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  1. Article: Impact of intervention methods on COVID-19 transmission in Shenzhen.

    Zhang, Nan / Cheng, Pan / Jia, Wei / Dung, Chung-Hin / Liu, Li / Chen, Wenzhao / Lei, Hao / Kan, Changcheng / Han, Xiaoyan / Su, Boni / Xiao, Shenglan / Qian, Hua / Lin, Borong / Li, Yuguo

    Building and environment

    2020  Volume 180, Page(s) 107106

    Abstract: By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases ... strategies to prevent outbreaks of COVID-19. ... from Hubei Province had been introduced one week earlier. Intervention strategies implemented in Shenzhen ...

    Abstract By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases were reported, leading to more than 36,000 deaths. In this study, we analysed the efficiency of various intervention strategies to prevent infection by the virus, SARS-CoV-2, using an agent-based SEIIR model, in the fully urbanised city of Shenzhen, Guangdong Province, China. Shortening the duration from symptom onset to hospital admission, quarantining recent arrivals from Hubei Province, and letting symptomatic individuals stay at home were found to be the three most important interventions to reduce the risk of infection in Shenzhen. The ideal time window for a mandatory quarantine of arrivals from Hubei Province was between 10 January and January 17, 2020, while the ideal time window for local intervention strategies was between 15 and 22 January. The risk of infection could have been reduced by 50% if all symptomatic individuals had immediately gone to hospital for isolation, and by 35% if a 14-day quarantine for arrivals from Hubei Province had been introduced one week earlier. Intervention strategies implemented in Shenzhen were effective, and the spread of infection would be controlled even if the initial basic reproduction number had doubled. Our results may be useful for other cities when choosing their intervention strategies to prevent outbreaks of COVID-19.
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country England
    Document type Journal Article
    ISSN 0360-1323
    ISSN 0360-1323
    DOI 10.1016/j.buildenv.2020.107106
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  2. Article ; Online: Impact of intervention methods on COVID-19 transmission in Shenzhen

    Zhang, Nan / Cheng, Pan / Jia, Wei / Dung, Chung-Hin / Liu, Li / Chen, Wenzhao / Lei, Hao / Kan, Changcheng / Han, Xiaoyan / Su, Boni / Xiao, Shenglan / Qian, Hua / Lin, Borong / Li, Yuguo

    Building and Environment

    2020  Volume 180, Page(s) 107106

    Keywords Geography, Planning and Development ; Environmental Engineering ; Civil and Structural Engineering ; Building and Construction ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 0360-1323
    DOI 10.1016/j.buildenv.2020.107106
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Impact of intervention methods on COVID-19 transmission in Shenzhen

    Zhang, Nan / Cheng, Pan / Jia, Wei / Dung, Chung-Hin / Liu, Li / Chen, Wenzhao / Lei, Hao / Kan, Changcheng / Han, Xiaoyan / Su, Boni / Xiao, Shenglan / Qian, Hua / Lin, Borong / Li, Yuguo

    Build. Environ.

    Abstract: By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases ... strategies to prevent outbreaks of COVID-19. ... from Hubei Province had been introduced one week earlier. Intervention strategies implemented in Shenzhen ...

    Abstract By March 31, 2020, COVID-19 had spread to more than 200 countries. Over 750,000 confirmed cases were reported, leading to more than 36,000 deaths. In this study, we analysed the efficiency of various intervention strategies to prevent infection by the virus, SARS-CoV-2, using an agent-based SEIIR model, in the fully urbanised city of Shenzhen, Guangdong Province, China. Shortening the duration from symptom onset to hospital admission, quarantining recent arrivals from Hubei Province, and letting symptomatic individuals stay at home were found to be the three most important interventions to reduce the risk of infection in Shenzhen. The ideal time window for a mandatory quarantine of arrivals from Hubei Province was between 10 January and January 17, 2020, while the ideal time window for local intervention strategies was between 15 and 22 January. The risk of infection could have been reduced by 50% if all symptomatic individuals had immediately gone to hospital for isolation, and by 35% if a 14-day quarantine for arrivals from Hubei Province had been introduced one week earlier. Intervention strategies implemented in Shenzhen were effective, and the spread of infection would be controlled even if the initial basic reproduction number had doubled. Our results may be useful for other cities when choosing their intervention strategies to prevent outbreaks of COVID-19.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #625254
    Database COVID19

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  4. Article ; Online: The impact of COVID-19 on subthreshold depressive symptoms: a longitudinal study.

    Liao, Y H / Fan, B F / Zhang, H M / Guo, L / Lee, Y / Wang, W X / Li, W Y / Gong, M Q / Lui, L M W / Li, L J / Lu, C Y / McIntyre, R S

    Epidemiology and psychiatric sciences

    2021  Volume 30, Page(s) e20

    Abstract: ... to mental health. Herein, we assessed the impact of COVID-19 on subthreshold depressive symptoms and identified ... Conclusions: The COVID-19 pandemic exerted a highly significant and negative impact on symptoms of depression ... Aims: The coronavirus disease 2019 (COVID-19) pandemic represents an unprecedented threat ...

    Abstract Aims: The coronavirus disease 2019 (COVID-19) pandemic represents an unprecedented threat to mental health. Herein, we assessed the impact of COVID-19 on subthreshold depressive symptoms and identified potential mitigating factors.
    Methods: Participants were from Depression Cohort in China (ChiCTR registry number 1900022145). Adults (n = 1722) with subthreshold depressive symptoms were enrolled between March and October 2019 in a 6-month, community-based interventional study that aimed to prevent clinical depression using psychoeducation. A total of 1506 participants completed the study in Shenzhen, China: 726 participants, who completed the study between March 2019 and January 2020 (i.e. before COVID-19), comprised the 'wave 1' group; 780 participants, who were enrolled before COVID-19 and completed the 6-month endpoint assessment during COVID-19, comprised 'wave 2'. Symptoms of depression, anxiety and insomnia were assessed at baseline and endpoint (i.e. 6-month follow-up) using the Patient Health Questionnaire-9 (PHQ-9), Generalised Anxiety Disorder-7 (GAD-7) and Insomnia Severity Index (ISI), respectively. Measures of resilience and regular exercise were assessed at baseline. We compared the mental health outcomes between wave 1 and wave 2 groups. We additionally investigated how mental health outcomes changed across disparate stages of the COVID-19 pandemic in China, i.e. peak (7-13 February), post-peak (14-27 February), remission plateau (28 February-present).
    Results: COVID-19 increased the risk for three mental outcomes: (1) depression (odds ratio [OR] = 1.30, 95% confidence interval [CI]: 1.04-1.62); (2) anxiety (OR = 1.47, 95% CI: 1.16-1.88) and (3) insomnia (OR = 1.37, 95% CI: 1.07-1.77). The highest proportion of probable depression and anxiety was observed post-peak, with 52.9% and 41.4%, respectively. Greater baseline resilience scores had a protective effect on the three main outcomes (depression: OR = 0.26, 95% CI: 0.19-0.37; anxiety: OR = 1.22, 95% CI: 0.14-0.33 and insomnia: OR = 0.18, 95% CI: 0.11-0.28). Furthermore, regular physical activity mitigated the risk for depression (OR = 0.79, 95% CI: 0.79-0.99).
    Conclusions: The COVID-19 pandemic exerted a highly significant and negative impact on symptoms of depression, anxiety and insomnia. Mental health outcomes fluctuated as a function of the duration of the pandemic and were alleviated to some extent with the observed decline in community-based transmission. Augmenting resiliency and regular exercise provide an opportunity to mitigate the risk for mental health symptoms during this severe public health crisis.
    MeSH term(s) Adult ; Anxiety/epidemiology ; Anxiety/psychology ; COVID-19/epidemiology ; COVID-19/psychology ; China/epidemiology ; Cross-Sectional Studies ; Depression/epidemiology ; Depression/psychology ; Female ; Humans ; Longitudinal Studies ; Male ; Mental Health/statistics & numerical data ; Pandemics ; SARS-CoV-2 ; Sleep Initiation and Maintenance Disorders/epidemiology ; Sleep Initiation and Maintenance Disorders/psychology
    Language English
    Publishing date 2021-02-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 2607964-1
    ISSN 2045-7979 ; 2045-7960
    ISSN (online) 2045-7979
    ISSN 2045-7960
    DOI 10.1017/S2045796021000044
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  5. Article ; Online: The impact of relaxing interventions on human contact patterns and SARS-CoV-2 transmission in China.

    Zhang, Juanjuan / Litvinova, Maria / Liang, Yuxia / Zheng, Wen / Shi, Huilin / Vespignani, Alessandro / Viboud, Cecile / Ajelli, Marco / Yu, Hongjie

    Science advances

    2021  Volume 7, Issue 19

    Abstract: ... intensity, timing, and impact on transmission. As a result, post-lockdown COVID-19 dynamics are ... than its pre-pandemic level sufficient to control SARS-CoV-2 transmission. We find that the impact of school ... in transmission. ...

    Abstract Nonpharmaceutical interventions to control SARS-CoV-2 spread have been implemented with different intensity, timing, and impact on transmission. As a result, post-lockdown COVID-19 dynamics are heterogeneous and difficult to interpret. We describe a set of contact surveys performed in four Chinese cities (Wuhan, Shanghai, Shenzhen, and Changsha) during the pre-pandemic, lockdown and post-lockdown periods to quantify changes in contact patterns. In the post-lockdown period, the mean number of contacts increased by 5 to 17% as compared to the lockdown period. However, it remains three to seven times lower than its pre-pandemic level sufficient to control SARS-CoV-2 transmission. We find that the impact of school interventions depends nonlinearly on the intensity of other activities. When most community activities are halted, school closure leads to a 77% decrease in the reproduction number; in contrast, when social mixing outside of schools is at pre-pandemic level, school closure leads to a 5% reduction in transmission.
    MeSH term(s) Adolescent ; Adult ; Aged ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/virology ; Child ; Child, Preschool ; China/epidemiology ; Cities/epidemiology ; Contact Tracing/methods ; Contact Tracing/statistics & numerical data ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Pandemics/prevention & control ; Quarantine ; SARS-CoV-2 ; Surveys and Questionnaires ; Young Adult
    Language English
    Publishing date 2021-05-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2810933-8
    ISSN 2375-2548 ; 2375-2548
    ISSN (online) 2375-2548
    ISSN 2375-2548
    DOI 10.1126/sciadv.abe2584
    Database MEDical Literature Analysis and Retrieval System OnLINE

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