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  1. Article ; Online: Yeast as a promising heterologous host for steroid bioproduction.

    Xu, Shanhui / Li, Yanran

    Journal of industrial microbiology & biotechnology

    2020  Volume 47, Issue 9-10, Page(s) 829–843

    Abstract: ... steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction ... been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols ... of using yeast to synthesize various steroids, and discuss the structural diversity that the current ...

    Abstract With the rapid development of synthetic biology and metabolic engineering technologies, yeast has been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols are essential components of cell membrane, and are the precursors for the biosynthesis of steroid hormones, signaling molecules, and defense molecules in the higher eukaryotes, which are of pharmaceutical and agricultural significance. In this mini-review, we summarize the recent engineering efforts of using yeast to synthesize various steroids, and discuss the structural diversity that the current steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction platform of various steroids from higher eukaryotes.
    MeSH term(s) Metabolic Engineering ; Saccharomyces cerevisiae/metabolism ; Sterols/chemistry ; Synthetic Biology
    Chemical Substances Sterols
    Keywords covid19
    Language English
    Publishing date 2020-07-13
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1482484-X
    ISSN 1476-5535 ; 1367-5435
    ISSN (online) 1476-5535
    ISSN 1367-5435
    DOI 10.1007/s10295-020-02291-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Yeast as a promising heterologous host for steroid bioproduction

    Xu, Shanhui / Li, Yanran

    J. ind. microbiol. biotech

    Abstract: ... steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction ... been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols ... of using yeast to synthesize various steroids, and discuss the structural diversity that the current ...

    Abstract With the rapid development of synthetic biology and metabolic engineering technologies, yeast has been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols are essential components of cell membrane, and are the precursors for the biosynthesis of steroid hormones, signaling molecules, and defense molecules in the higher eukaryotes, which are of pharmaceutical and agricultural significance. In this mini-review, we summarize the recent engineering efforts of using yeast to synthesize various steroids, and discuss the structural diversity that the current steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction platform of various steroids from higher eukaryotes.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #641325
    Database COVID19

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  3. Article: Yeast as a promising heterologous host for steroid bioproduction

    Xu, Shanhui / Li, Yanran

    Journal of industrial microbiology & biotechnology. 2020 Oct., v. 47, no. 9-10

    2020  

    Abstract: ... steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction ... been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols ... of using yeast to synthesize various steroids, and discuss the structural diversity that the current ...

    Abstract With the rapid development of synthetic biology and metabolic engineering technologies, yeast has been generally considered as promising hosts for the bioproduction of secondary metabolites. Sterols are essential components of cell membrane, and are the precursors for the biosynthesis of steroid hormones, signaling molecules, and defense molecules in the higher eukaryotes, which are of pharmaceutical and agricultural significance. In this mini-review, we summarize the recent engineering efforts of using yeast to synthesize various steroids, and discuss the structural diversity that the current steroid-producing yeast can achieve, the challenge and the potential of using yeast as the bioproduction platform of various steroids from higher eukaryotes.
    Keywords biosynthesis ; biotechnology ; cell membranes ; eukaryotic cells ; genetically modified organisms ; industrial microbiology ; secondary metabolites ; sterols ; synthetic biology ; yeasts
    Language English
    Dates of publication 2020-10
    Size p. 829-843.
    Publishing place Springer International Publishing
    Document type Article
    Note NAL-AP-2-clean ; Review
    ZDB-ID 1482484-X
    ISSN 1476-5535 ; 1367-5435
    ISSN (online) 1476-5535
    ISSN 1367-5435
    DOI 10.1007/s10295-020-02291-7
    Database NAL-Catalogue (AGRICOLA)

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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