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  1. Article: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19.

    Zaorsky, Nicholas G / Yu, James B / McBride, Sean M / Dess, Robert T / Jackson, William C / Mahal, Brandon A / Chen, Ronald / Choudhury, Ananya / Henry, Ann / Syndikus, Isabel / Mitin, Timur / Tree, Alison / Kishan, Amar U / Spratt, Daniel E

    Advances in radiation oncology

    2020  Volume 5, Issue 4, Page(s) 659–665

    Abstract: ... by which to evaluate prostate radiation therapy management decisions.: Methods and materials: Radiation ... to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created ... remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine ...

    Abstract Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic. Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiation therapy management decisions.
    Methods and materials: Radiation oncologists from the United States and the United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created: remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine appropriate approaches.
    Results: Recommendations were provided by the National Comprehensive Cancer Network risk group regarding clinical node-positive, postprostatectomy, oligometastatic, and low-volume M1 disease. Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available. Delays in consultations and return visits of between 1 and 6 months were deemed safe based on stage of disease. Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease. Unfavorable intermediate-risk, high-risk, clinical node-positive, recurrence postsurgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4 to 6 months as necessary. Ultrahypofractionation is preferred for localized, oligometastatic, and low-volume M1, and moderate hypofractionation is preferred for postprostatectomy and clinical node positive disease. Salvage is preferred to adjuvant radiation.
    Conclusions: Resources can be reduced for all identified stages of prostate cancer. The RADS (remote visits, and avoidance, deferment, and shortening of radiation therapy) framework can be applied to other disease sites to help with decision making in a global pandemic.
    Keywords covid19
    Language English
    Publishing date 2020-04-01
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.03.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19.

    Zaorsky, Nicholas G / Yu, James B / McBride, Sean M / Dess, Robert T / Jackson, William C / Mahal, Brandon A / Chen, Ronald / Choudhury, Ananya / Henry, Ann / Syndikus, Isabel / Mitin, Timur / Tree, Alison / Kishan, Amar U / Spratt, Daniel E

    Advances in radiation oncology

    2020  Volume 5, Issue Suppl 1, Page(s) 26–32

    Abstract: ... by which to evaluate prostate radiation therapy management decisions.: Methods and materials: Radiation ... to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created ... remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine ...

    Abstract Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic. Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiation therapy management decisions.
    Methods and materials: Radiation oncologists from the United States and the United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created: remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine appropriate approaches.
    Results: Recommendations were provided by the National Comprehensive Cancer Network risk group regarding clinical node-positive, postprostatectomy, oligometastatic, and low-volume M1 disease. Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available. Delays in consultations and return visits of between 1 and 6 months were deemed safe based on stage of disease. Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease. Unfavorable intermediate-risk, high-risk, clinical node-positive, recurrence postsurgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4 to 6 months as necessary. Ultrahypofractionation is preferred for localized, oligometastatic, and low-volume M1, and moderate hypofractionation is preferred for postprostatectomy and clinical node positive disease. Salvage is preferred to adjuvant radiation.
    Conclusions: Resources can be reduced for all identified stages of prostate cancer. The RADS (remote visits, and avoidance, deferment, and shortening of radiation therapy) framework can be applied to other disease sites to help with decision making in a global pandemic.
    Keywords covid19
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.10.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

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    Inter-library loan at ZB MED

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  3. Article ; Online: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19

    Zaorsky, Nicholas G. / Yu, James B. / McBride, Sean M. / Dess, Robert T. / Jackson, William C. / Mahal, Brandon A. / Chen, Ronald / Choudhury, Ananya / Henry, Ann / Syndikus, Isabel / Mitin, Timur / Tree, Alison / Kishan, Amar U. / Spratt, Daniel E.

    Advances in Radiation Oncology

    2020  Volume 5, Page(s) 26–32

    Keywords Oncology ; Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.10.003
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    Order via subito

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19

    Zaorsky, Nicholas G. / Yu, James B. / McBride, Sean M. / Dess, Robert T. / Jackson, William C. / Mahal, Brandon A. / Chen, Ronald / Choudhury, Ananya / Henry, Ann / Syndikus, Isabel / Mitin, Timur / Tree, Alison / Kishan, Amar U. / Spratt, Daniel E.

    Advances in Radiation Oncology

    2020  Volume 5, Issue 4, Page(s) 659–665

    Keywords Oncology ; Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.03.010
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  5. Article: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19

    Zaorsky, Nicholas G. / Yu, James B. / McBride, Sean M. / Dess, Robert T. / Jackson, William C. / Mahal, Brandon A. / Chen, Ronald Choudhury Ananya Henry Ann Syndikus Isabel Mitin Timur Tree Alison Kishan Amar U. / Spratt, Daniel E.

    Advances in Radiation Oncology

    Abstract: ... by which to evaluate prostate radiation therapy management decisions Methods and Materials Radiation ... to safely manage patients with prostate cancer during the COVID-19 pandemic A RADS framework was created ... remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine ...

    Abstract Purpose During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiation therapy management decisions Methods and Materials Radiation oncologists from the United States and the United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage patients with prostate cancer during the COVID-19 pandemic A RADS framework was created: remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine appropriate approaches Results Recommendations were provided by the National Comprehensive Cancer Network risk group regarding clinical node-positive, postprostatectomy, oligometastatic, and low-volume M1 disease Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available Delays in consultations and return visits of between 1 and 6 months were deemed safe based on stage of disease Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease Unfavorable intermediate-risk, high-risk, clinical node-positive, recurrence postsurgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4 to 6 months as necessary Ultrahypofractionation is preferred for localized, oligometastatic, and low-volume M1, and moderate hypofractionation is preferred for postprostatectomy and clinical node positive disease Salvage is preferred to adjuvant radiation Conclusions Resources can be reduced for all identified stages of prostate cancer The RADS (remote visits, and avoidance, deferment, and shortening of radiation therapy) framework can be applied to other disease sites to help with decision making in a global pandemic
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #893400
    Database COVID19

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Online: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19

    Nicholas G. Zaorsky, MD / James B. Yu, MD / Sean M. McBride, MD / Robert T. Dess, MD / William C. Jackson, MD / Brandon A. Mahal, MD / Ronald Chen, MD / Ananya Choudhury, MD / Ann Henry, MD / Isabel Syndikus, MD / Timur Mitin, MD / Alison Tree, MD / Amar U. Kishan, MD / Daniel E. Spratt, MD

    Advances in Radiation Oncology, Vol 5, Iss , Pp 26-

    2020  Volume 32

    Abstract: ... by which to evaluate prostate radiation therapy management decisions. Methods and Materials: Radiation ... to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created ... remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine ...

    Abstract Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic. Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiation therapy management decisions. Methods and Materials: Radiation oncologists from the United States and the United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created: remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine appropriate approaches. Results: Recommendations were provided by the National Comprehensive Cancer Network risk group regarding clinical node-positive, postprostatectomy, oligometastatic, and low-volume M1 disease. Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available. Delays in consultations and return visits of between 1 and 6 months were deemed safe based on stage of disease. Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease. Unfavorable intermediate-risk, high-risk, clinical node-positive, recurrence postsurgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4 to 6 months as necessary. Ultrahypofractionation is preferred for localized, oligometastatic, and low-volume M1, and moderate hypofractionation is preferred for postprostatectomy and clinical node positive disease. Salvage is preferred to adjuvant radiation. Conclusions: Resources can be reduced for all identified stages of prostate cancer. The RADS (remote visits, and avoidance, deferment, and shortening of radiation therapy) framework can be applied to other disease sites to help with decision making in a global pandemic.
    Keywords Medical physics. Medical radiology. Nuclear medicine ; R895-920 ; Neoplasms. Tumors. Oncology. Including cancer and carcinogens ; RC254-282
    Subject code 610
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

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    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19

    Zaorsky, NG / Yu, JB / McBride, SM / Dess, RT / Jackson, WC / Mahal, BA / Chen, R / Choudhury, A / Henry, A / Syndikus, I / Mitin, T / Tree, A / Kishan, AU / Spratt, DE

    2020  

    Abstract: ... by which to evaluate prostate radiation therapy management decisions. Methods and Materials: Radiation ... to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created ... remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine ...

    Abstract Purpose: During a global pandemic, the benefit of routine visits and treatment of patients with cancer must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers radiation oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic. Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiation therapy management decisions. Methods and Materials: Radiation oncologists from the United States and the United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage patients with prostate cancer during the COVID-19 pandemic. A RADS framework was created: remote visits, and avoidance, deferment, and shortening of radiation therapy was applied to determine appropriate approaches. Results: Recommendations were provided by the National Comprehensive Cancer Network risk group regarding clinical node-positive, postprostatectomy, oligometastatic, and low-volume M1 disease. Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available. Delays in consultations and return visits of between 1 and 6 months were deemed safe based on stage of disease. Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease. Unfavorable intermediate-risk, high-risk, clinical node-positive, recurrence postsurgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4 to 6 months as necessary. Ultrahypofractionation is preferred for localized, oligometastatic, and low-volume M1, and moderate hypofractionation is preferred for postprostatectomy and clinical node positive disease. Salvage is preferred to adjuvant radiation. Conclusions: Resources can be reduced for all identified stages of prostate cancer. The RADS (remote visits, and avoidance, deferment, and shortening of radiation therapy) framework can be applied to other disease sites to help with decision making in a global pandemic.
    Keywords covid19
    Subject code 610
    Publishing date 2020-04-01
    Publisher Elsevier
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

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    Inter-library loan at ZB MED

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  8. Article: Prostate Cancer Radiotherapy Recommendations in Response to COVID-19

    Zaorsky, Nicholas G / Yu, James B / McBride, Sean M / Dess, Robert T / Jackson, William C / Mahal, Brandon A / Chen, Ronald / Choudhury, Ananya / Henry, Ann / Syndikus, Isabel / Mitin, Timur / Tree, Alison / Kishan, Amar U / Spratt, Daniel E

    Abstract: ... manage prostate cancer patients during the COVID-19 pandemic. A RADS framework was created: Remote visits ... to adjuvant radiation. Conclusion: Resources can be reduced for all identified stages of prostate cancer ... prostate radiotherapy management decisions. Patients and Methods: Radiation ...

    Abstract Purpose: During a global pandemic the benefit of routine visits and treatment of cancer patients must be weighed against the risks to patients, staff, and society. Prostate cancer is one of the most common cancers Radiation Oncology departments treat, and efficient resource utilization is essential in the setting of a pandemic. Herein, we aim to establish recommendations and a framework by which to evaluate prostate radiotherapy management decisions. Patients and Methods: Radiation Oncologists from the United States and United Kingdom rapidly conducted a systematic review and agreed upon recommendations to safely manage prostate cancer patients during the COVID-19 pandemic. A RADS framework was created: Remote visits, and Avoidance, Deferment, and Shortening of radiotherapy was applied to determine appropriate approaches. Results: Recommendations are provided by National Comprehensive Cancer Network (NCCN) risk group, including clinical node positive, post-prostatectomy, oligometastatic, and low volume M1 disease. Across all prostate cancer stages, telemedicine consultations and return visits were recommended when resources/staff available. Delays in consultations and return visits was deemed safe based on stage of disease between 1-6 months. Treatment can be avoided or delayed until safe for very low, low, and favorable intermediate-risk disease. Unfavorable intermediate-risk, high-risk, clinical node positive, recurrence post-surgery, oligometastatic, and low-volume M1 disease can receive neoadjuvant hormone therapy for 4-6 months as necessary. Ultrahypofractionation was preferred for localized, oligometastatic, and low volume M1, and moderate hypofractionation was preferred for post-prostatectomy and clinical node positive disease. Salvage was preferred to adjuvant radiation. Conclusion: Resources can be reduced for all identified stages of prostate cancer. The RADS (Remote visits, and Avoidance, Deferment, and Shortening of radiotherapy) framework can be applied to other disease sites to help with decision making in a global pandemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #108732
    Database COVID19

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    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: Management of prostate cancer radiotherapy during the COVID-19 pandemic: A necessary paradigm change.

    Detti, Beatrice / Ingrosso, Gianluca / Becherini, Carlotta / Lancia, Andrea / Olmetto, Emanuela / Alì, Emanuele / Marani, Simona / Teriaca, Maria Ausilia / Francolini, Giulio / Sardaro, Angela / Aristei, Cynthia / Filippi, Andrea Riccardo / Sanguineti, Giuseppe / Livi, Lorenzo

    Cancer treatment and research communications

    2021  Volume 27, Page(s) 100331

    Abstract: Purpose: To adapt the management of prostate malignancy in response to the COVID-19 pandemic ... In Covid-19 Era, the challenge should concern a correct management of the oncologic patient, reducing ... neoadjuvant androgen deprivation therapy (ADT) combined with ultra-hypo-fractionation radiotherapy should be ...

    Abstract Purpose: To adapt the management of prostate malignancy in response to the COVID-19 pandemic.
    Methods: In according to the recommendations of the European Association of Urology, we have developed practical additional document on the treatment of prostate cancer.
    Results: Low-Risk Group Watchful Waiting should be offered to patients >75 years old, with a limited life expectancy and unfit for local treatment. In Active Surveillance (AS) patients re-biopsy, PSA evaluation and visits should be deferred for up to 6 months, preferring non-invasive multiparametric-MRI. The active treatment should be delayed for 6-12 months. Intermediate-Risk Group AS should be offered in favorable-risk patients. Short-course neoadjuvant androgen deprivation therapy (ADT) combined with ultra-hypo-fractionation radiotherapy should be used in unfavorable-risk patients. High-Risk Group Neoadjuvant ADT combined with moderate hypofractionation should be preferred. Whole-pelvis irradiation should be offered to patients with positive lymph nodes in locally advanced setting. ADT should be initiated if PSA doubling time is < 12 months in radio-recurrent patients, as well as in low priority/low volume of metastatic hormone sensitive prostate cancer. If radiotherapy cannot be delayed, hypo-fractionated regimens should be preferred. In high priority class metastatic disease, treatment with androgen receptor-targeted agents should be offered. When palliative radiotherapy for painful bone metastasis is required, single fraction of 8 Gy should be offered.
    Conclusions: In Covid-19 Era, the challenge should concern a correct management of the oncologic patient, reducing the risk of spreading the virus without worsening tumor prognosis.
    MeSH term(s) Aged ; Androgen Antagonists/therapeutic use ; COVID-19/epidemiology ; COVID-19/prevention & control ; COVID-19/virology ; Chemoradiotherapy ; Disease-Free Survival ; Humans ; Male ; Neoadjuvant Therapy ; Pandemics ; Prostate-Specific Antigen/analysis ; Prostatectomy/methods ; Prostatic Neoplasms/diagnosis ; Prostatic Neoplasms/therapy ; Radiation Dose Hypofractionation ; Risk Factors ; SARS-CoV-2/isolation & purification ; SARS-CoV-2/physiology ; Time Factors ; Watchful Waiting/methods
    Chemical Substances Androgen Antagonists ; Prostate-Specific Antigen (EC 3.4.21.77)
    Language English
    Publishing date 2021-02-06
    Publishing country England
    Document type Journal Article ; Review
    ISSN 2468-2942
    ISSN (online) 2468-2942
    DOI 10.1016/j.ctarc.2021.100331
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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