Article ; Online: Viral loads in throat and anal swabs in children infected with SARS-CoV-2.
Emerging microbes & infections
2020 Volume 9, Issue 1, Page(s) 1233–1237
Abstract: ... assay on throat and anal swabs remain limited in paediatric patients. Here, we retrospectively reviewed ... positive rate: 78.2% on throat swabs vs. 52.6% on anal swabs, McNemar Test ... severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, data about the consistent performance of RT-PCR ...
| Abstract | Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay on anal swabs was recently reported to be persistently positive even after throat testing was negative during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, data about the consistent performance of RT-PCR assay on throat and anal swabs remain limited in paediatric patients. Here, we retrospectively reviewed RT-PCR-testing results of 212 paediatric patients with suspected SARS-CoV-2 infection at Wuhan Children's Hospital. The diagnostic potential of these two types of specimens showed significant difference (positive rate: 78.2% on throat swabs vs. 52.6% on anal swabs, McNemar Test |
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| MeSH term(s) | Anal Canal/virology ; Betacoronavirus/genetics ; Betacoronavirus/isolation & purification ; COVID-19 ; Child ; China/epidemiology ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/virology ; Female ; Humans ; Male ; Pandemics ; Pharynx/virology ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/virology ; Real-Time Polymerase Chain Reaction/standards ; Retrospective Studies ; SARS-CoV-2 ; Viral Load |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-05-18 |
| Publishing country | United States |
| Document type | Journal Article |
| ZDB-ID | 2681359-2 |
| ISSN | 2222-1751 ; 2222-1751 |
| ISSN (online) | 2222-1751 |
| ISSN | 2222-1751 |
| DOI | 10.1080/22221751.2020.1771219 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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