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  1. Article ; Online: Association between regional selenium status and reported outcome of COVID-19 cases in China.

    Zhang, Jinsong / Taylor, Ethan Will / Bennett, Kate / Saad, Ramy / Rayman, Margaret P

    The American journal of clinical nutrition

    2020  Volume 111, Issue 6, Page(s) 1297–1299

    MeSH term(s) Betacoronavirus ; COVID-19 ; Cardiomyopathies/virology ; China/epidemiology ; Coronavirus Infections/epidemiology ; Enterovirus Infections/virology ; Humans ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Selenium/deficiency
    Chemical Substances Selenium (H6241UJ22B)
    Keywords covid19
    Language English
    Publishing date 2020-04-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1093/ajcn/nqaa095
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Association between regional selenium status and reported outcome of COVID-19 cases in China

    Zhang, Jinsong / Taylor, Ethan Will / Bennett, Kate / Saad, Ramy / Rayman, Margaret P

    The American Journal of Clinical Nutrition

    2020  Volume 111, Issue 6, Page(s) 1297–1299

    Keywords Nutrition and Dietetics ; Medicine (miscellaneous) ; covid19
    Language English
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    ZDB-ID 280048-2
    ISSN 1938-3207 ; 0002-9165
    ISSN (online) 1938-3207
    ISSN 0002-9165
    DOI 10.1093/ajcn/nqaa095
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Ue I Zs.208: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Association between regional selenium status and reported outcome of COVID-19 cases in China

    Zhang, Jinsong / Taylor, Ethan Will / Bennett, Kate / Saad, Ramy / Rayman, Margaret P

    Am J Clin Nutr

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #133662
    Database COVID19

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  4. Article ; Online: Association between regional selenium status and reported outcome of COVID-19 cases in China

    Rayman, Margaret / Saad, Ramy / Bennett, Kate / Taylor, Ethan Will / Zhang, Jinsong

    2020  

    Abstract: ... of selenium deficiency running from northeast to southwest in the country and, indeed, China has populations ... that have both the lowest and the highest selenium status in the world. A set of interesting studies ... Potentially relevant to the recent appearance of COVID-19 in China is the fact that there is a belt ...

    Abstract Potentially relevant to the recent appearance of COVID-19 in China is the fact that there is a belt of selenium deficiency running from northeast to southwest in the country and, indeed, China has populations that have both the lowest and the highest selenium status in the world. A set of interesting studies published by the Beck laboratory in the 1990s showed that host selenium deficiency increased the virulence of RNA viruses such as coxsackievirus B3 and influenza A. Passage through a selenium-deficient animal that was unable to produce sufficient antioxidant selenoproteins for its own protection resulted in the virus mutating to a virulent form that caused more severe pathology. Those findings shed light on a human selenium-deficiency disease, a cardiomyopathy known as Keshan disease, named after the area in northeast China where it was endemic. The disease showed a seasonal variation, suggesting a viral cofactor that was later identified as coxsackievirus B3. When the population was supplemented with selenium, the incidence of Keshan disease decreased dramatically.
    Keywords covid19
    Subject code 950
    Language English
    Publishing date 2020-04-28
    Publisher Oxford University Press (OUP)
    Publishing country uk
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Association between fatality rate of COVID-19 and selenium deficiency in China.

    Zhang, Hai-Yang / Zhang, An-Ran / Lu, Qing-Bin / Zhang, Xiao-Ai / Zhang, Zhi-Jie / Guan, Xiu-Gang / Che, Tian-Le / Yang, Yang / Li, Hao / Liu, Wei / Fang, Li-Qun

    BMC infectious diseases

    2021  Volume 21, Issue 1, Page(s) 452

    Abstract: ... between the COVID-19 related fatality and the selenium content both from crops and topsoil, in China ... between CFR of COVID-19 and selenium content in topsoil, with the IRR of 2.38 (95% CIs: 1.14-4.98 ... are needed to explore the associations between selenium status and disease outcome at individual-level. ...

    Abstract Background: COVID-19 has impacted populations around the world, with the fatality rate varying dramatically across countries. Selenium, as one of the important micronutrients implicated in viral infections, was suggested to play roles.
    Methods: An ecological study was performed to assess the association between the COVID-19 related fatality and the selenium content both from crops and topsoil, in China.
    Results: Totally, 14,045 COVID-19 cases were reported from 147 cities during 8 December 2019-13 December 2020 were included. Based on selenium content in crops, the case fatality rates (CFRs) gradually increased from 1.17% in non-selenium-deficient areas, to 1.28% in moderate-selenium-deficient areas, and further to 3.16% in severe-selenium-deficient areas (P = 0.002). Based on selenium content in topsoil, the CFRs gradually increased from 0.76% in non-selenium-deficient areas, to 1.70% in moderate-selenium-deficient areas, and further to 1.85% in severe-selenium-deficient areas (P < 0.001). The zero-inflated negative binomial regression model showed a significantly higher fatality risk in cities with severe-selenium-deficient selenium content in crops than non-selenium-deficient cities, with incidence rate ratio (IRR) of 3.88 (95% CIs: 1.21-12.52), which was further confirmed by regression fitting the association between CFR of COVID-19 and selenium content in topsoil, with the IRR of 2.38 (95% CIs: 1.14-4.98) for moderate-selenium-deficient cities and 3.06 (1.49-6.27) for severe-selenium-deficient cities.
    Conclusions: Regional selenium deficiency might be related to an increased CFR of COVID-19. Future studies are needed to explore the associations between selenium status and disease outcome at individual-level.
    MeSH term(s) COVID-19/diagnosis ; COVID-19/mortality ; COVID-19/virology ; China/epidemiology ; Crops, Agricultural/chemistry ; Humans ; Micronutrients/analysis ; SARS-CoV-2/isolation & purification ; Selenium/analysis ; Selenium/deficiency ; Soil/chemistry ; Survival Analysis
    Chemical Substances Micronutrients ; Soil ; Selenium (H6241UJ22B)
    Language English
    Publishing date 2021-05-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041550-3
    ISSN 1471-2334 ; 1471-2334
    ISSN (online) 1471-2334
    ISSN 1471-2334
    DOI 10.1186/s12879-021-06167-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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