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  1. Article ; Online: SARS-CoV-2 can induce brain and spine demyelinating lesions.

    Zanin, Luca / Saraceno, Giorgio / Panciani, Pier Paolo / Renisi, Giulia / Signorini, Liana / Migliorati, Karol / Fontanella, Marco Maria

    Acta neurochirurgica

    2020  Volume 162, Issue 7, Page(s) 1491–1494

    Abstract: ... allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV ... SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache ... for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment ...

    Abstract SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache, anosmia, and dysgeusia are common symptoms. Disturbance of consciousness and seizures can occur as complications in case of severe COVID-19. We described the case of a COVID-19 patient admitted for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV-2. The virus may lead to a SIRS-like immune disorder or play a role of infective trigger. Prompt invasive treatment should be adopted to avoid hypoxic neurotoxicity and prevent CNS injuries.
    Keywords covid19
    Language English
    Publishing date 2020-05-04
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-020-04374-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: SARS-CoV-2 can induce brain and spine demyelinating lesions

    Zanin, Luca / Saraceno, Giorgio / Panciani, Pier Paolo / Renisi, Giulia / Signorini, Liana / Migliorati, Karol / Fontanella, Marco Maria

    Acta Neurochirurgica

    2020  Volume 162, Issue 7, Page(s) 1491–1494

    Keywords Surgery ; Clinical Neurology ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-020-04374-x
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: SARS-CoV-2 can induce brain and spine demyelinating lesions

    Zanin, L. / Saraceno, G. / Panciani, P. P. / Renisi, G. / Signorini, L. / Migliorati, K. / Fontanella, M. M.

    2020  

    Abstract: ... allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV ... SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache ... for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment ...

    Abstract SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache, anosmia, and dysgeusia are common symptoms. Disturbance of consciousness and seizures can occur as complications in case of severe COVID-19. We described the case of a COVID-19 patient admitted for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV-2. The virus may lead to a SIRS-like immune disorder or play a role of infective trigger. Prompt invasive treatment should be adopted to avoid hypoxic neurotoxicity and prevent CNS injuries.
    Keywords COVID-19 ; Demyelinating lesions ; Immune response ; Neuro-COVID ; SARS-CoV-2 ; Seizures ; covid19
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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  4. Article: SARS-CoV-2 can induce brain and spine demyelinating lesions

    Zanin, Luca / Saraceno, Giorgio / Panciani, Pier Paolo / Renisi, Giulia / Signorini, Liana / Migliorati, Karol / Fontanella, Marco Maria

    Acta Neurochir (Wien)

    Abstract: ... allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV ... SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache ... for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment ...

    Abstract SARS-CoV-2 can attack the central nervous system in the early stages of infection. Headache, anosmia, and dysgeusia are common symptoms. Disturbance of consciousness and seizures can occur as complications in case of severe COVID-19. We described the case of a COVID-19 patient admitted for interstitial pneumonia and seizures. MRI showed newly diagnosed demyelinating lesions. High-dose steroid treatment allowed neurological and respiratory recovery. We speculated a delayed immune response induced by SARS-CoV-2. The virus may lead to a SIRS-like immune disorder or play a role of infective trigger. Prompt invasive treatment should be adopted to avoid hypoxic neurotoxicity and prevent CNS injuries.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #165424
    Database COVID19

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  5. Article ; Online: Comment about the article "SARS-CoV-2 can induce brain and spine demyelinating lesions," Acta Neurochir (Wien) 2020 Jul;162(7):1491-1494.

    Fontanella, Marco Maria / Zanin, Luca / Saraceno, Giorgio / Panciani, Pier Paolo / Migliorati, Karol / Latronico, Nicola / Gasparotti, Roberto

    Acta neurochirurgica

    2020  Volume 163, Issue 2, Page(s) 331–332

    Keywords covid19
    Language English
    Publishing date 2020-10-12
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-020-04604-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.180: Show issues Location:
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  6. Article: Comment about the article "SARS-CoV-2 can induce brain and spine demyelinating lesions," Acta Neurochir (Wien) 2020 Jul;162(7):1491-1494

    Fontanella, Marco Maria / Zanin, Luca / Saraceno, Giorgio / Panciani, Pier Paolo / Migliorati, Karol / Latronico, Nicola / Gasparotti, Roberto

    Acta neurochir

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #843907
    Database COVID19

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Acute disseminated encephalomyelitis in a patient vaccinated against SARS-CoV-2.

    Kania, Karolina / Ambrosius, Wojciech / Tokarz Kupczyk, Elzbieta / Kozubski, Wojciech

    Annals of clinical and translational neurology

    2021  Volume 8, Issue 10, Page(s) 2000–2003

    Abstract: ... the first dose of SARS-CoV-2 mRNA vaccine. Brain and spinal cord magnetic resonance imaging (MRI) showed ... Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease, and there are ... distinctive for ADEM widespread demyelinating lesions. The patient was successfully treated ...

    Abstract Acute disseminated encephalomyelitis (ADEM) is a demyelinating disease, and there are some data that link this event with various vaccinations. We report a young female admitted to the hospital with headache, fever, back pain, nausea, vomiting, and urinary retention. Two weeks prior, she received the first dose of SARS-CoV-2 mRNA vaccine. Brain and spinal cord magnetic resonance imaging (MRI) showed distinctive for ADEM widespread demyelinating lesions. The patient was successfully treated with methylprednisolone.
    MeSH term(s) Brain/diagnostic imaging ; COVID-19/prevention & control ; COVID-19 Vaccines/adverse effects ; Encephalomyelitis, Acute Disseminated/chemically induced ; Encephalomyelitis, Acute Disseminated/diagnostic imaging ; Female ; Humans ; Young Adult
    Chemical Substances COVID-19 Vaccines ; mRNA-1273 vaccine (EPK39PL4R4)
    Language English
    Publishing date 2021-09-04
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2740696-9
    ISSN 2328-9503 ; 2328-9503
    ISSN (online) 2328-9503
    ISSN 2328-9503
    DOI 10.1002/acn3.51447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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