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  1. Article ; Online: COVID-19 infection in patients with connective tissue disease: A multicity study in Hubei province, China.

    Ye, Cong / Zhong, Jixin / Cai, Shaozhe / Dong, Li / Li, Chuanjing / Hou, Xiaoqiang / Chen, Xiaoqi / Zhang, Anbing / Chen, Wenli / He, Dongchu / Zhou, Tao / Shang, Guilian / Chu, Aichun / Li, Huiling / Liu, Qihuan / Wu, Bin / Yu, Xiangdong / Peng, Tao / Wen, Cheng /
    Huang, Gang Hong / Huang, Hao / Huang, Qin / Su, Linchong / Chen, Wenping / Yang, Huiqin / Dong, Lingli

    MedComm

    2021  Volume 2, Issue 1, Page(s) 82–90

    Abstract: ... with connective tissue disease (CTD) tend to be more severe after COVID-19 infection ( ... have not been reported. Here, we identified 100 rheumatic patients from 18,786 COVID-19 patients ... hospitalized in 23 centers affiliated to Hubei COVID-19 Rheumatology Alliance between January 1 and April 1 ...

    Abstract Novel Coronavirus disease 2019 (COVID-19) has spread rapidly around the world. Individuals with immune dysregulation and/or on immunosuppressive therapy, such as rheumatic patients, are considered at greater risk for infections. However, the risks of patients with each subcategory of rheumatic diseases have not been reported. Here, we identified 100 rheumatic patients from 18,786 COVID-19 patients hospitalized in 23 centers affiliated to Hubei COVID-19 Rheumatology Alliance between January 1 and April 1, 2020. Demographic information, medical history, length of hospital stay, classification of disease severity, symptoms and signs, laboratory tests, disease outcome, computed tomography, and treatments information were collected. Compared to gout and ankylosing spondylitis (AS) patients, patients with connective tissue disease (CTD) tend to be more severe after COVID-19 infection (
    Language English
    Publishing date 2021-02-04
    Publishing country China
    Document type Journal Article
    ISSN 2688-2663
    ISSN (online) 2688-2663
    DOI 10.1002/mco2.56
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID19 infection in patients with connective tissue disease

    Cong Ye / Jixin Zhong / Shaozhe Cai / Li Dong / Chuanjing Li / Xiaoqiang Hou / Xiaoqi Chen / Anbing Zhang / Wenli Chen / Dongchu He / Tao Zhou / Guilian Shang / Aichun Chu / Huiling Li / Qihuan Liu / Bin Wu / Xiangdong Yu / Tao Peng / Cheng Wen /
    Gang Hong Huang / Hao Huang / Qin Huang / Linchong Su / Wenping Chen / Huiqin Yang / Lingli Dong

    MedComm, Vol 2, Iss 1, Pp 82-

    A multicity study in Hubei province, China

    2021  Volume 90

    Abstract: ... with connective tissue disease (CTD) tend to be more severe after COVID19 infection (p = 0.081). CTD patients also had lower ... have not been reported. Here, we identified 100 rheumatic patients from 18,786 COVID19 patients ... hospitalized in 23 centers affiliated to Hubei COVID19 Rheumatology Alliance between January 1 and April 1 ...

    Abstract Abstract Novel Coronavirus disease 2019 (COVID19) has spread rapidly around the world. Individuals with immune dysregulation and/or on immunosuppressive therapy, such as rheumatic patients, are considered at greater risk for infections. However, the risks of patients with each subcategory of rheumatic diseases have not been reported. Here, we identified 100 rheumatic patients from 18,786 COVID19 patients hospitalized in 23 centers affiliated to Hubei COVID19 Rheumatology Alliance between January 1 and April 1, 2020. Demographic information, medical history, length of hospital stay, classification of disease severity, symptoms and signs, laboratory tests, disease outcome, computed tomography, and treatments information were collected. Compared to gout and ankylosing spondylitis (AS) patients, patients with connective tissue disease (CTD) tend to be more severe after COVID19 infection (p = 0.081). CTD patients also had lower lymphocyte counts, hemoglobin, and platelet counts (p values were 0.033, < 0.001, and 0.071, respectively). Hydroxychloroquine therapy and low‐ to medium‐dose glucocorticoids before COVID19 diagnosis reduced the progression of COVID19 to severe/critical conditions (p = 0.001 for hydroxychloroquine; p = 0.006 for glucocorticoids). Our data suggests that COVID19 in CTD patients may be more severe compared to patients with AS or gout.
    Keywords connective tissue disease ; COVID‐19 ; hydroxychloroquine ; rheumatic disease ; SARS‐CoV‐2 ; Medicine ; R
    Subject code 610 ; 616
    Language English
    Publishing date 2021-03-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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