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Article ; Online: Transient monocular visual impairment as an initial symptom of COVID-19 infection in an individual with multiple sclerosis receiving teriflunomide.

Yetkin, Mehmet Fatih / Yetkin, Nur Aleyna / Akcakoyunlu, Merve / Mirza, Meral

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

2021  Volume 42, Issue 5, Page(s) 1661–1664

Abstract: ... of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not ... in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people ... throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various ...

Abstract In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Since the outbreak of the pandemic, in addition to the well-known COVID-19 symptoms, various neurological symptoms have been also described in patients with COVID-19. Here, we report an unusual presentation of COVID-19 infection in a teriflunomide-treated individual with multiple sclerosis (MS) who did not interrupt teriflunomide treatment during the infection. The course of the infection was mild in this case as in other reported teriflunomide-treated individuals with COVID-19. COVID-19's presentation may be unusual in people with MS (pwMS). It can also be concluded that teriflunomide may be considered a safe disease-modifying treatment option during the pandemic.
MeSH term(s) COVID-19 ; China ; Crotonates ; Humans ; Hydroxybutyrates ; Immunologic Factors ; Multiple Sclerosis/complications ; Multiple Sclerosis/drug therapy ; Nitriles ; SARS-CoV-2 ; Toluidines ; Vision Disorders
Chemical Substances Crotonates ; Hydroxybutyrates ; Immunologic Factors ; Nitriles ; Toluidines ; teriflunomide (1C058IKG3B)
Language English
Publishing date 2021-02-03
Publishing country Italy
Document type Case Reports ; Journal Article
ZDB-ID 2016546-8
ISSN 1590-3478 ; 1590-1874
ISSN (online) 1590-3478
ISSN 1590-1874
DOI 10.1007/s10072-021-05097-2
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