Article ; Online: SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.
2020 Volume 11, Issue 1, Page(s) 6013
Abstract: SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally ... We therefore compare the properties of the mutated S protein (S ...
| Abstract | SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally. We therefore compare the properties of the mutated S protein (S |
|---|---|
| MeSH term(s) | Amino Acid Substitution ; Angiotensin-Converting Enzyme 2/metabolism ; COVID-19/epidemiology ; COVID-19/virology ; HEK293 Cells ; Humans ; Mutation ; Pandemics ; SARS-CoV-2/genetics ; SARS-CoV-2/pathogenicity ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/metabolism ; Virion/metabolism ; Virus Assembly/genetics ; Virus Internalization |
| Chemical Substances | Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23) |
| Language | English |
| Publishing date | 2020-11-26 |
| Publishing country | England |
| Document type | Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S. |
| ZDB-ID | 2553671-0 |
| ISSN | 2041-1723 ; 2041-1723 |
| ISSN (online) | 2041-1723 |
| ISSN | 2041-1723 |
| DOI | 10.1038/s41467-020-19808-4 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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