Article ; Online: Pouchitis
International Journal of General Medicine, Vol Volume 14, Pp 3871-
Clinical Features, Diagnosis, and Treatment
2021 Volume 3879
Abstract: ... for ulcerative colitis patients that require colectomy. Pouchitis is a non-specific inflammation of the ileal reservoir ... for ulcerative colitis. The aetiology is still unknown, but many risk factors have been individuated. Pouchitis can be ... of pouchitis is pivotal. Most of the patients consistently respond to antibiotic therapy, but management ...
Abstract | Paolo Gionchetti, Carlo Calabrese, Silvio Laureti, Gilberto Poggioli, Fernando Rizzello IRCCS Azienda Ospedaliero-Universitaria di Bologna, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Bologna, ItaliaCorrespondence: Paolo GionchettiDIMEC, Via Massarenti 9, Bologna, 40138, ItaliaEmail paolo.gionchetti@unibo.itAbstract: Procto-colectomy with an ileal pouch anal anastomosis is the procedure of choice for ulcerative colitis patients that require colectomy. Pouchitis is a non-specific inflammation of the ileal reservoir, and the most common, inflammatory and long-term, complication after pouch surgery for ulcerative colitis. The aetiology is still unknown, but many risk factors have been individuated. Pouchitis can be classified based on aetiology, duration, clinical course, and response to antibiotic therapy. Accurate diagnosis and classification is the key factor for an adequate management, and exclusion of secondary causes of pouchitis is pivotal. Most of the patients consistently respond to antibiotic therapy, but management of the subgroup of patients with chronic-antibiotic-resistant-pouchitis is still challenging, being this entity one of the major causes of pouch failure.Keywords: pouchitis, chronic antibiotic refractory pouchitis, classification, diagnosis, management |
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Keywords | pouchitis ; chronic antibiotic refractory pouchitis ; classification ; diagnosis ; management ; Medicine (General) ; R5-920 |
Subject code | 610 |
Language | English |
Publishing date | 2021-07-01T00:00:00Z |
Publisher | Dove Medical Press |
Document type | Article ; Online |
Database | BASE - Bielefeld Academic Search Engine (life sciences selection) |
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