Article ; Online: Clinical characteristics of coronavirus disease (COVID-19) patients with gastrointestinal symptoms: A report of 164 cases.
2020 Volume 52, Issue 10, Page(s) 1076–1079
Abstract: ... with gastrointestinal symptoms.: Methods: The clinical data of 164 COVID-19 patients with gastrointestinal symptoms ... Objective: To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients ... who experience gastrointestinal symptoms is relatively high. Patients who experience gastrointestinal symptoms ...
| Abstract | Objective: To explore the clinical characteristics of Coronavirus Disease (COVID-19) patients with gastrointestinal symptoms. Methods: The clinical data of 164 COVID-19 patients with gastrointestinal symptoms were extracted and analysed retrospectively. Results: In total, 505 COVID-19 patients were divided into two groups: those with gastrointestinal symptoms (G group) and those without gastrointestinal symptoms (NG group). Common gastrointestinal symptoms included inappetence, diarrhoea, nausea, abdominal pain, and vomiting. Significantly higher proportions of patients with fever, dizziness, myalgia, and fatigue were noted in group G than in group NG. Compared with patients without fever, there was a significant difference between G group and NG group in moderate fever or above, while there was no significant difference between the two groups in low fever. The laboratory results showed that patients in the G group had significantly higher C-reactive protein, lactate dehydrogenase, and α-hydroxybutyrate dehydrogenase levels than those in the NG group. Moreover, the proportion of patients with severe pneumonia was significantly higher in the G group than in the NG group. Conclusion: In Wuhan, the proportion of COVID-19 patients who experience gastrointestinal symptoms is relatively high. Patients who experience gastrointestinal symptoms are more likely to suffer from severe pneumonia, which may help clinicians identify patients at high risk of COVID-19 and thus reduce the incidence of this condition. |
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| MeSH term(s) | Abdominal Pain/etiology ; Abdominal Pain/metabolism ; Abdominal Pain/physiopathology ; Adult ; Aged ; Anorexia/etiology ; Anorexia/metabolism ; Anorexia/physiopathology ; Betacoronavirus ; C-Reactive Protein/metabolism ; COVID-19 ; Case-Control Studies ; Coronavirus Infections/complications ; Coronavirus Infections/metabolism ; Coronavirus Infections/physiopathology ; Diarrhea/etiology ; Diarrhea/metabolism ; Diarrhea/physiopathology ; Dizziness/etiology ; Dizziness/physiopathology ; Fatigue/etiology ; Fatigue/physiopathology ; Female ; Fever/etiology ; Fever/physiopathology ; Humans ; Hydroxybutyrate Dehydrogenase/metabolism ; L-Lactate Dehydrogenase/metabolism ; Male ; Middle Aged ; Myalgia/etiology ; Myalgia/physiopathology ; Nausea/etiology ; Nausea/metabolism ; Nausea/physiopathology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/metabolism ; Pneumonia, Viral/physiopathology ; Retrospective Studies ; SARS-CoV-2 ; Severity of Illness Index ; Vomiting/etiology ; Vomiting/metabolism ; Vomiting/physiopathology |
| Chemical Substances | C-Reactive Protein (9007-41-4) ; 2-hydroxybutyrate dehydrogenase (EC 1.1.1.-) ; L-Lactate Dehydrogenase (EC 1.1.1.27) ; Hydroxybutyrate Dehydrogenase (EC 1.1.1.30) |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-05-08 |
| Publishing country | Netherlands |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 1459373-7 |
| ISSN | 1878-3562 ; 1125-8055 |
| ISSN (online) | 1878-3562 |
| ISSN | 1125-8055 |
| DOI | 10.1016/j.dld.2020.04.034 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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