zhishan / Feng, Yi / Wilson, Amanda / Chen, Runsen

    Mol. psychiatry

    Abstract: ... properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms ... throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and ... The current study investigated the mechanism and changes in psychopathology symptoms ...

    Abstract The current study investigated the mechanism and changes in psychopathology symptoms throughout the COVID-19 outbreak and after peak. Two studies were conducted separately in China during outbreak and the after peak stages, with 2540 participants were recruited from February 6 to 16, 2020, and 2543 participants were recruited from April 25 to May 5, 2020. The network models were created to explore the relationship between psychopathology symptoms both within and across anxiety and depression, with anxiety measured by the Generalized Anxiety Disorder-7 and depression measured by the Patient Health Questionnaire-9. Symptom network analysis was conducted to evaluate network and bridge centrality, and the network properties were compared between the outbreak and after peak. Noticeably, psychomotor symptoms such as impaired motor skills, restlessness, and inability to relax exhibited high centrality during the outbreak, which still relatively high but showed substantial remission during after peak stage (in terms of strength, betweenness, or bridge centrality). Meanwhile, symptoms of irritability (strength, betweenness, or bridge centrality) and loss of energy (bridge centrality) played an important role in the network after the peak of the pandemic. This study provides novel insights into the changes in central features during the different COVID-19 stages and highlights motor-related symptoms as bridge symptoms, which could activate the connection between anxiety and depression. The results revealed that restrictions on movement were associated with worsen in psychomotor symptoms, indicating that future psychological interventions should target motor-related symptoms as priority.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #766056
    Database COVID19

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