Article: Progress and applications of mass cytometry in sketching immune landscapes.
Clinical and translational medicine
2020 Volume 10, Issue 6, Page(s) e206
Abstract: ... in sketching immune landscape in a wide variety of diseases. ... Recently emerged mass cytometry (cytometry by time-of-flight [CyTOF]) technology permits ... the data yield via CyTOF, and depict the emerging clinical and research applications of CyTOF technology ...
| Abstract | Recently emerged mass cytometry (cytometry by time-of-flight [CyTOF]) technology permits the identification and quantification of inherently diverse cellular systems, and the simultaneous measurement of functional attributes at the single-cell resolution. By virtue of its multiplex ability with limited need for compensation, CyTOF has led a critical role in immunological research fields. Here, we present an overview of CyTOF, including the introduction of CyTOF principle and advantages that make it a standalone tool in deciphering immune mysteries. We then discuss the functional assays, introduce the bioinformatics to interpret the data yield via CyTOF, and depict the emerging clinical and research applications of CyTOF technology in sketching immune landscape in a wide variety of diseases. |
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| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-11-02 |
| Publishing country | United States |
| Document type | Journal Article ; Review |
| ZDB-ID | 2697013-2 |
| ISSN | 2001-1326 |
| ISSN | 2001-1326 |
| DOI | 10.1002/ctm2.206 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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