Article: [Clinical and laboratory characteristics of 215 cases of coronavirus disease 2019 with different prognosis].
Zhonghua wei zhong bing ji jiu yi xue
2021 Volume 32, Issue 12, Page(s) 1428–1433
Abstract: Objective: To analyze the clinical and laboratory characteristics of coronavirus disease 2019 ... of COVID-19.: Methods: The clinical and laboratory characteristics of 215 cases of confirmed COVID-19 ... chest CT scan, and 2019 novel coronavirus (2019-nCoV) nucleic acid tests. The differences of above ...
| Abstract | Objective: To analyze the clinical and laboratory characteristics of coronavirus disease 2019 (COVID-19) patients with different prognosis, and to provide evidence for the diagnosis and treatment of COVID-19. Methods: The clinical and laboratory characteristics of 215 cases of confirmed COVID-19 patients admitted in the First People's Hospital of Tianmen City from January 18 to March 10, 2020 were retrospectively analyzed, including blood cell indexes, inflammatory indexes [C-reactive protein (CRP) and procalcitonin (PCT)], liver function, cardiac function, renal function, blood coagulation function, electrolyte, chest CT scan, and 2019 novel coronavirus (2019-nCoV) nucleic acid tests. The differences of above indexes in the two groups were compared and analyzed. In addition, 55 patients with other viral pneumonia were selected as the control group who admitted to the hospital from August 1 to November 30, 2019. The changes of laboratory indexes of COVID-19 group and control group were observed. Results: In the 215 patients, 206 patients survived and 9 patients died. The average age of survival group was significantly lower than that in the death group, and the average length of hospital stay was significantly longer than the death group. (1) Clinical features: the proportion of underlying diseases in the death group was significantly higher than that in the survival group, such as dyspnea, sore throat, shiver, hypertension, diabetes, coronary heart disease, renal disease, and surgical history. There were no significant differences in other symptoms, signs and underlying diseases between the two group. (2) Laboratory test indexes of the two groups: in death group, white blood cell count [WBC (×10 Conclusions: The major early symptoms of COVID-19 are fever, cough, chest tightness and fatigue. Age and underlying disease may be the risk factors which affect the prognosis of patients with COVID-19. The laboratory indexes such as WBC, NEU, LYM, CRP, PCT, LDH and Cr between death group and survival group were significantly abnormal in the early stages of COVID-19, which would have important implications for the prognosis of patients with COVID-19. Meanwhile, laboratory test indexes, including WBC, NEU, LYM, PLT, RDW-CV, RDW-SD, CRP, Cl |
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| MeSH term(s) | COVID-19 ; Humans ; Laboratories ; Prognosis ; ROC Curve ; Retrospective Studies ; SARS-CoV-2 |
| Language | Chinese |
| Publishing date | 2021-02-05 |
| Publishing country | China |
| Document type | Journal Article |
| ISSN | 2095-4352 |
| ISSN | 2095-4352 |
| DOI | 10.3760/cma.j.cn121430-20200824-00590 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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